Patents by Inventor Jean Laurent
Jean Laurent has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10736908Abstract: Compounds of Formula (I): (Formula (I)) and their pharmaceutically acceptable salts are useful for the inhibition of HIV reverse transcriptase. The compounds may also be useful for the prophylaxis or treatment of infection by HIV and in the prophylaxis, delay in the onset or progression, and treatment of AIDS. The compounds and their salts can be employed as ingredients in pharmaceutical compositions, optionally in combination with other antiviral agents, immunomodulators, antibiotics or vaccines.Type: GrantFiled: October 20, 2017Date of Patent: August 11, 2020Assignees: MERCK SHARP & DOHME CORP., IDENIX PHARMACEUTICALS LLCInventors: Jean-Laurent Paparin, Houcine Rahali, Aurélien Salanson, Daniel Da Costa, David Dukhan, Timothy J. Hartingh, Izzat Raheem, John Schreier
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Publication number: 20200225382Abstract: A system and method is provided for restoring a 3D tomographic model of the Earth's subsurface geology from the present-day to a past restoration time. Whereas at the present time all faults represent active discontinuities, at a past restoration time some faults have not yet formed. Accordingly, the restored model divides the fault network into ?-active faults (discontinuous surfaces for faults that intersect the layer deposited at the past restoration time) and ?-inactive faults (continuous surfaces for faults that do not intersect the layer deposited at the past restoration time). A new 3D restoration transformation is also provided that uses linear geological constraints to process the restoration model in less time and generate more accurate geological images.Type: ApplicationFiled: November 12, 2019Publication date: July 16, 2020Applicants: Emerson Paradigm Holding LLCInventors: Jean-Laurent MALLET, Anne-Laure TERTOIS
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Publication number: 20200225383Abstract: A system and method is provided for restoring a 3D tomographic model of the Earth's subsurface geology from the present-day to a past restoration time. Whereas at the present time all faults represent active discontinuities, at a past restoration time some faults have not yet formed. Accordingly, the restored model divides the fault network into ?-active faults (discontinuous surfaces for faults that intersect the layer deposited at the past restoration time) and ?-inactive faults (continuous surfaces for faults that do not intersect the layer deposited at the past restoration time). A new 3D restoration transformation is also provided that uses linear geological constraints to process the restoration model in less time and generate more accurate geological images.Type: ApplicationFiled: March 3, 2020Publication date: July 16, 2020Applicants: Emerson Paradigm Holding LLCInventors: Jean-Laurent MALLET, Anne-Laure TERTOIS
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Patent number: 10705254Abstract: A system and method is provided for restoring a 3D tomographic model of the Earth's subsurface geology from the present-day to a past restoration time. Whereas at the present time all faults represent active discontinuities, at a past restoration time some faults have not yet formed. Accordingly, the restored model divides the fault network into ?-active faults (discontinuous surfaces for faults that intersect the layer deposited at the past restoration time) and ?-inactive faults (continuous surfaces for faults that do not intersect the layer deposited at the past restoration time). A new 3D restoration transformation is also provided that uses linear geological constraints to process the restoration model in less time and generate more accurate geological images.Type: GrantFiled: November 12, 2019Date of Patent: July 7, 2020Assignees: Emerson Paradigm Holding LLCInventors: Jean-Laurent Mallet, Anne-Laure Tertois
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Patent number: 10677100Abstract: A support system (16) for a structural casing of a turbomachine (10), which comprises: a handling fitting (17) comprising a front edge (19) provided with one or more hole(s) (26) for receiving one or more screw(s) (24) for attachment to a flange (23) formed on the casing (10), a rear edge (20) provided with a cavity (32) for receiving a projecting boss (29) formed on the casing (10); a pair of jaws (31) for gripping the boss (29), that are mounted in the cavity (32); at least one screw (33) for adjusting the position of the jaws (31), mounted on the fitting (17) and engaging with at least one jaw (31).Type: GrantFiled: May 19, 2017Date of Patent: June 9, 2020Assignee: SAFRAN AIRCRAFT ENGINESInventors: Patrick Sultana, Sébastien Jean Laurent Prestel, Olivier Renon, Benoit Argémiro Matthieu Debray, Guillaume Sevi
