Abstract: A flat plate dialysis and ultrafiltration cell and system are provided, having a sample chamber, syringe docking port, with a seal capable of providing a fluid-tight seal after being pierced by a needle, a needle stop capable of preventing a needle from entering the sample chamber, and a needle guide formed in a funnel shape in the syringe docking port to guide a needle toward the sample chamber. The sample chamber is also provided with a dialysis or ultrafiltration membrane provided along a portion of the chamber. The sample chamber is fluidly coupled to a distal end of the syringe docking port and a vent hole.

Abstract: A system and method for identifying the presence of specific nucleotide sequences in a target DNA sample is provided. The nucleotide detection system comprises a flat plate detection cell having a sample chamber, a membrane and an optical window providing optical access to the interior of the cell. A target DNA sample is mixed with labeled nucleotides and other chemistries, and undergoes a chemical reaction, such that if the DNA sample has the nucleotide, the resulting mixture will contain labeled nucleotides that have undergone a change in molecular weight. The reacted sample is applied to the sample chamber and the membrane in the flat plate nucleotide detection system is utilized to effect the separation of the smaller molecular weight labels from the sample.