Patents by Inventor Jean-Luc Montchamp

Jean-Luc Montchamp has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROCESS OF PREPARING CYCLIC PHOSPHONATE ESTER, CYCLIC PHOSPHONATE ESTER PREPARED THEREFROM AND INDUSTRIAL APPLICATIONS CONTAINING THE SAME
    Publication number: 20170174714
    Abstract: There is provided herein a process for preparing cyclic phosphonate ester comprising reacting a glycol with at least one of phosphonic acid and phosphinic acid in the presence of a solvent. There is also provided a flame retardant comprising the cyclic phosphonate ester and industrial applications containing a flame retardant effective amount of the cyclic phosphonate ester.
    Type: Application
    Filed: March 12, 2015
    Publication date: June 22, 2017
    Inventors: Jean-luc Montchamp, Lucie Prost
  • Synthesis of H-phosphonate intermediates and their use in preparing the herbicide glyphosate
    Patent number: 9035083
    Abstract: The esterfication of hypophosphorous acid is followed by reaction with another molecule of alcohol under the action of a nickel catalyst to provide a green method for the preparation of H-phosphonate diesters. This method avoids the need for any stoichiometric chlorine unlike those based on phosphorous trichloride.
    Type: Grant
    Filed: March 21, 2014
    Date of Patent: May 19, 2015
    Assignee: Texas Christian University
    Inventors: Jean-Luc Montchamp, Henry C. Fisher
  • Sythesis of P-chiral compounds
    Patent number: 8877957
    Abstract: Shown is the preparation and subsequent elaboration of P-chiral compounds that can be used as a building block for many P-chiral ligands used, for example, in asymmetric catalytic reactions. Specifically, a synthesis is shown for RP(O)(OR*)CH2OH, with R=H, Ph, aryl, alkyl, and R*=menthol (and other chiral alcohol-derived moieties), especially HP(O)(OMen)CH2OH (Men=L-menthol). This versatile building block is easily synthesized via reaction of inexpensive starting materials, H3PO2, menthol as the chiral auxiliary, and paraformaldehyde.
    Type: Grant
    Filed: June 7, 2013
    Date of Patent: November 4, 2014
    Assignee: Texas Christian University
    Inventors: Jean-Luc Montchamp, Olivier Berger
  • Synthesis of H-Phosphonate Intermediates and Their Use in Preparing the Herbicide Glyphosate
    Publication number: 20140303394
    Abstract: The esterfication of hypophosphorous acid is followed by reaction with another molecule of alcohol under the action of a nickel catalyst to provide a green method for the preparation of H-phosphonate diesters. This method avoids the need for any stoichiometric chlorine unlike those based on phosphorous trichloride.
    Type: Application
    Filed: March 21, 2014
    Publication date: October 9, 2014
    Applicant: Texas Christian University
    Inventors: Jean-Luc Montchamp, Henry C. Fisher
  • Sythesis of P-Chiral Compounds
    Publication number: 20130331594
    Abstract: Shown is the preparation and subsequent elaboration of P-chiral compounds that can be used as a building block for many P-chiral ligands used, for example, in asymmetric catalytic reactions. Specifically, a synthesis is shown for RP(O)(OR*)CH2OH, with R=H, Ph, aryl, alkyl, and R*=menthol (and other chiral alcohol-derived moieties), especially HP(O)(OMen)CH2OH (Men=L-menthol). This versatile building block is easily synthesized via reaction of inexpensive starting materials, H3PO2, menthol as the chiral auxiliary, and paraformaldehyde.
    Type: Application
    Filed: June 7, 2013
    Publication date: December 12, 2013
    Inventors: Jean-Luc Montchamp, Olivier Berger
  • Bis-H-phosphinic acid derivatives as precursors to therapeutic bisphosphonates and uses thereof
    Patent number: 6781011
    Abstract: A novel class of compounds, i.e., 1,1-bis-H-phosphinates (or 1,1-bis-H-phosphinic acid derivatives) are provided. Also provided are novel methods for producing 1,1-bis-H-phosphinates and 1,1-bis-H-phosphinate conjugates. These compounds and conjugates are used are precursors of bisphosphonates and bisphosphonate conjugates, respectively, or as prodrugs directly for treating bone-related and various other diseases.
    Type: Grant
    Filed: December 13, 2002
    Date of Patent: August 24, 2004
    Assignee: Texas Christian University
    Inventors: Jean-Luc Montchamp, Sylvine Deprele
  • BIS-H-PHOSPHINIC ACID DERIVATIVES AS PRECURSORS TO THERAPEUTIC BISPHOSPHONATES AND USES THEREOF
    Publication number: 20040116673
    Abstract: A novel class of compounds, i.e., 1,1-bis-H-phosphinates (or 1,1-bis-H-phosphinic acid derivatives) are provided. Also provided are novel methods for producing 1,1-bis-H-phosphinates and 1,1-bis-H-phosphinate conjugates. These compounds and conjugates are used as precursors of bisphosphonates and bisphosphonate conjugates, respectively, or as prodrugs directly for treating bone-related and various other diseases.
    Type: Application
    Filed: December 13, 2002
    Publication date: June 17, 2004
    Applicant: Texas Christian University
    Inventors: Jean-Luc Montchamp, Sylvine Deprele