Patents by Inventor Jean Schmid
Jean Schmid has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240101345Abstract: A container system (10, 110) and a method for calculating (S6) a current fill status (64_CURR) of a container (30) using a plurality of presence sensor interactions (34) is disclosed. The container system (10, 110) comprises a presence sensor arrangement (32, 132) for calculating (S6) the plurality of presence sensor interactions (34) with the container (30); a local counting unit (40) for recording (S2) numbers of the plurality of presence sensor interactions (34) as presence sensor interaction data (36); and a local communication unit (60) for transmitting (S3) the presence sensor interaction data (36) to a remote processing unit (55) for calculating (S6) the current fill status (64 CURR).Type: ApplicationFiled: November 24, 2021Publication date: March 28, 2024Inventors: Jean-Nicolas Tisserant, Janusz Schinke, Alexey Sizov, Kevin Schmid
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Patent number: 11923163Abstract: A fuse element for a fuse with an integrated measurement function, includes a first receiving area in an embodiment, for receiving a melting conductor of the fuse, delimited in the length direction of the fuse by a closure element and in a direction orthogonal to the length direction by the fuse element. Further, in an embodiment, the fuse element has a second receiving area, physically separated from the first receiving area, for receiving a measuring device of the fuse. The second receiving area is designed to receive the measuring device in a wall section of the fuse element. The second receiving area formed in the fuse element protects the measuring device arranged therein against interfering environmental influences. The measuring device is used to ascertain the electric current flowing through the fuse directly on the fuse.Type: GrantFiled: December 3, 2019Date of Patent: March 5, 2024Assignee: Siemens AktiengesellschaftInventors: Thomas Hochmuth, Robert Huettinger, Jean-Mary Martel, Christian Rohrwild, Adolf Schmid, Volker Seefeld
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Patent number: 7521552Abstract: There is provided a process for the preparation of substituted amino alcohols HO—(CH2)n—NR1R2 from haloalcohols HO—(CH2)n—X, where X is Cl, Br or I, by reaction with an amine HNR1R2, in water as solvent at a temperature range of about 20° C. to about 90° C. optionally in the presence of a catalytic amount of an iodide source metal iodides. The haloalcohols are useful in the preparation of 6-[(substituted)phenyl]-triazolopyrimidine compounds which are useful in the treatment of cancer.Type: GrantFiled: December 8, 2004Date of Patent: April 21, 2009Assignee: WyethInventors: Yanzhong Wu, Arkadiy Rubezhov, Jean Schmid, Jay Thomas Afragola
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Publication number: 20090082591Abstract: Methods for preparing substituted phenylsulfonamide compounds of the following structure are provided: or a pharmaceutically acceptable salt thereof, wherein, R1-R7 are defined herein. Also provided are methods for preparing compounds of the following structure: wherein, R9, m, n, p, r, and s are defined herein.Type: ApplicationFiled: December 8, 2008Publication date: March 26, 2009Applicant: WyethInventors: Asaf Ragim Alimardanov, Jean Schmid, Jay Thomas Afragola, Gulnaz Khafizova
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Patent number: 7501423Abstract: The invention provides 6-chloro-5-{2,6-difluoro-4-[3-(methylamino)propoxy]phenyl}-2-pyrazin-2-yl-N-[(1S)-2,2,2-trifluoro-1-methylethyl]pyrimidin-4-amine hemifumarate which is a tubulin inhibitor useful in the treatment of cancer and processes of making said hemifumarate.Type: GrantFiled: June 4, 2007Date of Patent: March 10, 2009Assignee: WyethInventors: David Michael Blum, Yanzhong Wu, Jean Schmid, Timothy John Doyle, Jay Thomas Afragola
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Patent number: 7476762Abstract: Methods for preparing substituted phenylsulfonamide compounds of the following structure are provided: or a pharmaceutically acceptable salt thereof, wherein, R1-R7 are defined herein. Also provided are methods for preparing compounds of the following structure: wherein, R9, m, n, p, r, and s are defined herein.Type: GrantFiled: April 19, 2007Date of Patent: January 13, 2009Assignee: WyethInventors: Asaf Ragim Alimardanov, Jean Schmid, Jay Thomas Afragola, Gulnaz Khafizova
