Abstract: The invention relates to a copolymer containing rigid polyamide PA blocks and flexible blocks, characterized in that it includes at least one carboxylic acid chain end blocked with a polycarbodiimide, said copolymer according to the invention being in noncrosslinked linear form. The invention also relates to the use of a polycarbodiimide in a process for manufacturing a copolymer containing rigid polyamide PA blocks and flexible blocks, including at least one carboxylic acid chain end, for improving the extrudability of the copolymer, the drawability of the copolymer, the abrasion resistance, the tear strength and the durability of the copolymer, without increasing its dispersity.

Abstract: A method of expanding a complex community of microorganisms is provided, an expanded complex community of microorganisms obtained by the method is provided, a pharmaceutical formulation comprising the expanded complex community of microorganisms is provided, and the use of the expanded complex community of microorganisms and the pharmaceutical formulation is provided.

Abstract: Methods, systems, and computer program products for direct assignment of physical devices to confidential virtual machines (VMs). At a first guest privilege context of a guest partition, a direct assignment of a physical device associated with a host computer system to the guest partition is identified. The guest partition includes the first guest privilege context and a second guest privilege context, which is restricted from accessing memory associated with the first guest privilege context. The guest partition corresponds to a confidential VM, such that a memory region associated with the guest partition is inaccessible to a host operating system. It is determined, based on a policy, that the physical device is allowed to be directly assigned to the guest partition. Communication between the physical device and the second guest privilege context is permitted, such as by exposing the physical device on a virtual bus and/or forwarding an interrupt.

Abstract: A spectroscopy device including: an electron source arranged to emit a flux of electrons towards a sample, a pulsed photon source emitting photon pulses towards the sample, at least one spectrometer for receiving a flux of electrons originating from the sample, at least one electron detector; and at least one deflector, between the electron source and the at least one electron detector, synchronized with the pulsed photon source to allow or prevent the passage of electrons emitted by the electron source, towards the electron detector.

Abstract: The disclosed technology is generally directed to code transparency. In one example of the technology, evidence associated with a policy is obtained. The evidence includes data that includes cryptographically verifiable evidence associated with initial source code in accordance with the policy. The initial source code is source code for a CTS. The initial binary is based on the initial source code is executed in a TEE such that a CTS instance begins operation. The CTS instance is configured to register guarantee(s) associated with code approved by the CTS instance. The TEE is used to provide a ledger. The evidence is stored on the ledger. Measurement(s) associated with the binary are provided. A service key associated with CTS instance is generated. TEE attestation of the measurement(s), the evidence, and the service key is provided.

Abstract: The disclosed technology is generally directed to code transparency. In one example of the technology, a claim associated with an application is received. The claim is a document that is signed with a claim signature and that includes evidence associated with a policy, and further includes an expected set of at least one binary measurement associated with the application. The evidence is cryptographically verifiable evidence associated with the application. A trusted execution environment (TEE) is used to provide a distributed ledger. The claim is verified. Verifying the claim includes verifying the expected set of at least one binary measurement associated with the application, verifying the claim signature, and, based at least on the evidence, verifying that the application meets the policy. Upon successful verification of the claim, the claim is appended to the distributed ledger. A ledger countersignature associated with the claim is generated.

Abstract: Compounds of Formula (I): pharmaceutically acceptable salts thereof, deuterated derivatives of any of the foregoing, and metabolites of any of the foregoing are disclosed. Pharmaceutical compositions comprising the same, methods of treating cystic fibrosis using the same, and methods for making the same are also disclosed. Also disclosed are solid state forms of Compound 1 and salts and solvates thereof.

Abstract: Disclosed are systems, methods, and non-transitory computer-readable storage media for shared folder backed integrated workspaces. In some implementations, a content management system can provide a graphical user interface (GUI) that integrates communications and content management into a single user interface. The user interface can include mechanisms that allow a user to provide input to generate a new workspace. The user interface can provide a mechanism to allow a user to view conversations related to the workspace and/or content items associated with the workspace. The user interface can present representations of content items associated with the workspace and allow the user to provide input to generate, view, edit, and share content items associated with the workspace.

Abstract: This disclosure provides modulators of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR), pharmaceutical compositions containing at least one such modulator, methods of treatment of cystic fibrosis using such modulators and pharmaceutical compositions, and processes for making such modulators.

Abstract: Disclosed are systems, methods, and non-transitory computer-readable storage media for shared folder backed integrated workspaces. In some implementations, a content management system can provide a graphical user interface (GUI) that integrates communications and content management into a single user interface. The user interface can include mechanisms that allow a user to provide input to generate a new workspace. The user interface can provide a mechanism to allow a user to view conversations related to the workspace and/or content items associated with the workspace. The user interface can present representations of content items associated with the workspace and allow the user to provide input to generate, view, edit, and share content items associated with the workspace.

