Patents by Inventor Jeff Bickmeier

Jeff Bickmeier has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9090898
    Abstract: Recombinant hosts for producing polyhydroxyalkanoates and methods of producing polyhydroxyalkanoates from renewable carbon substrates are provided. Certain recombinant hosts that produce 5 carbon chemicals such as 5-aminopentanoate (5AP), 5-hydroxyvalerate (5HV), glutarate, and 1,5 pentanediol (PDO) are also provided. One embodiment provides a recombinant host expressing a gene encoding a heterologous enzyme selected from the group consisting of a polyhydroxyalkanoate synthase and a 5-hydroxyvalerate-CoA (5HV-CoA) transferase, wherein the host produces a polymer containing 5-hydroxyvalerate. Preferably, the host expresses both a polyhydroxyalkanoate synthase and a 5HV-CoA transferase. The host can be prokaryotic or eukaryotic. A preferred prokaryotic host is E. coli. The polymers produced by the recombinant hosts can be homopolymers or copolymers of 5-hydroxyvalerate. A preferred copolymer is poly(3-hydroxybutyrate-co-5-hydroxyvalerate).
    Type: Grant
    Filed: December 14, 2009
    Date of Patent: July 28, 2015
    Assignee: Metabolix, Inc.
    Inventors: William R. Farmer, Jeff Bickmeier, Chenfeng Lu, Dong-Eun Chang, Frank Skraly, Thomas Martin Ramseier
  • Publication number: 20150159184
    Abstract: Methods and genetically engineered hosts for the production of poly-4-hydroxybutrate and 4-carbon products are described herein.
    Type: Application
    Filed: March 4, 2013
    Publication date: June 11, 2015
    Inventors: Thomas M. Ramseier, Christopher W.J. McChalicher, William R. Farmer, Zhigang Zhang, Dong-Eun Chang, Jeff Bickmeier, Julie Beaulieu, Catherine Morse
  • Publication number: 20100168481
    Abstract: Recombinant hosts for producing polyhydroxyalkanoates and methods of producing polyhydroxyalkanoates from renewable carbon substrates are provided. Certain recombinant hosts that produce 5 carbon chemicals such as 5-aminopentanoate (5AP), 5-hydroxyvalerate (5HV), glutarate, and 1,5 pentanediol (PDO) are also provided. One embodiment provides a recombinant host expressing a gene encoding a heterologous enzyme selected from the group consisting of a polyhydroxyalkanoate synthase and a 5-hydroxyvalerate-CoA (5HV-CoA) transferase, wherein the host produces a polymer containing 5-hydroxyvalerate. Preferably, the host expresses both a polyhydroxyalkanoate synthase and a 5HV-CoA transferase. The host can be prokaryotic or eukaryotic. A preferred prokaryotic host is E. coli. The polymers produced by the recombinant hosts can be homopolymers or copolymers of 5-hydroxyvalerate. A preferred copolymer is poly(3-hydroxybutyrate-co-5-hydroxyvalerate).
    Type: Application
    Filed: December 14, 2009
    Publication date: July 1, 2010
    Inventors: William R. Farmer, Jeff Bickmeier, Chenfeng Lu, Dong-Eun Chang, Frank Skraly, Thomas Martin Ramseier