Patents by Inventor Jean-Pierre Sachetto
Jean-Pierre Sachetto has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20170056354Abstract: A pharmaceutical formulation comprising at least one omega-3 polyunsaturated fatty acid in free acid form or a pharmacologically acceptable derivative thereof is contained in a soft gelatin capsule characterised in that the capsule comprises gelatin extracted by an extraction process comprising acid pre-treatment of a collagen source. One advantage of the present invention over a soft to gelatin capsule containing the same formulation but comprising gelatin extracted by an extraction process comprising alkali pre-treatment of the collagen source is that the present invention does not harden significantly over time and thus has a longer shelf life.Type: ApplicationFiled: November 14, 2016Publication date: March 2, 2017Applicant: Chrysalis Pharma AGInventors: Jean-Pierre SACHETTO, Roly BUFTON, Thomas BUSER
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Patent number: 9132112Abstract: A pharmaceutical formulation comprising at least one omega-3 polyunsaturated fatty acid in free acid form or a pharmacologically acceptable derivative thereof is contained in a soft gelatin capsule characterized in that the capsule comprises gelatin extracted by an extraction process comprising acid pre-treatment of a collagen source. One advantage of the present invention over a soft gelatin capsule containing the same formulation but comprising gelatin extracted by an extraction process comprising alkali pre-treatment of the collagen source is that the present invention does not harden significantly over time and thus has a longer shelf life.Type: GrantFiled: April 22, 2014Date of Patent: September 15, 2015Assignee: CHYSALIS PHARMA AGInventors: Jean-Pierre Sachetto, Roly Bufton, Thomas Buser
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Publication number: 20150238430Abstract: A pharmaceutical formulation comprising at least one omega-3 polyunsaturated fatty acid in free acid form or a pharmacologically acceptable derivative thereof is contained in a soft gelatin capsule characterised in that the capsule comprises gelatin extracted by an extraction process comprising acid pre-treatment of a collagen source. One advantage of the present invention over a soft gelatin capsule containing the same formulation but comprising gelatin extracted by an extraction process comprising alkali pre-treatment of the collagen source is that the present invention does not harden significantly over time and thus has a longer shelf life.Type: ApplicationFiled: April 29, 2015Publication date: August 27, 2015Applicant: Chrysalis Pharma AGInventors: Jean-Pierre SACHETTO, Roly BUFTON, Thomas BUSER
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Patent number: 9012501Abstract: A pharmaceutical formulation comprising at least one omega-3 polyunsaturated fatty acid in free acid form or a pharmacologically acceptable derivative thereof is contained in a soft gelatin capsule characterized in that the capsule comprises gelatin extracted by an extraction process comprising acid pre-treatment of a collagen source. One advantage of the present invention over a soft to gelatin capsule containing the same formulation but comprising gelatin extracted by an extraction process comprising alkali pre-treatment of the collagen source is that the present invention does not harden significantly over time and thus has a longer shelf life.Type: GrantFiled: January 4, 2013Date of Patent: April 21, 2015Assignee: Chrysalis Pharma AGInventors: Jean-Pierre Sachetto, Roly Bufton, Thomas Buser
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Publication number: 20140228437Abstract: A pharmaceutical formulation comprising at least one omega-3 polyunsaturated fatty acid in free acid form or a pharmacologically acceptable derivative thereof is contained in a soft gelatin capsule characterised in that the capsule comprises gelatin extracted by an extraction process comprising acid pre-treatment of a collagen source. One advantage of the present invention over a soft gelatin capsule containing the same formulation but comprising gelatin extracted by an extraction process comprising alkali pre-treatment of the collagen source is that the present invention does not harden significantly over time and thus has a longer shelf life.Type: ApplicationFiled: April 22, 2014Publication date: August 14, 2014Applicant: Chrysalis Pharma AGInventors: Jean-Pierre SACHETTO, Roly BUFTON, Thomas BUSER
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Publication number: 20130123362Abstract: A pharmaceutical formulation comprising at least one omega-3 polyunsaturated fatty acid in free acid form or a pharmacologically acceptable derivative thereof is contained in a soft gelatin capsule characterised in that the capsule comprises gelatin extracted by an extraction process comprising acid pre-treatment of a collagen source. One advantage of the present invention over a soft to gelatin capsule containing the same formulation but comprising gelatin extracted by an extraction process comprising alkali pre-treatment of the collagen source is that the present invention does not harden significantly over time and thus has a longer shelf life.Type: ApplicationFiled: January 4, 2013Publication date: May 16, 2013Inventors: Jean-Pierre Sachetto, Roly Button, Thomas Buser
