Patents by Inventor Jean-Pierre Bastart

Jean-Pierre Bastart has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of 7-hydroxytaxanes
    Patent number: 5750738
    Abstract: This invention relates to a process for the preparation of 7-hydroxy taxanes of general formula (I) from 7-trialkylsilyl taxanes of general formula (II), wherein R.sub.1 is hydrogen, alkoxy, acyloxy, or alkoxyacetoxy, and Z is a hydrogen atom or a radical of general formula (III), wherein R.sub.2 is an optionally substituted benzyl radical or an R'.sub.2 --O--CO-- radical wherein R'.sub.2 is an alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, bicycloalkyl, optionally substituted phenyl or heterocyclyl radical, R.sub.3 is an aromatic alkyl, alkenyl, alkynyl, cycloalyl, phenyl, naphthyl or heterocyclyl radical and either R.sub.4 is a hydrogen atom and R.sub.5 is a hydroxyl function protecting group, or R.sub.4 and R.sub.5 together form a saturated 5- or 6-membered heterocylic ring. In general formula (II), each R, which are the same or different, is an alkyl radical optionally substituted by a phenyl radical.
    Type: Grant
    Filed: October 3, 1996
    Date of Patent: May 12, 1998
    Assignee: Rhone-Poulenc Rorer S.A.
    Inventors: Jean-Pierre Bastart, Jean-Dominique Boursat, Alain Commercon, Jean-Pierre Leconte
  • Compositions containing taxane derivatives
    Patent number: 5750561
    Abstract: The invention provides new compositions containing taxane derivatives, consisting of solutions of such derivatives in a solvent mixture composed of ethanol and polysorbate. These compositions are used to prepare perfusions.
    Type: Grant
    Filed: April 12, 1995
    Date of Patent: May 12, 1998
    Assignee: Rhone-Poulenc Rorer, S.A.
    Inventors: Jean-Pierre Bastart, Thierry Dupechez, Jean-Louis Fabre
  • Compositions containing taxane derivatives
    Patent number: 5714512
    Abstract: This invention relates to compositions containing taxane derivatives, consisting of a solution of such derivatives in a surfactant. These compositions can be used to prepare perfusion solutions.
    Type: Grant
    Filed: December 7, 1995
    Date of Patent: February 3, 1998
    Assignee: Rhone-Poulenc Rorer, S.A.
    Inventors: Jean-Pierre Bastart, Thierry Dupechez, Jean-Louis Fabre
  • Compositions containing taxane derivatives
    Patent number: 5698582
    Abstract: This invention relates to compositions containing taxane derivatives, consisting of a solution of such derivatives in a surfactant. These compositions can be used to prepare perfusion solutions.
    Type: Grant
    Filed: March 3, 1995
    Date of Patent: December 16, 1997
    Assignee: Rhone-Poulenc Rorer S.A.
    Inventors: Jean-Pierre Bastart, Thierry Dupechez, Jean-Louis Fabre
  • Process for preparing 7-trialkylsilyl baccatin III
    Patent number: 5670658
    Abstract: The present invention relates to a novel process for the preparation of 7-trialkylsilylbaccatin III of general formula: ##STR1## in which the symbols R, which may be identical or different, represent alkyl radicals containing 1 to 4 carbon atoms which are optionally substituted with a phenyl radical, starting with 10-deacetylbaccatin III of formula: ##STR2## In the general formula (I), each of the symbols R preferably represents a straight or branched alkyl radical containing 1 to 4 carbon atoms. Even more particularly, each of the symbols R represents an ethyl radical.
    Type: Grant
    Filed: October 3, 1996
    Date of Patent: September 23, 1997
    Assignee: Rhone-Poulenc Rorer S.A.
    Inventors: Jean-Pierre Bastart, Jean-Pierre Leconte
  • Pristinaymcinia or virginiamycin derivatives and their preparation
    Patent number: 5304642
    Abstract: This invention relates to a process for preparing synergistic derivatives of formula (I), in which Y is hydrogen or dimethylamino, from pristinamycin I.sub.A or from virginiamycin, via a Mannich base, followed by elimination of the amine introduced.
    Type: Grant
    Filed: July 2, 1992
    Date of Patent: April 19, 1994
    Assignee: Rhone Poulenc Sante
    Inventors: Jean-Pierre Bastart, Jean-Marc Paris, Xavier Radisson
  • New process for the preparation of pristinamycin II.sub.B derivatives
    Patent number: 4775753
    Abstract: Pristinamycin II.sub.
    Type: Grant
    Filed: July 7, 1987
    Date of Patent: October 4, 1988
    Assignee: Rhone-Poulenc Sante
    Inventors: Jean-Claude Barriere, Jean-Pierre Bastart, Jean-Marc Paris