Patents by Inventor Jean Hypolites Koek
Jean Hypolites Koek has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230180803Abstract: The present invention relates to a method for the preparation of a flavouring, comprising the steps of (i) providing a reaction mixture comprising (a) yeast extract comprising at least 0.5 wt.% of glycosylamine and/or derivatives thereof and at least 1.0 wt.% of thiol containing compounds, wherein the weight percentage is by weight of dry matter of the yeast extract, (b) at least 1 wt.% of mineral acid or organic acid, by weight of the reaction mixture, and (c) from 0 to 20 wt.% of water by weight of the reaction mixture; and (iii) incubating the reaction mixture at a temperature in the range of 150 to 220° C., wherein shear is applied to the reaction mixture. The method preferably is natural. The invention also relates to a flavouring obtainable by the method. The flavouring is preferably a natural flavouring.Type: ApplicationFiled: April 23, 2021Publication date: June 15, 2023Applicant: Conopco Inc., d/b/a UNILEVERInventor: Jean Hypolites Koek
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Publication number: 20220256899Abstract: The present invention relates to a method for the preparation of a flavouring, comprising the steps of (i) providing a reaction mixture comprising yeast extract comprising at least 0.5 wt. %, by weight of dry matter of yeast extract, glycosylamine and/or derivatives thereof and at least 1.0 wt. %, by weight of dry yeast extract, thiol containing compounds; at least 2 wt. %, by weight of the reaction mixture, acid; at least 10 wt. %, by weight of the reaction mixture, water; (ii) heating the reaction mixture at a temperature in the range of 90-160° C.; wherein the heated reaction mixture has an acidity such that a 1 wt. % dilution in demineralised water has a pH of in the range of 3.5 and 6 at 20° C. and (ii) optionally drying the product.Type: ApplicationFiled: October 15, 2019Publication date: August 18, 2022Applicant: Conopco Inc., d/b/a UNILEVERInventors: Amir Maximiliaan Batenburg, Jacoba Carolina van Hoek, Jean Hypolites Koek
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Patent number: 10449249Abstract: Objective of the present invention is to provide polysaccharides which modulate immune response, and which can be used as ingredients in edible products or pharmaceutical compositions. The present invention provides such polysaccharides obtained from the species Camellia sinensis, which comprise a rhamnogalacturonan-I core, and wherein the molar ratio of galacturonyl acid residues to rhamnosyl residues in the backbone of the polysaccharide is close to 1:1. The present invention also provides edible products or pharmaceutical compositions containing such polysaccharides, in order to modulate immune response.Type: GrantFiled: August 3, 2018Date of Patent: October 22, 2019Assignee: NUTRILEADS B.V.Inventors: Ruud Albers, Jari Helin, Werner Klaffke, Jean Hypolites Koek, Petronella Anna Kreijveld, Jari Natunen, Erwin Werner Tareilus, Richardus Paulus Anton Oranje
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Publication number: 20180339040Abstract: Objective of the present invention is to provide polysaccharides which modulate immune response, and which can be used as ingredients in edible products or pharmaceutical compositions. The present invention provides such polysaccharides obtained from the species Camellia sinensis, which comprise a rhamnogalacturonan-I core, and wherein the molar ratio of galacturonyl acid residues to rhamnosyl residues in the backbone of the polysaccharide is close to 1:1. The present invention also provides edible products or pharmaceutical compositions containing such polysaccharides, in order to modulate immune response.Type: ApplicationFiled: August 3, 2018Publication date: November 29, 2018Inventors: Ruud ALBERS, Jari HELIN, Werner KLAFFKE, Jean Hypolites KOEK, Petronella Anna KREIJVELD, Jari NATUNEN, Erwin Werner TAREILUS, Richardus Paulus Anton ORANJE
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Patent number: 10098948Abstract: Objective of the present invention is to provide polysaccharides which modulate immune response, and which can be used as ingredients in edible products or pharmaceutical compositions. The present invention provides such polysaccharides obtained from the species Camellia sinensis, which comprise a rhamnogalacturonan-I core, and wherein the molar ratio of galacturonyl acid residues to rhamnosyl residues in the backbone of the polysaccharide is close to 1:1. The present invention also provides edible products or pharmaceutical compositions containing such polysaccharides, in order to modulate immune response.Type: GrantFiled: February 8, 2016Date of Patent: October 16, 2018Assignee: NUTRILEADS B.V.Inventors: Ruud Albers, Jari Helin, Werner Klaffke, Jean Hypolites Koek, Petronella Anna Kreijveld, Jari Natunen, Erwin Werner Tareilus, Richardus Paulus Anton Oranje