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Patent number: 10648366Abstract: The invention relates to an exhaust casing for a turbine engine of an aircraft, including: a collar (4), a hub (5), hollow arms (63) connecting said collar (4) to said hub (5), and an opening piece (3) which is located on the collar (4) and is suitable for being connected to an outlet tube (30) of a transient-operation valve of the turbine engine. In said exhaust casing, said opening piece (3) is attached onto the collar (4) and forms an extension of a hollow arm (63) such that an air flow (7) leaving the outlet tube (30) of the transient-operation valve penetrates the hollow arm (63) and flows into the hub (5).Type: GrantFiled: July 20, 2016Date of Patent: May 12, 2020Assignee: SAFRAN AIRCRAFT ENGINESInventors: Baptiste Marie Aubin Pierre Jouy, Bertrand Guillaume Robin Pellaton, Sebastien Jean Laurent Prestel
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Patent number: 10598819Abstract: A method and system for computing and visualizing sedimentary attributes may include receiving, by a processor, paleo-geographic coordinates representing predicted approximate positions of particles of sediment deposited at a time period when a layer was originally formed. The processor may numerically compute or determine a sedimentation rate that varies laterally along the layer. The processor may determine a sedimentary attribute based on the lateral variation of the sedimentation rate along the layer with respect to the paleo-geographic coordinates. A monitor or display may display the sedimentary attribute of the layer in the present-day geological space.Type: GrantFiled: February 13, 2019Date of Patent: March 24, 2020Assignee: EMERSON PARADIGM HOLDING LLCInventor: Jean-Laurent Mallet
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Patent number: 10520644Abstract: A system and method is provided for restoring a 3D tomographic model of the Earth's subsurface geology from the present-day to a past restoration time. Whereas at the present time all faults represent active discontinuities, at a past restoration time some faults have not yet formed. Accordingly, the restored model divides the fault network into ?-active faults (discontinuous surfaces for faults that intersect the layer deposited at the past restoration time) and ?-inactive faults (continuous surfaces for faults that do not intersect the layer deposited at the past restoration time). A new 3D restoration transformation is also provided that uses linear geological constraints to process the restoration model in less time and generate more accurate geological images.Type: GrantFiled: January 10, 2019Date of Patent: December 31, 2019Assignee: EMERSON PARADIGM HOLDING LLCInventors: Jean-Laurent Mallet, Anne-Laure Tertois
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Patent number: 10519159Abstract: Compounds of Formula I: and their pharmaceutically acceptable salts are useful for the inhibition of HIV reverse transcriptase. The compounds may also be useful for the prophylaxis or treatment of infection by HIV and in the prophylaxis, delay in the onset or progression, and treatment of AIDS. The compounds and their salts can be employed as ingredients in pharmaceutical compositions, optionally in combination with other antiviral agents, immunomodulators, antibiotics or vaccines.Type: GrantFiled: December 20, 2017Date of Patent: December 31, 2019Assignees: Merck Sharp & Dohme Corp., Idenix Pharmaceuticals, LLC.Inventors: Jean-Laurent Paparin, Izzat Raheem, Houcine Rahali, Daniel Da Costa, David Dukhan
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Patent number: 10481245Abstract: The concepts, systems and methods described herein are directed towards frequency jump burst-pulse-Doppler (FJB-PD) waveforms and processing to provide wideband, high range resolution (HRR) radar profiling capability in a clutter dense environment. The method includes transmitting a FJB-PD waveform comprising a plurality of frequency steps over a predetermined time period with each frequency step having a plurality of pulses. The method further includes receiving one or more FJB-PD pulse returns corresponding to the FJB-PD waveform and identifying one or more target detections in the one or more FJB-PD pulse returns. A set of range swaths may be extracted for each of the one or more target detections and a wideband spectrum may be generated for each of the sets of range swaths using FJB coherent integration. A clutter suppressed HRR profile may be generated for each of the target detections based on the respective wideband spectrum.Type: GrantFiled: July 1, 2016Date of Patent: November 19, 2019Assignee: Raytheon CompanyInventors: Ronald LaPat, Pierre Jean-Laurent, Anthony E. LoPresti, Harry Mieras, Thong Pham
