Patents by Inventor Jean Hypolites Koek

Jean Hypolites Koek has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230180803
    Abstract: The present invention relates to a method for the preparation of a flavouring, comprising the steps of (i) providing a reaction mixture comprising (a) yeast extract comprising at least 0.5 wt.% of glycosylamine and/or derivatives thereof and at least 1.0 wt.% of thiol containing compounds, wherein the weight percentage is by weight of dry matter of the yeast extract, (b) at least 1 wt.% of mineral acid or organic acid, by weight of the reaction mixture, and (c) from 0 to 20 wt.% of water by weight of the reaction mixture; and (iii) incubating the reaction mixture at a temperature in the range of 150 to 220° C., wherein shear is applied to the reaction mixture. The method preferably is natural. The invention also relates to a flavouring obtainable by the method. The flavouring is preferably a natural flavouring.
    Type: Application
    Filed: April 23, 2021
    Publication date: June 15, 2023
    Applicant: Conopco Inc., d/b/a UNILEVER
    Inventor: Jean Hypolites Koek
  • Publication number: 20220256899
    Abstract: The present invention relates to a method for the preparation of a flavouring, comprising the steps of (i) providing a reaction mixture comprising yeast extract comprising at least 0.5 wt. %, by weight of dry matter of yeast extract, glycosylamine and/or derivatives thereof and at least 1.0 wt. %, by weight of dry yeast extract, thiol containing compounds; at least 2 wt. %, by weight of the reaction mixture, acid; at least 10 wt. %, by weight of the reaction mixture, water; (ii) heating the reaction mixture at a temperature in the range of 90-160° C.; wherein the heated reaction mixture has an acidity such that a 1 wt. % dilution in demineralised water has a pH of in the range of 3.5 and 6 at 20° C. and (ii) optionally drying the product.
    Type: Application
    Filed: October 15, 2019
    Publication date: August 18, 2022
    Applicant: Conopco Inc., d/b/a UNILEVER
    Inventors: Amir Maximiliaan Batenburg, Jacoba Carolina van Hoek, Jean Hypolites Koek
  • Patent number: 10449249
    Abstract: Objective of the present invention is to provide polysaccharides which modulate immune response, and which can be used as ingredients in edible products or pharmaceutical compositions. The present invention provides such polysaccharides obtained from the species Camellia sinensis, which comprise a rhamnogalacturonan-I core, and wherein the molar ratio of galacturonyl acid residues to rhamnosyl residues in the backbone of the polysaccharide is close to 1:1. The present invention also provides edible products or pharmaceutical compositions containing such polysaccharides, in order to modulate immune response.
    Type: Grant
    Filed: August 3, 2018
    Date of Patent: October 22, 2019
    Assignee: NUTRILEADS B.V.
    Inventors: Ruud Albers, Jari Helin, Werner Klaffke, Jean Hypolites Koek, Petronella Anna Kreijveld, Jari Natunen, Erwin Werner Tareilus, Richardus Paulus Anton Oranje
  • Publication number: 20180339040
    Abstract: Objective of the present invention is to provide polysaccharides which modulate immune response, and which can be used as ingredients in edible products or pharmaceutical compositions. The present invention provides such polysaccharides obtained from the species Camellia sinensis, which comprise a rhamnogalacturonan-I core, and wherein the molar ratio of galacturonyl acid residues to rhamnosyl residues in the backbone of the polysaccharide is close to 1:1. The present invention also provides edible products or pharmaceutical compositions containing such polysaccharides, in order to modulate immune response.
    Type: Application
    Filed: August 3, 2018
    Publication date: November 29, 2018
    Inventors: Ruud ALBERS, Jari HELIN, Werner KLAFFKE, Jean Hypolites KOEK, Petronella Anna KREIJVELD, Jari NATUNEN, Erwin Werner TAREILUS, Richardus Paulus Anton ORANJE
  • Patent number: 10098948
    Abstract: Objective of the present invention is to provide polysaccharides which modulate immune response, and which can be used as ingredients in edible products or pharmaceutical compositions. The present invention provides such polysaccharides obtained from the species Camellia sinensis, which comprise a rhamnogalacturonan-I core, and wherein the molar ratio of galacturonyl acid residues to rhamnosyl residues in the backbone of the polysaccharide is close to 1:1. The present invention also provides edible products or pharmaceutical compositions containing such polysaccharides, in order to modulate immune response.
    Type: Grant
    Filed: February 8, 2016
    Date of Patent: October 16, 2018
    Assignee: NUTRILEADS B.V.
    Inventors: Ruud Albers, Jari Helin, Werner Klaffke, Jean Hypolites Koek, Petronella Anna Kreijveld, Jari Natunen, Erwin Werner Tareilus, Richardus Paulus Anton Oranje
  • Patent number: 9951148
    Abstract: The invention relates to a method for production of a preparation from a vegetable material, said preparation being enriched in a polysaccharide with a backbone comprising rhamnogalacturonan-I cores, said method comprising the steps: mixing the vegetable material with a polar alcoholic solvent; and separating a solid residue obtained in step a) from the solvent; and mixing the solid residue obtained in step b) with a buffered aqueous solution having a pH between 7 and 8. Also provided is a preparation containing rhamnogalacturonan-I pectins that can be obtained by this method and the use of such a preparation to modulate immune response.