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Patent number: 9951148Abstract: The invention relates to a method for production of a preparation from a vegetable material, said preparation being enriched in a polysaccharide with a backbone comprising rhamnogalacturonan-I cores, said method comprising the steps: mixing the vegetable material with a polar alcoholic solvent; and separating a solid residue obtained in step a) from the solvent; and mixing the solid residue obtained in step b) with a buffered aqueous solution having a pH between 7 and 8. Also provided is a preparation containing rhamnogalacturonan-I pectins that can be obtained by this method and the use of such a preparation to modulate immune response.Type: GrantFiled: April 27, 2012Date of Patent: April 24, 2018Assignee: NutriLeads B.V.Inventors: Jari Helin, Jean Hypolites Koek
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Publication number: 20160151485Abstract: Objective of the present invention is to provide polysaccharides which modulate immune response, and which can be used as ingredients in edible products or pharmaceutical compositions. The present invention provides such polysaccharides obtained from the species Camellia sinensis, which comprise a rhamnogalacturonan-I core, and wherein the molar ratio of galacturonyl acid residues to rhamnosyl residues in the backbone of the polysaccharide is close to 1:1. The present invention also provides edible products or pharmaceutical compositions containing such polysaccharides, in order to modulate immune response.Type: ApplicationFiled: February 8, 2016Publication date: June 2, 2016Applicant: NutriLeads B.V.Inventors: Ruud ALBERS, Jari HELIN, Werner KLAFFKE, Jean Hypolites KOEK, Petronella Anna KREIJVELD, Jari NATUNEN, Erwin Werner TAREILUS, Richardus Paulus Anton ORANJE
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Patent number: 9260535Abstract: Objective of the present invention is to provide polysaccharides which modulate immune response, and which can be used as ingredients in edible products or pharmaceutical compositions. The present invention provides such polysaccharides obtained from the species Camellia sinensis, which comprise a rhamnogalacturonan-I core, and wherein the molar ratio of galacturonyl acid residues to rhamnosyl residues in the backbone of the polysaccharide is close to 1:1. The present invention also provides edible products or pharmaceutical compositions containing such polysaccharides, in order to modulate immune response.Type: GrantFiled: November 16, 2010Date of Patent: February 16, 2016Assignee: NutriLeads B.V.Inventors: Ruud Albers, Jari Helin, Werner Klaffke, Jean Hypolites Koek, Petronella Anna Kreijveld, Jari Natunen, Erwin Werner Tareilus, Richardus Paulus Anton Oranje
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Publication number: 20150164760Abstract: Hair colourant formulations fall into three main categories designated permanent, semi-permanent and temporary. Permanent hair colourant formulations are oxidative dye systems and generally contain paraphenylene diamine (PPD) and resorcinol, both of which have been shown to cause sensitisation and mutagenicity. Furthermore, severe oxidising conditions are required which in themselves cause skin irritation and sensitization as well as hair fibre damage. The inventive composition addresses the aforementioned disadvantages by providing a hair colour composition comprising: (a) Gossypetin; and either (b1) A combination of a peroxidase with either a hydrogen peroxide generator or hydrogen peroxide, or (b2) a laccase; wherein the composition has a pH of 4.5 to 7.0, preferably less than or equal to 6.0.Type: ApplicationFiled: June 19, 2013Publication date: June 18, 2015Inventors: Ranjit Kaur Bhogal, John Casey, Shovan Ganguli, Karl John Hunter, Jean Hypolites Koek, Sally Pamela Redfern
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Patent number: 8907082Abstract: The present invention provides improved processes for the synthesis of 1,4-ditosyl-1,4,7-triazacyclonone, comprising deprotecting a compound of formula (C): wherein P is tosylate or arylsulfonate, with an acidic medium to form 1,2-bis(1,4,7-triazacyclonon-1-yl)-ethane; and subsequently adding formaldehyde and formic acid to the acidic medium to form 1,2-bis-(4,7-dimethyl-1,4,7-triazacyclonon-1-yl)-ethane (Me4-DTNE). The syntheses of intermediates are also disclosed.Type: GrantFiled: July 5, 2011Date of Patent: December 9, 2014Assignee: Catexel LimitedInventors: Ronald Hage, Jean Hypolites Koek, Stephen William Russell, Lodewijk Van der Wolf, Jianrong Zhang, Wei Zhao, Xiaohong Wang
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Publication number: 20140213436Abstract: The present invention concerns bleaching of substrates with an aqueous solution of a water soluble salt of a preformed transition metal catalyst together with hydrogen peroxide.Type: ApplicationFiled: March 28, 2014Publication date: July 31, 2014Applicant: CONOPCO INC., D/B/A UNILVERInventors: RONALD HAGE, JEAN HYPOLITES KOEK, MARINUS MARIA CORNELIS GERARDUS WARMOESKERKEN
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Patent number: 8722608Abstract: The present invention concerns bleaching of substrates with an aqueous solution of a water soluble salt of a preformed transition metal catalyst together with hydrogen peroxide.Type: GrantFiled: May 29, 2013Date of Patent: May 13, 2014Assignee: Conopco, Inc.Inventors: Ronald Hage, Jean Hypolites Koek, Marinus Maria Cornelis Gerardus Warmoeskerken
