Patents by Inventor Jean-Silvain Lacroix

Jean-Silvain Lacroix has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Treatment of substance P-related disorders
    Patent number: 6709651
    Abstract: The present invention is directed to methods of treating a wide variety of diseases, disorders and conditions characterized by excessive activity of substance P. The treatment involves administering peptidases that recognize and selectively cleave polypeptides at Xaa-Pro sequences.
    Type: Grant
    Filed: July 3, 2001
    Date of Patent: March 23, 2004
    Assignee: B.M.R.A. Corporation B.V.
    Inventors: Eric Grouzmann, Jean-Silvain Lacroix, Michel Monod
  • Template associated NPY Y2-receptor agonists
    Publication number: 20040009905
    Abstract: The present invention is directed to agonists of neuropeptide Y (NPY) or PYY that are formed by combining these peptides or a portion of these peptides with a template that promotes biologically active folds. Typically, templates consist of cyclized peptides containing one or more naphthyl ring structures. The agonists may be used in the treatment of diseases and conditions known to be responsive to NPY or PYY and, particularly in the treatment of asthma, rhinitis, and bronchitis.
    Type: Application
    Filed: June 18, 2003
    Publication date: January 15, 2004
    Applicant: B.M.R.A. Corporation B.V.
    Inventors: Manfred Mutter, Jean-Silvain Lacroix, Eric Grouzmann
  • Method of treating rhinitis or sinusitis
    Publication number: 20030165489
    Abstract: The present invention is directed to methods of treating mucosal inflammation associated with rhinitis or sinusitis by administering peptidases that recognize and cleave polypeptides at Xaa-Pro sequences. In addition, the invention encompasses therapeutic packages in which pharmaceutical compositions containing the peptidases are preloaded in a device suitable for intranasally delivering drug.
    Type: Application
    Filed: November 27, 2001
    Publication date: September 4, 2003
    Applicant: B.M.R.A. Corporation B.V.
    Inventors: Eric Grouzmann, Jean-Silvain Lacroix, Michel Monod
  • Treatment of substance P-related disorders
    Publication number: 20030007965
    Abstract: The present invention is directed to methods of treating a wide variety of diseases, disorders and conditions characterized by excessive activity of substance P. The treatment involves administering peptidases that recognize and selectively cleave polypeptides at Xaa-Pro sequences.
    Type: Application
    Filed: July 3, 2001
    Publication date: January 9, 2003
    Inventors: Eric Grouzmann, Jean-Silvain Lacroix, Michel Monod
  • Method of treating rhinitis or sinusitis by intranasally administering a peptidase
    Patent number: 6337069
    Abstract: The present invention is directed to methods of treating mucosal inflammation associated with rhinitis or sinusitis by administering peptidases that recognize and cleave polypeptides at Xaa-Pro sequences. In addition, the invention encompasses therapeutic packages in which pharmaceutical compositions containing the peptidases are preloaded in a device suitable for intranasally delivering drug.
    Type: Grant
    Filed: February 28, 2001
    Date of Patent: January 8, 2002
    Assignee: B.M.R.A. Corporation B.V.
    Inventors: Eric Grouzmann, Jean-Silvain Lacroix, Michel Monod
  • Template associated NPY Y2-receptor agonists
    Patent number: 6288029
    Abstract: The present invention is directed to agonists of neuropeptide Y (NPY) or PYY that are formed by combining these peptides or a portion of these peptides with a template that promotes biologically active folds. Typically, templates consist of cyclized peptides containing one or more naphthyl ring structures. The agonists may be used in the treatment of diseases and conditions known to be responsive to NPY or PYY and, particularly in the treatment of asthma, rhinitis, and bronchitis.
    Type: Grant
    Filed: January 14, 1999
    Date of Patent: September 11, 2001
    Inventors: Manfred Mutter, Jean-Silvain Lacroix, Eric Grouzmann
  • Template associated NPY Y2-receptor agonists
    Patent number: 6017879
    Abstract: The present invention is directed to agonists of neuropeptide Y (NPY) or PYY that are formed by combining these peptides or a portion of these peptides with a template that promotes biologically active folds. Typically, templates consist of cyclized peptides containing one or more naphthyl ring structures. The agonists may be used in the treatment of diseases and conditions known to be responsive to NPY or PYY and, particularly in the treatment of asthma, rhinitis, and bronchitis.
    Type: Grant
    Filed: April 3, 1998
    Date of Patent: January 25, 2000
    Assignee: B.M.R.A. Corporation B.V.
    Inventors: Manfred Mutter, Jean-Silvain Lacroix, Eric Grouzmann