Patents by Inventor Jean-Marc DuFour

Jean-Marc DuFour has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bifunctional chelating compounds containing hydroxamic acid residues
    Patent number: 7238339
    Abstract: New types of hydroxamic acid-based bifunctional chelators are provided. These chelators are designed to chelate metal ions that can be detected either by their paramagnetic or radioactive properties. Conjugation with peptides or protein can be achieved by the presence of a linker moiety in the molecular structure of these chelators.
    Type: Grant
    Filed: August 4, 2003
    Date of Patent: July 3, 2007
    Assignee: DRAXIS Specialty Pharmaceuticals Inc.
    Inventor: Jean-Marc DuFour
  • Novel bifunctional chelating compounds containing hydroxamic acid residues
    Publication number: 20040086460
    Abstract: New types of hydroxamic acid-based bifunctional chelators are provided. These chelators are designed to chelate metal ions that can be detected either by their paramagnetic or radioactive properties. Conjugation with peptides or protein can be achieved by the presence of a linker moiety in the molecular structure of these chelators.
    Type: Application
    Filed: August 4, 2003
    Publication date: May 6, 2004
    Inventor: Jean-Marc DuFour
  • Bifunctional chelating compounds containing hydroxamic acid residues
    Patent number: 6623721
    Abstract: New types of hydroxamic acid-based bifunctional chelators are provided. These chelators are designed to chelate metal ions that can be detected either by their paramagnetic or radioactive properties. Conjugation with peptides or protein can be achieved by the presence of a linker moiety in the molecular structure of these chelators.
    Type: Grant
    Filed: December 18, 2000
    Date of Patent: September 23, 2003
    Assignee: Draximage, Inc.
    Inventors: Richard J. Flanagan, Jean-Marc Dufour
  • Novel bifunctional chelating compounds containing hydroxamic acid residues
    Publication number: 20020076377
    Abstract: New types of hydroxamic acid-based bifunctional chelators are provided. These chelators are designed to chelate metal ions that can be detected either by their paramagnetic or radioactive properties. Conjugation with peptides or protein can be achieved by the presence of a linker moiety in the molecular structure of these chelators.
    Type: Application
    Filed: December 18, 2000
    Publication date: June 20, 2002
    Inventors: Richard J. Flanagan, Jean-Marc Dufour
  • N.sub.3 S.sub.2 chelating ligands optionally radiolabelled with Tc or Re, useful for diagnostic or therapeutic applications
    Patent number: 5632969
    Abstract: Novel N.sub.3 S.sub.2 chelating ligands can be chelated to a radiodetectable element, Tc or Re, and are useful for radiolabeling peptides. A group of peptides especially useful are somatostatin derivatives which are valuable of the selective detection or treatment of tumors with somatostatin receptors.
    Type: Grant
    Filed: October 13, 1994
    Date of Patent: May 27, 1997
    Assignee: Merck & Co., Inc.
    Inventors: Richard J. Flanagan, Jean-Marc Dufour, Keith T. Hogan
  • TC or RE radionuclide labelled chelate, hexapeptide complexes useful for diagnostic or therapeutic applications
    Patent number: 5556939
    Abstract: Technetium or rhenium radionuclide labelled chelate-hexapeptide complexes are useful for the selective detection or treatment of tumors with somatostatin receptors. In particular, compounds of formula: ##STR1## (wherein R, R.sup.1, R.sup.3 and A are as defined herein) incorporating an N3S2 chelate may be labelled with a radionuclide. The resulting complexes are useful as radioimaging agents or as radiopharmaceuticals for the treatment of certain tumors.
    Type: Grant
    Filed: October 13, 1994
    Date of Patent: September 17, 1996
    Assignee: Merck Frosst Canada, Inc.
    Inventors: Richard J. Flanagan, Jean-Marc Dufour, Keith T. Hogan
  • High affinity chelates containing isothiocyanate groups, useful for coupling with peptides and proteins
    Patent number: 5539138
    Abstract: The ligands HBED-SCN, HBPD-SCN, and HTDD-SCN are provided which have enhanced ease of reaction with peptides or proteins and which are suitable for chelating with radioisoptopes, especially Indium-.sup.III and Gallium-.sup.67.
    Type: Grant
    Filed: July 28, 1994
    Date of Patent: July 23, 1996
    Assignee: Merck Frosst Canada, Inc.
    Inventors: Richard J. Flanagan, Keith T. Hogan, Jean-Marc Dufour, F. Peter Charleson