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Publication number: 20140056946Abstract: The invention relates to a method for production of a preparation from a vegetable material, said preparation being enriched in a polysaccharide with a backbone comprising rhamnogalacturonan-I cores, said method comprising the steps: mixing the vegetable material with a polar alcoholic solvent; and separating a solid residue obtained in step a) from the solvent; and mixing the solid residue obtained in step b) with a buffered aqueous solution having a pH between 7 and 8. Also provided is a preparation containing rhamnogalacturonan-I pectins that can be obtained by this method and the use of such a preparation to modulate immune response.Type: ApplicationFiled: April 27, 2012Publication date: February 27, 2014Inventors: Jari Helin, Jean Hypolites Koek
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Publication number: 20130266530Abstract: Hair colourant formulations fall into three main categories designated permanent, semi-permanent and temporary. Permanent hair colourant formulations are oxidative dye systems and generally contain paraphenylene diamine (PPD) and resorcinol, both of which have been shown to cause sensitisation and mutagenicity. Furthermore, severe oxidising conditions are required which in themselves cause skin irritation and sensitization as well as hair fibre damage. The inventive method addresses the aforementioned disadvantages by providing a method of colouring hair fibres, the method comprising the step of applying a hair colour composition, the hair colour composition comprising: (a) (+)-Catechin, (?)-catechin, (+)-epicatechin, (?)-epicatechin or mixtures thereof; (b) A hydrogen peroxide generator or hydrogen peroxide; and (c) A peroxidase and; wherein the composition has a pH of 4.5 to 7.0, preferably less than or equal to 6.0.Type: ApplicationFiled: December 12, 2011Publication date: October 10, 2013Inventors: Ranjit Kaur Bhogal, John Casey, Shovan Ganguli, Karl John Hunter, Jean Hypolites Koek, Sally Pamela Redfern
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Publication number: 20130261297Abstract: The present invention provides improved processes for the synthesis of 1,4-ditosyl-1,4,7-triazacyclonone and protected analogues thereof, and to synthesise bis(triazacyclononane) ligands.Type: ApplicationFiled: July 5, 2011Publication date: October 3, 2013Applicant: CATEXEL LIMITEDInventors: Ronald Hage, Jean Hypolites Koek, Stephen William Russell, Lodewijk Van der Wolf, Jianrong Zhang, Wei Zhao, Xiaohong Wang
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Publication number: 20130260986Abstract: The present invention concerns bleaching of substrates with an aqueous solution of a water soluble salt of a preformed transition metal catalyst together with hydrogen peroxide.Type: ApplicationFiled: May 29, 2013Publication date: October 3, 2013Applicant: CONOPCO INC.Inventors: RONALD HAGE, JEAN HYPOLITES KOEK, MARINUS MARIA CORNELIS GERARDUS WARMOESKERKEN
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Patent number: 8455423Abstract: An aqueous solution of a water soluble salt of a preformed transition metal catalyst together with hydrogen peroxide is disclosed. The composition is useful in bleaching a variety of substrates.Type: GrantFiled: July 6, 2011Date of Patent: June 4, 2013Assignee: Conopco, Inc.Inventors: Ronald Hage, Jean Hypolites Koek, Marinus Maria Cornelis Gerardus Warmoeskerken
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Publication number: 20130064858Abstract: Objective of the present invention is to provide polysaccharides which modulate immune response, and which can be used as ingredients in edible products or pharmaceutical compositions. The present invention provides such polysaccharides obtained from the species Camellia sinensis, which comprise a rhamnogalacturonan-I core, and wherein the molar ratio of galacturonyl acid residues to rhamnosyl residues in the backbone of the polysaccharide is close to 1:1. The present invention also provides edible products or pharmaceutical compositions containing such polysaccharides, in order to modulate immune response.Type: ApplicationFiled: November 16, 2010Publication date: March 14, 2013Inventors: Ruud Albers, Jari Helin, Werner Klaffke, Jean Hypolites Koek, Petronella Anna Kreijveld, Jari Natunen, Erwin Werner Tareilus, Richardus Paulus Anton Oranje
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Publication number: 20110275510Abstract: An aqueous solution of a water soluble salt of a preformed transition metal catalyst together with hydrogen peroxide is disclosed. The composition is useful in bleaching a variety of substrates.Type: ApplicationFiled: July 6, 2011Publication date: November 10, 2011Applicant: Conopco Inc.Inventors: Ronald Hage, Jean Hypolites Koek, Marinus Maria Cornelis Gerardus Warmoeskerken
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Publication number: 20100316660Abstract: There is provided an edible product having an immunostimulating effect, said product comprising polysaccharides obtainable from the Alliaceae family of the perennial flowering plants. Also provided is a process for preparing such an edible product and composition comprising from 0.Type: ApplicationFiled: December 2, 2008Publication date: December 16, 2010Inventors: Johanna Alida Van Adrichem, Wilhelmina Martina Blom, Yvonne Elisabeth Maria Dommels, Jean Hypolites Koek