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Patent number: 10472126Abstract: A collapsible metal box, in particular for transporting a material sensitive to creep, is provided. The box includes a base and two first and two second opposing side panels hinged to the base. At least one of the first side panels includes a retaining structure for maintaining the same in an upright position on the base while the second side panels are collapsed fully outwards.Type: GrantFiled: August 26, 2013Date of Patent: November 12, 2019Assignee: GROUPE ARNAUDInventors: Benoît Arnaud, Jean-François Baus, Jean-Laurent Bodolec, Vincent Marly
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Publication number: 20190338678Abstract: A support system (16) for a structural casing of a turbomachine (10), which comprises: a handling fitting (17) comprising a front edge (19) provided with one or more hole(s) (26) for receiving one or more screw(s) (24) for attachment to a flange (23) formed on the casing (10), a rear edge (20) provided with a cavity (32) for receiving a projecting boss (29) formed on the casing (10); a pair of jaws (31) for gripping the boss (29), that are mounted in the cavity (32); at least one screw (33) for adjusting the position of the jaws (31), mounted on the fitting (17) and engaging with at least one jaw (31).Type: ApplicationFiled: May 19, 2017Publication date: November 7, 2019Inventors: Patrick SULTANA, Sébastien Jean Laurent PRESTEL, Olivier RENON, Benoit Argémiro Matthieu DEBRAY, Guillaume SEVI
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Publication number: 20190321380Abstract: Compounds of Formula I: and their pharmaceutically acceptable salts are useful for the inhibition of HIV reverse transcriptase. The compounds may also be useful for the prophylaxis or treatment of infection by HIV and in the prophylaxis, delay in the onset or progression, and treatment of AIDS. The compounds and their salts can be employed as ingredients in pharmaceutical compositions, optionally in combination with other antiviral agents, immunomodulators, antibiotics or vaccines.Type: ApplicationFiled: December 19, 2017Publication date: October 24, 2019Applicants: Merck Sharp & Dohme Corp., Idenix Pharmaceuticals LLCInventors: Manuel de Lera Ruiz, Timothy J. Hartingh, Izzat Raheem, John Schreier, Jean-Laurent Paparin
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Patent number: 10449208Abstract: Compounds of Formula I: and pharmaceutically acceptable salts and co-crystals thereof are useful for the inhibition of HIV reverse transcriptase. The compounds may also be useful for the prophylaxis or treatment of infection by HIV and in the prophylaxis, delay in the onset or progression, and treatment of AIDS. The compounds and their salts can be employed as ingredients in pharmaceutical compositions, optionally in combination with other antiviral agents, immunomodulators, antibiotics or vaccines.Type: GrantFiled: August 22, 2017Date of Patent: October 22, 2019Assignees: Merck Sharp & Dohme Corp., Idenix Pharmaceuticals LLC.Inventors: Daniel Da Costa, Cyril B. Dousson, David Dukhan, Jean-Laurent Paparin, Houcine Rahali, Izzat Raheem
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Publication number: 20190262365Abstract: Compounds of Formula (I): (Formula (I)) and their pharmaceutically acceptable salts are useful for the inhibition of HIV reverse transcriptase. The compounds may also be useful for the prophylaxis or treatment of infection by HIV and in the prophylaxis, delay in the onset or progression, and treatment of AIDS. The compounds and their salts can be employed as ingredients in pharmaceutical compositions, optionally in combination with other antiviral agents, immunomodulators, antibiotics or vaccines.Type: ApplicationFiled: October 20, 2017Publication date: August 29, 2019Applicants: Merck Sharp & Dohme Corp., Idenix Pharmaceuticals LLC.Inventors: Jean-Laurent Paparin, Houcine Rahali, Aurélien Salanson, Daniel Da Costa, David Dukhan, Timothy J. Hartingh, Izzat Raheem, John Schreier
