Patents by Inventor Jeffrey Clayton Baker

Jeffrey Clayton Baker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cryogranulation of activated protein C
    Patent number: 6815533
    Abstract: The present invention is directed at a method of processing an aqueous solution of protein C into a state suitable for storage, handling, and recovery. The present invention provides aqueous activated protein C solutions and an improved method of processing such solutions into cryogranules.
    Type: Grant
    Filed: January 22, 2001
    Date of Patent: November 9, 2004
    Assignee: Eli Lilly and Company
    Inventors: Jeffrey Clayton Baker, Nancy Delores Jones
  • Activated protein C formulations
    Patent number: 6436397
    Abstract: The present invention is broadly directed to a method for reducing autodegradation of activated protein C during processing and purification. The present invention provides aqueous activated protein C solutions and an improved method of processing of such solutions, comprising conducting such processing at an ionic strength of greater than 150 mM and at a pH of about 5.5 to less than 6.3.
    Type: Grant
    Filed: September 21, 2000
    Date of Patent: August 20, 2002
    Assignee: Eli Lilly and Company
    Inventors: Jeffrey Clayton Baker, Andrew David Carlson, Lihua Huang, Theodore Arsay Sheliga
  • Methods for processing activated protein C
    Patent number: 6162629
    Abstract: The present invention is broadly directed to a method for reducing autodegradation of activated protein C during processing and purification. The present invention provides aqueous activated protein C solutions and an improved method of processing of such solutions, comprising conducting such processing at an ionic strength of greater than 150 mM and at a pH of about 5.5 to less than 6.3.
    Type: Grant
    Filed: April 24, 1998
    Date of Patent: December 19, 2000
    Assignee: Eli Lilly And Company
    Inventors: Jeffrey Clayton Baker, Andrew David Carlson, Lihua Huang, Theodore Arsay Sheliga
  • Preparation of an acylated protein powder
    Patent number: 5700904
    Abstract: A method for recovering an acylated protein as a powder, especially in cases where said acylated protein is one that resists isolation by isoelectric precipitation from aqueous solutions of the protein, said method comprising in combination adjusting said aqueous solution to near the isoelectric pH of the protein and providing a suitable alcohol concentration to cause precipitation of the protein in the form of filterable particles at said pH.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: December 23, 1997
    Assignee: Eli Lilly and Company
    Inventors: Jeffrey Clayton Baker, Brian A. Moser, Warren E. Shrader