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Patent number: 8383678Abstract: A pharmaceutical formulation comprising at least one omega-3 polyunsaturated fatty acid in free acid form or a pharmacologically acceptable derivative thereof is contained in a soft gelatin capsule characterized in that the capsule comprises gelatin extracted by an extraction process comprising acid pre-treatment of a collagen source. One advantage of the present invention over a soft gelatin capsule containing the same formulation but comprising gelatin extracted by an extraction process comprising alkali pre-treatment of the collagen source is that the present invention does not harden significantly over time and thus has a longer shelf life.Type: GrantFiled: January 5, 2011Date of Patent: February 26, 2013Assignee: Chrysalis Pharma AGInventors: Jean-Pierre Sachetto, Roly Bufton, Thomas Buser
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Patent number: 7960370Abstract: A pharmaceutical formulation comprising at least one omega-3 polyunsaturated fatty acid in free acid form or a pharmacologically acceptable derivative thereof is contained in a soft gelatin capsule characterized in that the capsule comprises gelatin extracted by an extraction process comprising acid pre-treatment of a collagen source. One advantage of the present invention over a soft gelatin capsule containing the same formulation but comprising gelatin extracted by an extraction process comprising alkali pre-treatment of the collagen source is that the present invention does not harden significantly over time and thus has a longer shelf life.Type: GrantFiled: February 7, 2005Date of Patent: June 14, 2011Inventors: Jean-Pierre Sachetto, Roly Bufton, Thomas Buser
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Publication number: 20110097394Abstract: A pharmaceutical formulation comprising at least one omega-3 polyunsaturated fatty acid in free acid form or a pharmacologically acceptable derivative thereof is contained in a soft gelatin capsule characterised in that the capsule comprises gelatin extracted by an extraction process comprising acid pre-treatment of a collagen source. One advantage of the present invention over a soft gelatin capsule containing the same formulation but comprising gelatin extracted by an extraction process comprising alkali pre-treatment of the collagen source is that the present invention does not harden significantly over time and thus has a longer shelf life.Type: ApplicationFiled: January 5, 2011Publication date: April 28, 2011Inventors: Jean-Pierre Sachetto, Roly Bufton, Thomas Buser
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Publication number: 20090018125Abstract: Polyunsaturated fatty acid (“PUFA”) or a pharmacologically acceptable salt or derivative thereof (such as EPA and/or DHA) is used in combination with at least one of an immunosuppressive agent or an antineoplastic agent, said agent(s) having at least one amino acid residue, or a pharmacologically acceptable salt or derivative thereof (such as methotrexate or cyclosporin) in the treatment of conditions involving acutely or chronically inadequate immune response. Specific conditions that may be treated include chronic inflammatory diseases (e.g. Crohn's disease and ulcerative colitis) and tumour diseases (e.g. bowel cancer and prostate cancer). One advantage of preferred embodiments of the invention is that bioavailability of immunosuppressive or antineoplastic agents is increased.Type: ApplicationFiled: June 15, 2005Publication date: January 15, 2009Applicant: Tillotts Pharma AGInventors: Ulrich Mittmann, Jean-Pierre Sachetto
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Patent number: 7341741Abstract: A polysaccharide selected from xanthan gum and HPMC is used for the treatment or prophylaxis of IBD, especially Crohn's Disease, left-sided ulcerative colitis or pouchitis.Type: GrantFiled: September 25, 1998Date of Patent: March 11, 2008Inventors: Jean-Pierre Sachetto, William Jeffery Sandborn, William John Tremaine
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Publication number: 20070269507Abstract: A pharmaceutical formulation comprising at least one omega-3 polyunsaturated fatty acid in free acid form or a pharmacologically acceptable derivative thereof is contained in a soft gelatin capsule characterised in that the capsule comprises gelatin extracted by an extraction process comprising acid pre-treatment of a collagen source. One advantage of the present invention over a soft gelatin capsule containing the same formulation but comprising gelatin extracted by an extraction process comprising alkali pre-treatment of the collagen source is that the present invention does not harden significantly over time and thus has a longer shelf life.Type: ApplicationFiled: February 7, 2005Publication date: November 22, 2007Applicant: Tillotts Pharma AGInventors: Jean-Pierre Sachetto, Roly Bufton, Thomas Buser
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Publication number: 20070219271Abstract: Polyunsaturated fatty acid (“PUFA”) or a pharmacologically acceptable salt or derivative thereof (such as EPA and/or DHA) is used in combination with at least one of an immunosuppressive agent or an antineoplastic agent or a pharmacologically acceptable salt or derivative thereof in the treatment of conditions involving acutely or chronically inadequate immune response by topical application of said active agents to at least a portion of the intestinal mucosa. Specific conditions that may be treated include chronic inflammatory disease (e.g. Chrohn's disease and ulcerative colitis) and tumour disease (e.g. bowel cancer and prostate cancer). One advantage of preferred embodiments of the invention is that bioavailability of immunosuppressive or antineoplastic agents is increased.Type: ApplicationFiled: June 15, 2005Publication date: September 20, 2007Applicant: Tillotts Pharma AGInventors: Ulrich Mittmann, Jean-Pierre Sachetto