    Type: Grant
    Filed: April 27, 2012
    Date of Patent: April 24, 2018
    Assignee: NutriLeads B.V.
    Inventors: Jari Helin, Jean Hypolites Koek
  • Publication number: 20160151485
    Abstract: Objective of the present invention is to provide polysaccharides which modulate immune response, and which can be used as ingredients in edible products or pharmaceutical compositions. The present invention provides such polysaccharides obtained from the species Camellia sinensis, which comprise a rhamnogalacturonan-I core, and wherein the molar ratio of galacturonyl acid residues to rhamnosyl residues in the backbone of the polysaccharide is close to 1:1. The present invention also provides edible products or pharmaceutical compositions containing such polysaccharides, in order to modulate immune response.
    Type: Application
    Filed: February 8, 2016
    Publication date: June 2, 2016
    Applicant: NutriLeads B.V.
    Inventors: Ruud ALBERS, Jari HELIN, Werner KLAFFKE, Jean Hypolites KOEK, Petronella Anna KREIJVELD, Jari NATUNEN, Erwin Werner TAREILUS, Richardus Paulus Anton ORANJE
  • Patent number: 9260535
    Abstract: Objective of the present invention is to provide polysaccharides which modulate immune response, and which can be used as ingredients in edible products or pharmaceutical compositions. The present invention provides such polysaccharides obtained from the species Camellia sinensis, which comprise a rhamnogalacturonan-I core, and wherein the molar ratio of galacturonyl acid residues to rhamnosyl residues in the backbone of the polysaccharide is close to 1:1. The present invention also provides edible products or pharmaceutical compositions containing such polysaccharides, in order to modulate immune response.
    Type: Grant
    Filed: November 16, 2010
    Date of Patent: February 16, 2016
    Assignee: NutriLeads B.V.
    Inventors: Ruud Albers, Jari Helin, Werner Klaffke, Jean Hypolites Koek, Petronella Anna Kreijveld, Jari Natunen, Erwin Werner Tareilus, Richardus Paulus Anton Oranje
  • Publication number: 20150164760
    Abstract: Hair colourant formulations fall into three main categories designated permanent, semi-permanent and temporary. Permanent hair colourant formulations are oxidative dye systems and generally contain paraphenylene diamine (PPD) and resorcinol, both of which have been shown to cause sensitisation and mutagenicity. Furthermore, severe oxidising conditions are required which in themselves cause skin irritation and sensitization as well as hair fibre damage. The inventive composition addresses the aforementioned disadvantages by providing a hair colour composition comprising: (a) Gossypetin; and either (b1) A combination of a peroxidase with either a hydrogen peroxide generator or hydrogen peroxide, or (b2) a laccase; wherein the composition has a pH of 4.5 to 7.0, preferably less than or equal to 6.0.
    Type: Application
    Filed: June 19, 2013
    Publication date: June 18, 2015
    Inventors: Ranjit Kaur Bhogal, John Casey, Shovan Ganguli, Karl John Hunter, Jean Hypolites Koek, Sally Pamela Redfern
  • Patent number: 8907082
    Abstract: The present invention provides improved processes for the synthesis of 1,4-ditosyl-1,4,7-triazacyclonone, comprising deprotecting a compound of formula (C): wherein P is tosylate or arylsulfonate, with an acidic medium to form 1,2-bis(1,4,7-triazacyclonon-1-yl)-ethane; and subsequently adding formaldehyde and formic acid to the acidic medium to form 1,2-bis-(4,7-dimethyl-1,4,7-triazacyclonon-1-yl)-ethane (Me4-DTNE). The syntheses of intermediates are also disclosed.
    Type: Grant
    Filed: July 5, 2011
    Date of Patent: December 9, 2014
    Assignee: Catexel Limited
    Inventors: Ronald Hage, Jean Hypolites Koek, Stephen William Russell, Lodewijk Van der Wolf, Jianrong Zhang, Wei Zhao, Xiaohong Wang
  • Publication number: 20140213436
    Abstract: The present invention concerns bleaching of substrates with an aqueous solution of a water soluble salt of a preformed transition metal catalyst together with hydrogen peroxide.
    Type: Application
    Filed: March 28, 2014
    Publication date: July 31, 2014
    Applicant: CONOPCO INC., D/B/A UNILVER
    Inventors: RONALD HAGE, JEAN HYPOLITES KOEK, MARINUS MARIA CORNELIS GERARDUS WARMOESKERKEN
  • Patent number: 8722608
    Abstract: The present invention concerns bleaching of substrates with an aqueous solution of a water soluble salt of a preformed transition metal catalyst together with hydrogen peroxide.
    Type: Grant
    Filed: May 29, 2013
    Date of Patent: May 13, 2014
    Assignee: Conopco, Inc.
