Abstract: The present invention generally relates to a personalized cancer vaccine comprising a recombinant poxvirus encoding one or more neopeptide(s) or a composition comprising such a recombinant poxvirus and a pharmaceutically acceptable vehicle as well as the use of the personalized cancer vaccine for treating a cancerous subject in need thereof. A specific embodiment is directed to a method of providing such a vaccine or composition comprising an identification step comprising a) extracting the DNA from a tumor sample and a non-tumor sample, b) selecting target regions, c) sequencing the target regions from the extracted DNAs and d) identifying one or more tumor-specific mutation(s) by comparing the DNA sequences obtained from the tumor and non-tumor samples. Embodiments also include a method of treating cancer or preventing its relapse comprising administration of such a personalized cancer vaccine. The invention is of very special interest in the field of personalized immunotherapy.

Abstract: A method and means for masking at least a part of a surface to be treated wherein an element that is resistant to surface treatment operations is removably applied to said part of said surface and is removed after finishing said treatment. As element a compressible cushion is applied on at least a portion of an irregularity in said surface wherein said cushion is adaptable to the irregularity on which it is applied.

Abstract: Method for masking at least part of a surface to be treated wherein an elongated, compressible, windowless, masking cushion that is resistant to the treatment is removably applied by an adhesive to the at least part of the surface to be treated. When the compressible cushion is used to mask an irregularity in the surface to be treated, such as an opening in the body of a vehicle, the cushion is adaptable to the irregularity.