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Patent number: 7396835Abstract: The present invention provides a process for the preparation of 6-[(substituted)phenyl]-triazolopyrimidine dicarboxylic acid salt and as a hydrated salt having the structural formula (I) wherein: R1 is CF3 or C2F5; R2 is H or C1-C3 alkyl; n is an integer of 2, 3, or 4; X is Cl or Br; R3 and R4 are each independently H or C1-C3 alkyl; or R3 and R4 when optionally taken together with the nitrogen atom to which each is attached form a 4 to 6 membered saturated heterocyclic ring having 1-2 nitrogen atoms and 0-1 oxygen atoms or 0-1 sulfur atoms, and optionally substituted with R5; R5 is C1-C3 alkyl; wherein the dotted line is an optional bond.Type: GrantFiled: December 8, 2004Date of Patent: July 8, 2008Assignee: WyethInventors: Yanzhong Wu, Jean Schmid, Jay Thomas Afragola, David Blum, Semiramis Ayral-Kaloustian
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Publication number: 20070299083Abstract: The present invention relates to hydrochloric acid salt and crystalline forms of the 5-HT1A binding agent 6-methoxy-8-[4-(1-(5-fluoro)-quinolin-8-yl-piperidin-4-yl)-piperazin-1-yl]-quinoline, as well as pharmaceutical compositions thereof, and methods of use thereof.Type: ApplicationFiled: June 8, 2007Publication date: December 27, 2007Applicant: WyethInventors: Jean Schmid, James Bicksler
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Publication number: 20070249723Abstract: Methods for preparing substituted phenylsulfonamide compounds of the following structure are provided: or a pharmaceutically acceptable salt thereof, wherein, R1-R7 are defined herein. Also provided are methods for preparing compounds of the following structure: wherein, R9, m, n, p, r, and s are defined herein.Type: ApplicationFiled: April 19, 2007Publication date: October 25, 2007Applicant: WyethInventors: Asaf Ragim Alimardanov, Jean Schmid, Jay Thomas Afragola, Gulnaz Khafizova
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Publication number: 20070249627Abstract: The invention provides 6-chloro-5-{2,6-difluoro-4-[3-(methylamino)propoxy]phenyl}-2-pyrazin-2-yl-N-[(1S)-2,2,2-trifluoro-1-methylethyl]pyrimidin-4-amine hemifumarate which is a tubulin inhibitor useful in the treatment of cancer and processes of making said hemifumarate.Type: ApplicationFiled: June 4, 2007Publication date: October 25, 2007Applicant: WyethInventors: David Blum, Yanzhong Wu, Jean Schmid, Timothy Doyle, Jay Afragola
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Patent number: 7244736Abstract: The invention provides 6-chloro-5-{2,6-difluoro-4-[3-(methylamino)propoxy]phenyl}-2-pyrazin-2-yl-N-[(1S)-2,2,2-trifluoro-1-methylethyl]pyrimidin-4-amine hemifumarate which is a tubulin inhibitor useful in the treatment of cancer and processes of making hemifumarate compounds and compositioning of the present invention.Type: GrantFiled: June 12, 2006Date of Patent: July 17, 2007Assignee: WyethInventors: David Michael Blum, Yanzhong Wu, Jean Schmid, Timothy John Doyle, Jay Thomas Afragola
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Publication number: 20070129377Abstract: Processes are disclosed for preparing substituted aryl cycloalkanol derivatives, particularly chiral substituted aryl cycloalkanol derivatives of the general formula:Type: ApplicationFiled: December 4, 2006Publication date: June 7, 2007Applicant: WyethInventors: Alexander Gontcharov, Antonia Nikitenko, Jean Schmid, John Potoski
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Patent number: 7179911Abstract: Processes for using a compound of formula III: to make compounds of formulae I and II: and processes for making the compound of formula III, where R1-5 and J are as defined herein.Type: GrantFiled: June 7, 2005Date of Patent: February 20, 2007Assignee: WyethInventors: Ting-Zhong Wang, Lalitha Krishnan, Joseph Zeldis, Jeremy I. Levin, Jean Schmid, Mellard Jennings, Huan-Qiu Li, Zhixin Wen
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Publication number: 20060281760Abstract: The invention provides 6-chloro-5-{2,6-difluoro-4-[3-(methylamino)propoxy]phenyl}-2-pyrazin-2-yl-N-[(1S)-2,2,2-trifluoro-1-methylethyl]pyrimidin-4-amine hemifumarate which is a tubulin inhibitor useful in the treatment of cancer and processes of making said hemifumarate.Type: ApplicationFiled: June 12, 2006Publication date: December 14, 2006Applicant: WyethInventors: David Blum, Yanzhong Wu, Jean Schmid, Timothy Doyle, Jay Afragola
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Publication number: 20050272928Abstract: Processes for using a compound of formula III: to make compounds of formulae I and II: and processes for making the compound of formula III, where R1-5 and J are as defined herein.Type: ApplicationFiled: June 7, 2005Publication date: December 8, 2005Applicant: WyethInventors: Ting-Zhong Wang, Lalitha Krishnan, Joseph Zeldis, Jeremy Levin, Jean Schmid, Mellard Jennings, Huan-Qiu Li, Zhixin Wen
