Abstract: Systems and methods treat plasma carrying contaminants and cellular matter that are capable of entraining contaminants. The systems and methods separate cellular matter from the plasma by filtration, thereby removing contaminants entrained within the cellular matter. The system and methods add to the plasma a photoactive material. The systems and methods emit radiation at a selected wavelength into the plasma to activate the photoactive material and thereby eradicate the contaminant that is free of entrainment by cellular matter.

Abstract: Systems and methods treat plasma carrying contaminants and cellular matter that are capable of entraining contaminants. The systems and methods separate cellular matter from the plasma by filtration, thereby removing contaminants entrained within the cellular matter. The system and methods add to the plasma a photoactive material. The systems and methods emit radiation at a selected wavelength into the plasma to activate the photoactive material and thereby eradicate the contaminant that is free of entrainment by cellular matter.

Abstract: System and methods treat plasma carrying contaminants and cellular matter that are capable of entraining contaminants. The systems and methods separate cellular matter from the plasma by filtration, thereby removing contaminants entrained within the cellular matter. The system and methods add to the plasma a photoactive material. The systems and methods emit radiation at a selected wavelength into the plasma to activate the photoactive material and thereby eradicate the contaminant that is free of entrainment by cellular matter.

Abstract: Systems and methods treat biological fluids carrying contaminants by photoactivating materials mixed with the fluids. The systems and methods quantify the photoreactions that occur in a manner that permits correlation with clinical results.

Abstract: A vessel holds a liquid content for exposure to prescribed light energy. The vessel has a region transparent to the prescribed light energy. The liquid content of the vessel includes a solution comprising a material undergoing reduction oxidation as a result of exposure to the prescribed light energy, and a reducing agent for the photoactive material. A device measures optical absorbance of the vessel and the liquid content. The device operates in a first instance to measure a first optical absorbance value before exposing the vessel and the liquid content to the prescribed light energy. The device also operates in a second instance to measure a second optical absorbance value after exposing the vessel and the liquid content to the prescribed light energy, to obtain a difference between the first and second optical absorbance values. The difference comprises an illumination characteristic for the vessel with respect to the prescribed light energy.

Abstract: A port and closure for a container is provided. The closure includes an interface layer for bonding the closure to the port. The bond strength of the interface layer to the closure is less than the bond strength of the interface layer to the port. The closure being removed from the port by delaminating the interface layer from the port.

Abstract: There is disclosed herein a flow-through medical filter element which includes surface or depth filter media and a frame-like structure for supporting and positioning the media. The frame-like structure is a molded member which includes a ring-like inlet, a fluid-impervious terminal end spaced from the inlet and a plurality of rib-like members which extend between and interconnect the inlet end and terminal end. The inlet end includes internally-extending pleat-supporting projections and the terminal end has complementary externally-extending pleat-supporting shoulders. The frame-like structure is symmetrical about an axial plane which includes the mold parting line. The external shoulders are formed at angles which permits separation of a mold along the parting line and release of the part. The filter media also includes longitudinal pleats and is secured at its ends to the pleat-supporting projections associated with the inlet end and to the external pleat-supporting shoulders at the terminal end.