    Inventors: Ronald Hage, Jean Hypolites Koek, Marinus Maria Cornelis Gerardus Warmoeskerken
  • Publication number: 20140056946
    Abstract: The invention relates to a method for production of a preparation from a vegetable material, said preparation being enriched in a polysaccharide with a backbone comprising rhamnogalacturonan-I cores, said method comprising the steps: mixing the vegetable material with a polar alcoholic solvent; and separating a solid residue obtained in step a) from the solvent; and mixing the solid residue obtained in step b) with a buffered aqueous solution having a pH between 7 and 8. Also provided is a preparation containing rhamnogalacturonan-I pectins that can be obtained by this method and the use of such a preparation to modulate immune response.
    Type: Application
    Filed: April 27, 2012
    Publication date: February 27, 2014
    Inventors: Jari Helin, Jean Hypolites Koek
  • Publication number: 20130266530
    Abstract: Hair colourant formulations fall into three main categories designated permanent, semi-permanent and temporary. Permanent hair colourant formulations are oxidative dye systems and generally contain paraphenylene diamine (PPD) and resorcinol, both of which have been shown to cause sensitisation and mutagenicity. Furthermore, severe oxidising conditions are required which in themselves cause skin irritation and sensitization as well as hair fibre damage. The inventive method addresses the aforementioned disadvantages by providing a method of colouring hair fibres, the method comprising the step of applying a hair colour composition, the hair colour composition comprising: (a) (+)-Catechin, (?)-catechin, (+)-epicatechin, (?)-epicatechin or mixtures thereof; (b) A hydrogen peroxide generator or hydrogen peroxide; and (c) A peroxidase and; wherein the composition has a pH of 4.5 to 7.0, preferably less than or equal to 6.0.
    Type: Application
    Filed: December 12, 2011
    Publication date: October 10, 2013
    Inventors: Ranjit Kaur Bhogal, John Casey, Shovan Ganguli, Karl John Hunter, Jean Hypolites Koek, Sally Pamela Redfern
  • Publication number: 20130261297
    Abstract: The present invention provides improved processes for the synthesis of 1,4-ditosyl-1,4,7-triazacyclonone and protected analogues thereof, and to synthesise bis(triazacyclononane) ligands.
    Type: Application
    Filed: July 5, 2011
    Publication date: October 3, 2013
    Applicant: CATEXEL LIMITED
    Inventors: Ronald Hage, Jean Hypolites Koek, Stephen William Russell, Lodewijk Van der Wolf, Jianrong Zhang, Wei Zhao, Xiaohong Wang
  • Publication number: 20130260986
    Abstract: The present invention concerns bleaching of substrates with an aqueous solution of a water soluble salt of a preformed transition metal catalyst together with hydrogen peroxide.
    Type: Application
    Filed: May 29, 2013
    Publication date: October 3, 2013
    Applicant: CONOPCO INC.
    Inventors: RONALD HAGE, JEAN HYPOLITES KOEK, MARINUS MARIA CORNELIS GERARDUS WARMOESKERKEN
  • Patent number: 8455423
    Abstract: An aqueous solution of a water soluble salt of a preformed transition metal catalyst together with hydrogen peroxide is disclosed. The composition is useful in bleaching a variety of substrates.
    Type: Grant
    Filed: July 6, 2011
    Date of Patent: June 4, 2013
    Assignee: Conopco, Inc.
    Inventors: Ronald Hage, Jean Hypolites Koek, Marinus Maria Cornelis Gerardus Warmoeskerken
  • Publication number: 20130064858
    Abstract: Objective of the present invention is to provide polysaccharides which modulate immune response, and which can be used as ingredients in edible products or pharmaceutical compositions. The present invention provides such polysaccharides obtained from the species Camellia sinensis, which comprise a rhamnogalacturonan-I core, and wherein the molar ratio of galacturonyl acid residues to rhamnosyl residues in the backbone of the polysaccharide is close to 1:1. The present invention also provides edible products or pharmaceutical compositions containing such polysaccharides, in order to modulate immune response.
    Type: Application
    Filed: November 16, 2010
    Publication date: March 14, 2013
    Inventors: Ruud Albers, Jari Helin, Werner Klaffke, Jean Hypolites Koek, Petronella Anna Kreijveld, Jari Natunen, Erwin Werner Tareilus, Richardus Paulus Anton Oranje
  • Publication number: 20110275510
    Abstract: An aqueous solution of a water soluble salt of a preformed transition metal catalyst together with hydrogen peroxide is disclosed. The composition is useful in bleaching a variety of substrates.
    Type: Application
    Filed: July 6, 2011
    Publication date: November 10, 2011
    Applicant: Conopco Inc.
    Inventors: Ronald Hage, Jean Hypolites Koek, Marinus Maria Cornelis Gerardus Warmoeskerken
  • Publication number: 20100316660
    Abstract: There is provided an edible product having an immunostimulating effect, said product comprising polysaccharides obtainable from the Alliaceae family of the perennial flowering plants. Also provided is a process for preparing such an edible product and composition comprising from 0.
    Type: Application
    Filed: December 2, 2008
    Publication date: December 16, 2010
    Inventors: Johanna Alida Van Adrichem, Wilhelmina Martina Blom, Yvonne Elisabeth Maria Dommels, Jean Hypolites Koek