Abstract: An embodiment relates to a selective agonist of neuronal nicotinic acetylcholine receptor ?7 subtype, a pharmaceutically suitable salt, prodrug, or a metabolite thereof, for the prevention and treatment of diseases and conditions that are mediated by nicotinic acetylcholine receptors, and methods of use thereof. Another embodiment is a method of administering a pharmaceutically effective amount of a selective agonist of neuronal nicotinic acetylcholine receptor ?7 subtype, a pharmaceutically suitable salt, prodrug, or a metabolite thereof, to a mammal in need thereof.

Abstract: An embodiment relates to a selective agonist of neuronal nicotinic acetylcholine receptor ?7 subtype, a pharmaceutically suitable salt, prodrug, or a metabolite thereof, for the prevention and treatment of diseases and conditions that are mediated by nicotinic acetylcholine receptors, and methods of use thereof. Another embodiment is a method of administering a pharmaceutically effective amount of a selective agonist of neuronal nicotinic acetylcholine receptor ?7 subtype, or a pharmaceutically suitable salt, prodrug, or a metabolite thereof, to a mammal in need thereof.

Abstract: A theft prevention device is provided for an anhydrous ammonia tank having a feed pipe with an open end. The theft prevention device includes a plug body which is inserted into the open end of the feed pipe. The plug body includes a flexible member which can be expanded by a keyed lock actuator so as to engage the interior of the feed pipe and prevent removal of the plug member. Locking and unlocking of the plug member to the interior of the feed pipe can be accomplished only by use of a key having a predetermined configuration which fits the keyed lock actuator.

Abstract: A clip applicator adapted to apply and remove C-shaped scalp clips from a surgical incision site, wherein the clip applicator includes a body, a trigger and a lever mounted on the body and mutually operable between respective first and second positions relative to the body. The lever includes a clip-engaging portion disposed at a distal end thereof and a trigger-engaging portion disposed at a proximal end thereof. The lever is movable from the lever first position to the lever second position in response to the trigger moving from a trigger first position to a trigger second position. The clip applicator further includes a magazine that is releasably fastened to the body. The magazine is adapted to store a plurality of clips, and to serially dispense the clips from the magazine.