Patent number: 6350757
Abstract: A compound selected from those of formula (I):
wherein:
represents single or double bond,
R1 represents hydrogen, alkyl, —R6-aryl, —R6-cycloalkyl, —R6-heterocycle, —CO2R7—, —COR8, or —CONHR8, wherein R6, R7, and R8 are as defined in the description,
R2 represents cyano, mono- or di-alkylaminoalkylaminocarbonyl, —CO2R8, —CONHR8, —NR8R9, —NHCO2R7, or —COR8 wherein R7, R8, and R9 are as defined in the description,
R3 and R4 together form (C3-C10)cycloalkyl,
R5 represents hydrogen, alkyl, or arylalkyl,
Ra, Rb, Rc, Rd, which may be identical or different, represent a group as defined in the description,
its isomers, and pharmaceutically-acceptable acid or base addition salts thereof, and medicinal products containing the same which are useful in the treatment of CNS disorders.
Type:
Grant
Filed:
July 21, 2000
Date of Patent:
February 26, 2002
Assignee:
Les Laboratoires Servier
Inventors:
Solo Goldstein, Guillaume Poissonnet, Jean-Gilles Parmentier, Jean-Daniel Brion, Mark Millan, Anne Dekeyne, Jean Boutin