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Patent number: 6004546Abstract: An essentially water-insoluble compound of bismuth and polyacrylic acid disperses well in the bowel and forms a good mucoadhesive covering of the bowel wall. Thus in patients with inflammatory bowel disease the bismuth is held in intimate contact to the inflamed tissue of the bowel. Two processes are provided for preparing said water-insoluble compounds.Type: GrantFiled: May 14, 1999Date of Patent: December 21, 1999Assignee: Medeva Europe LimitedInventor: Jean-Pierre Sachetto
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Patent number: 5972310Abstract: An aqueous foamable composition is provided having a delayed foaming action on expulsion from a pressurized container. The composition comprises a major amount of water, a water-immiscible liquified gas foaming agent, at least one foam-stabilizing and emulsifying surfactant, and a water-soluble polymer. The composition is particularly useful for rectal or vaginal administration of pharmaceuticals.Type: GrantFiled: May 29, 1998Date of Patent: October 26, 1999Assignee: Tillotts Pharma AGInventor: Jean-Pierre Sachetto
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Patent number: 5759520Abstract: An aqueous foamable composition is provided having a delayed foaming action on expulsion from a pressurized container. The composition comprises a major amount of water, a water-immiscible liquefied gas foaming agent, at least one foam-stabilizing and emulsifying surfactant, and a water-soluble polymer. The composition is particularly useful for rectal or vaginal administration of pharmaceuticals.Type: GrantFiled: February 24, 1997Date of Patent: June 2, 1998Assignee: Tillotts Pharma AGInventor: Jean-Pierre Sachetto
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Patent number: 5587412Abstract: According to the present invention there is provided a composition as obtained from a melt comprising esterified starch, preferably having an amylose content of at least about 50% by weight with respect to that of the starch, and being substituted to a degree of at least about 1.5, preferably from about 1.8 to about 2.9. The starch ester may be of the kind obtained by reaction of a mixed acid anhydride with starch.Type: GrantFiled: February 6, 1995Date of Patent: December 24, 1996Assignee: National Starch and Chemical Investment Holding CorporationInventors: Gerd Borchers, Ingo Dake, Albrecht Dinkelaker, Jean-Pierre Sachetto, Richard Zdrahala, Stephen Rimsa, Gary Loomis, Paul Tatarka, Olivier Mauzac
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Patent number: 5095054Abstract: A thermoplastic polymer composition comprising:(a) a destructurized starch, and either(b) an effective amount of at least one compound selected from the following: (1) a polymer which contains at least two different types of functional groups, one of said types of these groups being hydroxyl groups; (2) at least one polymer which does not contain hydroxyl groups and is selected from the group consisting of polymers which contain at least two types of functional groups bound to the same molecule one type of these groups being carboxylate groups; (3) at least one polymer selected from the group consisting of polymers which contain tertiary amino groups and/or salts thereof and/or quaternary ammonium groups; (4) at least one polymer selected from the group of polysaccharides which have been chemically modified to contain added hydroxyalkyl groups and/or contain alkyl ether groups, and/or contain ester groups; (5) at least one compound selected from the group consisting of copolymers of vinyl pyrrolidone; (6) atType: GrantFiled: June 18, 1990Date of Patent: March 10, 1992Assignee: Warner-Lambert CompanyInventors: Gustav Lay, Johannes Rehm, Robert F. Stepto, Markus Thoma, Jean-Pierre Sachetto, David J. Lentz, Jakob Silbiger
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Destructurized starch essentially containing no bridged phosphate groups and process for making same
Patent number: 4900361Abstract: The invention refers to a process for obtaining a melt of destruction starch containing a finite amount of electrolytes comprising:A. providing a starch material containing free electrolytes and/or bound phosphate salts,B. removing partially or wholly the free electrolytes and/or the metallic cations from the phosphate groups of the starch,C. optionally replacing a part or all of the free H.sup.+ -ions of the free phosphate groups with metallic monovalent and/or polyvalent cations,D. conditioning the obtained starch material to a water content of 10 to 25% by weight calculated on the basis of starch and water,E. heating said starch/water composition at elevated pressure to a temperature sufficient to essentially destructure the starch while maintaining said water content until a melt of destructurized starch is formed.The invention further refers to the process ofF. cooling said melt (as obtained under E.Type: GrantFiled: June 20, 1988Date of Patent: February 13, 1990Assignee: Warner-Lambert CompanyInventors: Jean-Pierre Sachetto, Robert F. T. Stepto, Heinz Zeller -
Patent number: 4665158Abstract: Dehydrated protein materials are treated with gaseous HCl without temperature control, the reaction temperature being susceptible to reach, momentarily, 150.degree. C. Then the material thus treated is degassed and, after drying, a non hygroscopic powder usable in the food industry or in the pharmaceutical industry is obtained.Type: GrantFiled: May 30, 1985Date of Patent: May 12, 1987Assignee: Battelle Memorial InstituteInventors: Jean-Michel Armanet, Claude Giddey, Jean-Pierre Sachetto