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Patent number: 10344610Abstract: A turbomachine module, comprising a mobile wheel rotatably mounted inside a housing of the module and surrounded by a sectorised sealing ring (18) that comprises an annular row of sectors, each ring sector comprising at least one circumferential hook that is configured to engage with an annular hooking rail of the housing, the module further comprising a sectorised protective annular shim (50) that is interposed between the hooks of the ring sectors and the rail of the housing and that comprises an annular row of sectors of shim, characterised in that the edges (60) of the circumferential ends of the sectors of shim are not aligned with the edges (58) of the circumferential ends of the ring sectors along the longitudinal axis of the module.Type: GrantFiled: August 4, 2015Date of Patent: July 9, 2019Assignee: SAFRAN AIRCRAFT ENGINESInventors: Cyril Loiseau, Alain Dominique Gendraud, Sebastien Jean Laurent Prestel
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Patent number: 10339709Abstract: A system and method may model physical geological structures. Seismic and geologic data may be accepted. A three-dimensional (3D) transformation may be generated between a 3D present day model having points representing present locations of the physical geological structures and a 3D past depositional model having points representing locations where the physical geological structures were originally deposited. An indication may be accepted to locally change the 3D transformation for a subset of sampling points in a first model of the models. The 3D transformation may be locally changed to fit the updated subset of sampling points. A locally altered or updated version of the first model and, e.g., second model, may be displayed where local changes to the first model are defined by the locally changed 3D transformation. The transformation may also be used to extract geobodies in the past depositional model.Type: GrantFiled: June 27, 2018Date of Patent: July 2, 2019Assignees: Emerson Paradigm Holding LLC, Jean-Laurent MALLETInventors: Jean-Laurent Mallet, Jean-Claude Dulac, Emmanuel Labrunye, Christophe Winkler, Laurent Deny
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Patent number: 10338252Abstract: A method, apparatus and system for, in a computing system, perturbing an initial three-dimensional (3D) geological model using a 3D vector field. A coherent 3D vector field including 3D vectors may be generated where each 3D vector of the 3D vector field is associated with a node of the initial 3D geological model and has a magnitude within a range of uncertainty of the node of the initial 3D geological model associated therewith. The coherent 3D vector field may be applied to the initial 3D geological model associated therewith to generate an perturbed 3D model. The perturbed 3D model may differ from the initial 3D geological model by a displacement defined by the 3D vector field associated with nodes having uncertain values. The perturbed 3D model may be displayed.Type: GrantFiled: July 6, 2016Date of Patent: July 2, 2019Assignees: Emerson Paradigm Holding LLCInventors: Jean-Laurent Mallet, Anne-Laure Tertois
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Patent number: 10330808Abstract: A device, system and method for performing a 3D interpolation in a 2D interpolation stage and a 1D interpolation stage to generate a refined geological-time. A 3D model may be obtained of a subsurface region defined by an initial geological-time in the past when particles in the subsurface region are determined to have been originally deposited. The stages of the 3D interpolation may include a 2D interpolation along one or more initial 2D reference horizon surfaces to generate one or more reshaped 2D reference horizon surfaces, and a 1D interpolation based on the initial geological-time along one or more 1D interpolation lines to generate a refined geological-time, wherein each 1D interpolation line is approximately orthogonal to the initial 2D reference horizon surfaces. The 3D model may be displayed according to the refined geological-time.Type: GrantFiled: June 23, 2017Date of Patent: June 25, 2019Assignees: Emerson Paradigm Holding LLCInventors: Jean-Laurent Mallet, Anne-Laure Tertois
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Patent number: 10331817Abstract: A method, apparatus and system for modeling a fault surface in a subsurface region. A direction may be determined in which a first portion of the subsurface region being on one side of the fault surface has moved relative to a second portion of the subsurface region being on the other side of the fault surface. A model of the fault surface may be generated having substantially no protrusions in the determined direction. A visualization of the model of the generated fault surface may be displayed.Type: GrantFiled: October 21, 2016Date of Patent: June 25, 2019Assignees: Emerson Paradigm Holding LLCInventors: Anne-Laure Tertois, Jean-Laurent Mallet, Laurent Deny, Jean-Claude Dulac