Patents by Inventor Jeff J. Hutchison

Jeff J. Hutchison has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Preparation of Amides of Retinoic Acid Via Mixed Anhydride and Mixed Carbonate Intermediates
    Publication number: 20080221349
    Abstract: Processes for preparing amides of retinoic acid are disclosed. Intermediates useful in the preparation of amides of retinoic acid are also disclosed. In one version of the invention, fenretinide is produced via activation of retinoic acid (tretinoin) via its corresponding mixed anhydride or mixed carbonate followed by reaction of the activated intermediate with 4-aminophenol. Other amides of retinoic acid and isomers of retinoic acid, such as the 9-cis-form or 13-cis-form can also be made by this invention.
    Type: Application
    Filed: January 2, 2008
    Publication date: September 11, 2008
    Inventors: John E. Cabaj, Jeff J. Hutchison, James R. Zeller
  • Preparation of amides of retinoic acid via mixed anhydride and mixed carbonate intermediates
    Patent number: 7321064
    Abstract: Processes for preparing amides of retinoic acid are disclosed. Intermediates useful in the preparation of amides of retinoic acid are also disclosed. In one version of the invention, fenretinide is produced via activation of retinoic acid (tretinoin) via its corresponding mixed anhydride or mixed carbonate followed by reaction of the activated intermediate with 4-aminophenol. Other amides of retinoic acid and isomers of retinoic acid, such as the 9-cis-form or 13-cis-form can also be made by this invention.
    Type: Grant
    Filed: March 8, 2007
    Date of Patent: January 22, 2008
    Assignee: Cedarburg Pharmaceuticals, Inc.
    Inventors: John E. Cabaj, Jeff J. Hutchison