Patents by Inventor Jeffery R. X. Auld

Jeffery R. X. Auld has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10258983
    Abstract: An apparatus comprises a biosensor disk structure including a first substrate with a first inner surface, a second substrate with a second inner surface facing oppositely toward the first inner surface, and fluidic channels reaching between the first and second inner surfaces; wherein the first inner surface has binding sites and non-binding sites adjoining the binding sites, the first substrate is transparent at the non-binding sites, and the non-binding sites have discrete polygonal configurations of equal size and shape; and the second inner surface has non-reflective areas and reflective areas bounded by the non-reflective areas, and the reflective areas have discrete polygonal configurations sized and shaped equally with the non-binding sites such that the reflective areas are located coextensively opposite the non-binding sites.
    Type: Grant
    Filed: August 7, 2018
    Date of Patent: April 16, 2019
    Assignee: ADVANCED TECHNOLOGY APPLICATIONS, LLC
    Inventors: Jeffery R. X. Auld, James E. Smith
  • Publication number: 20190083981
    Abstract: An apparatus comprises a biosensor disk structure including a first substrate with a first inner surface, a second substrate with a second inner surface facing oppositely toward the first inner surface, and fluidic channels reaching between the first and second inner surfaces; wherein the first inner surface has binding sites and non-binding sites adjoining the binding sites, the first substrate is transparent at the non-binding sites, and the non-binding sites have discrete polygonal configurations of equal size and shape; and the second inner surface has non-reflective areas and reflective areas bounded by the non-reflective areas, and the reflective areas have discrete polygonal configurations sized and shaped equally with the non-binding sites such that the reflective areas are located coextensively opposite the non-binding sites.
    Type: Application
    Filed: August 7, 2018
    Publication date: March 21, 2019
    Applicant: Advanced Technology Applications, LLC
    Inventors: Jeffery R.X. Auld, James E. Smith
  • Publication number: 20190041387
    Abstract: The presently disclosed subject matter relates to a biodetection system centered on the development and optimization of a logistically simple assay for detecting, identifying, and/or quantifying microbial pathogens using an unmodified substrate. Specifically, the disclosed system quantitatively measures target analytes (e.g., bacteria) isolated over a digitally-encoded substrate. Isolated microbes are positioned in specific locations and geometries on the substrate data surface, resulting in a discernible interruption and/or change to data being read from the substrate. The change can be exploited to indicate positive detection and detection counts for one or more specific microbes.
    Type: Application
    Filed: July 31, 2018
    Publication date: February 7, 2019
    Inventor: Jeffery R.X. Auld
  • Patent number: 10183290
    Abstract: A method may include steps of binding an analyte to a ligand, exposing the analyte to light of differing wavelengths, and observing a difference in spectral response of the analyte at the differing wavelengths. Further steps may include comparing the observed difference with a known difference in spectral response of a reference substance at the differing wavelengths, and determining whether the observed difference meets a predetermined threshold of identity with the known difference. The method may be performed with reference to a surface having a reflective area with a known size a non-reflective area adjacent to the reflective area. The method may thus include the steps of providing a ligand in alignment with the non-reflective area of the surface, and binding an analyte to the ligand in a position reaching across the reflective area.
    Type: Grant
    Filed: April 16, 2015
    Date of Patent: January 22, 2019
    Assignee: ADVANCED TECHNOLOGY APPLICATIONS, LLC
    Inventors: Jeffery R. X. Auld, James E. Smith
  • Patent number: 10040066
    Abstract: A biosensor disk includes a detection substrate with an upper side surface, a reflection substrate with a lower side surface facing oppositely toward the upper side surface, and fluidic channels reaching between the opposed side surfaces. The upper side surface has binding sites, and has non-binding sites adjoining the binding sites. The detection substrate is transparent at the non-binding sites. The lower side surface has non-reflective areas, and has reflective areas adjoining the non-reflective areas. The reflective areas are located opposite the non-binding sites and have discrete polygonal configurations of equal size and shape.
    Type: Grant
    Filed: May 27, 2015
    Date of Patent: August 7, 2018
    Assignee: Advanced Technology Applications, LLC
    Inventor: Jeffery R. X. Auld
  • Publication number: 20160305876
    Abstract: A method may include steps of binding an analyte to a ligand, exposing the analyte to light of differing wavelengths, and observing a difference in spectral response of the analyte at the differing wavelengths. Further steps may include comparing the observed difference with a known difference in spectral response of a reference substance at the differing wavelengths, and determining whether the observed difference meets a predetermined threshold of identity with the known difference. The method may be performed with reference to a surface having a reflective area with a known size a non-reflective area adjacent to the reflective area. The method may thus include the steps of providing a ligand in alignment with the non-reflective area of the surface, and binding an analyte to the ligand in a position reaching across the reflective area.
    Type: Application
    Filed: April 16, 2015
    Publication date: October 20, 2016
    Applicant: ADVANCED TECHNOLOGY APPLICATIONS, LLC
    Inventors: Jeffery R.X. Auld, James E. Smith
  • Publication number: 20160303560
    Abstract: A biosensor disk includes a detection substrate with an upper side surface, a reflection substrate with a lower side surface facing oppositely toward the upper side surface, and fluidic channels reaching between the opposed side surfaces. The upper side surface has binding sites, and has non-binding sites adjoining the binding sites. The detection substrate is transparent at the non-binding sites. The lower side surface has non-reflective areas, and has reflective areas adjoining the non-reflective areas. The reflective areas are located opposite the non-binding sites and have discrete polygonal configurations of equal size and shape.
    Type: Application
    Filed: May 27, 2015
    Publication date: October 20, 2016
    Applicant: Advanced Technology Applications, LLC
    Inventor: Jeffery R.X. Auld
  • Patent number: 8735846
    Abstract: A system, method, device, and process for making and using an electromagnetic-sensitive biosensor on a biosensor disk to identify and classify an analyte in a sample. The biosensor of the biosensor disk is exposed to a sample containing analytes and a desired analyte adheres to the biosensor. The biosensor is exposed to microspheres that adhere to the analyte. The microspheres cause a detectable change to electromagnetic radiation incident upon the biosensor disk The biosensor disk is rotated during operation and an electromagnetic emitter directs an electromagnetic radiation beam at the biosensor disk. The returned electromagnetic radiation from the biosensor disk is received by a sensor and converted into a signal to indicate the presence of the desired analyte in the sample.
    Type: Grant
    Filed: October 11, 2010
    Date of Patent: May 27, 2014
    Assignee: Advanced Technology Applications, LLC
    Inventor: Jeffery R. X. Auld