Abstract: The present invention features a compound of formula I: or a pharmaceutically acceptable salt thereof, where R1, R2, R3, W, X, Y, Z, n, o, p, and q are defined herein, for the treatment of CFTR mediated diseases, such as cystic fibrosis. The present invention also features pharmaceutical compositions, method of treating, and kits thereof.

Abstract: The invention relates to a piezoelectric motor with bending travelling wave, comprising a rotary shaft (4) connected to a rotor (3), a piezoelectric element (2) attached to a vibrating stator (1), and a decoupling web (5) for attaching the vibrating stator to a mounting (7). The mounting (7) is mechanically connected to a base (9) by means of at least one deformable element (10) and at least one piezoelectric actuator (11), so that the support can be deformed angularly relative to the base in order to rotate the shaft when the vibrating stator is no longer electrically powered. The motor is particularly suitable for applications that require micrometre or nanometre accuracies, for example in positioning tools in industrial processes, precise medical robotics or optical applications.

Abstract: This disclosure relates to translucent oral care compositions comprising one or more source(s) of zinc source and/or a stannous source. The translucent oral care composition can comprise one or more zinc and/or stannous ion source(s) in amounts effective to provide at least 28% soluble zinc and/or stannous as a fraction of the total zinc and/or stannous ion concentration in the composition; an abrasive (e.g., silica), wherein the abrasive has a refractive index of approximately 1.45 as measured in a 4% silica, 90% sorbitol/water solution; and an orally acceptable vehicle. Methods of using and of making these compositions is also disclosed herein.

Abstract: Described herein are oral care compositions comprising an effective amount of a stannous ion source and a taurate surfactant (e.g., sodium methyl cocoyl taurate). In one aspect the compositions of the disclosure can be used for the treatment or reduction of erosive tooth demineralization, gingivitis, plaque, and dental caries.

Abstract: An apparatus and method are provided for inhibiting instruction manipulation. The apparatus has execution circuitry for performing data processing operations in response to a sequence of instructions from an instruction set, and decoder circuitry for decoding each instruction in the sequence in order to generate control signals for the execution circuitry. Each instruction comprises a plurality of instruction bits, and the decoder circuitry is arranged to perform a decode operation on each instruction to determine from the value of each instruction bit, and knowledge of the instruction set, the control signals to be issued to the execution circuitry in response to that instruction. An input path to the decoder circuitry comprises a set of wires over which the instruction bits of each instruction are provided.

Abstract: Disclosed are systems, methods, and non-transitory computer-readable storage media for shared folder backed integrated workspaces. In some implementations, a content management system can provide a graphical user interface (GUI) that integrates communications and content management into a single user interface. The user interface can include mechanisms that allow a user to provide input to generate a new workspace. The user interface can provide a mechanism to allow a user to view conversations related to the workspace and/or content items associated with the workspace. The user interface can present representations of content items associated with the workspace and allow the user to provide input to generate, view, edit, and share content items associated with the workspace.

Abstract: The present invention relates to an isolated polypeptide having beta-lactamase activity and nucleic acid sequences encoding the polypeptide. The isolated polypeptide of the invention is a VIM-2 variant with improved properties such as improved protease stability, stability in intestinal medium, improved activity against one or more antibiotics, improved specific activity and/or improved production in a host cell.

Abstract: A method for de-icing or anti-icing an aircraft portion having at least one piezoelectric element fastened on the inner face of the aircraft portion includes, during a design phase of the aircraft portion, placing the piezoelectric element on an area of the aircraft portion to determine frequencies of resonance and increased dynamic coupling, and during the de-icing or anti-icing of the aircraft portion, the same piezoelectric element is excited according to the natural frequencies of the area.

Abstract: Compounds of Formula I: pharmaceutically acceptable salts thereof, deuterated derivatives of any of the foregoing, and metabolites of any of the foregoing are disclosed. Pharmaceutical compositions comprising the same, methods of treating cystic fibrosis using the same, and methods for making the same are also disclosed.

Abstract: Compounds of Formula (I): pharmaceutically acceptable salts thereof, deuterated derivatives of any of the foregoing, and metabolites of any of the foregoing are disclosed. Pharmaceutical compositions comprising the same, methods of treating cystic fibrosis using the same, and methods for making the same are also disclosed. Also disclosed are solid state forms of Compound 1 and salts and solvates thereof.