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Publication number: 20050124806Abstract: There is provided a process for the preparation of substituted amino alcohols HO—(CH2)n—NR1R2 from haloalcohols HO—(CH2)n—X, where X is Cl, Br or I, by reaction with an amine HNR1R2, in water as solvent at a temperature range of about 20° C. to about 90° C. optionally in the presence of a catalytic amount of an iodide source metal iodides. The haloalcohols are useful in the preparation of 6-[(substituted)phenyl]-triazolopyrimidine compounds which are useful in the treatment of cancer.Type: ApplicationFiled: December 8, 2004Publication date: June 9, 2005Applicant: WyethInventors: Yanzhong Wu, Arkadiy Rubezhov, Jean Schmid, Jay Afragola
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Publication number: 20050124635Abstract: The present invention provides a process for the preparation of 6-[(substituted)phenyl]-triazolopyrimidine dicarboxylic acid salt and as a hydrated salt having the structural formula (I) wherein: R1 is CF3 or C2F5; R2 is H or C1-C3 alkyl; n is an integer of 2, 3, or 4; X is Cl or Br; R3 and R4 are each independently H or C1-C3 alkyl; or R3 and R4 when optionally taken together with the nitrogen atom to which each is attached form a 4 to 6 membered saturated heterocyclic ring having 1-2 nitrogen atoms and 0-1 oxygen atoms or 0-1 sulfur atoms, and optionally substituted with R5; R5 is C1-C3 alkyl; wherein the dotted line is an optional bond.Type: ApplicationFiled: December 8, 2004Publication date: June 9, 2005Applicant: WyethInventors: Yanzhong Wu, Jean Schmid, Jay Afragola, David Blum, Semiramis Ayral-Kaloustian
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Patent number: 6011168Abstract: This invention relates to a process for the preparation of the formula I compound [2-((8,9)-dioxo-2,6-diazabicyclo[5.2.0]-non-1(7)-en-2-yl)ethyl]phosphonic acid, a NMDA antagonist useful as an anticonvulsant and neuroprotectant in situations involving excess release of excitatory amino acids. ##STR1## In the process of the present invention, 3-aminopropyl carbamic acid 1,1-dimethyl-ethyl ester is reacted with a dialkyl vinylphosphonate to obtain N-[3-(t-butyloxycarbonyl-amino)propyl ]-2-aminoethylphosphonic acid dialkyl ester (d) in 80% yield Reaction of (d) with a 3,4-dialkoxycyclobut-3-en-1,2-dione gives [3-[[2-(dialkoxyphosphoryl)ethyl ]-(2-alkoxy-3,4-dioxo-1,2-cyclobuten-1-yl)amino]propyl] carbamic acid 1,1-dimethylethyl ester (e) in 96% yield. Deprotection and cyclization of (e) in trifluoroacetic acid gives [2-((8,9)-dioxo-2,6-diazabicyclo[5.2.0]-non-1(7)-en-2-yl)ethyl]prosphonic acid dialkyl ester (c) in 58% yield.Type: GrantFiled: August 16, 1999Date of Patent: January 4, 2000Assignee: American Home Products CorporationInventors: Andre A. Asselin, William A. Kinney, Jean Schmid
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Patent number: 5990307Abstract: This invention relates to a process for the preparation of the formula I compound [2-((8,9)-dioxo-2,6-diazabicyclo[5.2.0]-non-1(7)-en-2-yl)ethyl]phosphonic acid, a NMDA antagonist useful as an anticonvulsant and neuroprotectant in situations involving excess release of excitatory amino acids. ##STR1## In the process of the present invention, 3-aminopropyl carbamic acid 1,1-dimethylethyl ester is reacted with a dialkyl vinylphosphonate to obtain N-[3-(t-butyloxycarbonyl-amino)propyl]-2-aminoethylphosphonic acid dialkyl ester (d) in 80% yield. Reaction of (d) with a 3,4-dialkoxycyclobut-3-en-1,2-dione gives [3-[[2-(dialkoxyphosphoryl)ethyl]-(2-alkoxy-3,4-dioxo-1,2-cyclobuten-1-yl) amino]propyl] carbamic acid 1,1-dimethylethyl ester (e) in 96% yield. Deprotection and cyclization of (e) in trifluoroacetic acid gives [2-((8,9)-dioxo-2,6-diazabicyclo[5.2.0]-non-1(7)-en-2-yl)ethyl]phosphonic acid dialkyl ester (c) in 58% yield.Type: GrantFiled: July 31, 1998Date of Patent: November 23, 1999Assignee: American Home Products CorporationInventors: Andre A. Asselin, William A. Kinney, Jean Schmid
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Patent number: 4925955Abstract: This invention relates to a process for resolving (.+-.)-cis-1-ethyl-1,3,4,9-tetrahydro-4-(phenylmethyl)pyrano[3,4-b]indole- 1-acetic acid (pemedolac) usinig brucine to obtain the corresponding (1S,4R)-eutomer. Said eutomer is useful as an analgesic.Type: GrantFiled: February 28, 1989Date of Patent: May 15, 1990Assignee: American Home Products CorporationInventors: Andre A. Asselin, Jean Schmid