Abstract: An apparatus and method for controlling a water characteristic of a body of water by controlling the cyclic release of a water characteristic material into the body of water with or without the system being responsive to a level of the water characteristic in the body of water.

Abstract: The invention provides apoptosis signaling kinase related kinase (ASKRK) nucleic acid and polypeptide sequences and methods of using such sequences to identify modulators of ASKRK. Such modulators can be used for the treatment of diabetes or for delaying the onset of diabetes. The invention also provides methods of diagnosing diabetes or pre-diabetes and methods of making a prognosis based on the detection of ASKRK nucleic acids and proteins.

Abstract: A liquid treatment method and system with the liquid treatment system having a container for holding a liquid treatment material therein with the liquid treatment device effectively positionable in various transitional regions in the liquid system to provide for an enhanced dispersant rate in response to increased activity in the body of water.

Abstract: The present invention provides a pancreatic islet transcription factor and methods of treating and diagnosing diabetes.

Abstract: The optimization of product prices using business segmentation is provided. The business is segmented into a plurality of selected segments, each including a subset of products. Segmenting utilizes fixed dimensions and variable dimensions. Pricing power and pricing risk is computed for each segment. Pricing power is an ability to alter pricing of the products within the segment. Pricing risk is a risk factor associated with an alteration to pricing of the products within the segment. Pricing objectives are generated for each segment by comparing the pricing power to the pricing risk of the segment. Prices are optimized using the pricing objectives. Prices are set based on optimized prices. Price lists and policies may be managed, including negotiating of prices based on optimized prices. Additionally, the entire system may be linked to an enterprise resource system.

Abstract: The invention provides apoptosis signaling kinase related kinase (ASKRK) nucleic acid and polypeptide sequences and methods of using such sequences to identify modulators of ASKRK. Such modulators can be used for the treatment of diabetes or for delaying the onset of diabetes. The invention also provides methods of diagnosing diabetes or pre-diabetes and methods of making a prognosis based on the detection of ASKRK nucleic acids and proteins.

Abstract: The invention relates to methods and reagents for diagnosing and treating diabetes.

Abstract: The invention relates to methods of determining islet cell activity by detecting the level of Archipelin or a fragment thereof and comparing the level to a baseline level or range associated with a known islet cell activity. Such methods are useful in diagnosing and studying the development of diabetes.

Abstract: The invention provides apoptosis signaling kinase related kinase (ASKRK) nucleic acid and polypeptide sequences and methods of using such sequences to identify modulators of ASKRK. Such modulators can be used for the treatment of diabetes or for delaying the onset of diabetes. The invention also provides methods of diagnosing diabetes or pre-diabetes and methods of making a prognosis based on the detection of ASKRK nucleic acids and proteins.

Abstract: Expression of beta-TRP is enriched in islet cells. Introduction of expression cassettes encoding beta-TRP into diabetic islet cells improved glucose-stimulated insulin production.

Abstract: The present invention provides polynucleotides encoding potassium channels as well as methods of using the potassium channels to treat and diagnose diabetes and a predisposition for diabetes.

Abstract: A water treatment device, method and system with the water treatment device having a container for holding a water treatment material therein with the water treatment device including a shroud extending in a direction generally normal to a flow of debris laden water with the shroud inhibiting direct flow of debris into a water inlet in the water treatment device by directing water and debris over the shroud and around the water treatment device while a portion of the water can be directed laterally into the water treatment material within the water treatment device to thereby purify the water that flows over the water treatment materials with the water treatment device including multiple spaced and positioned water inlets so that the likelihood of the water inlet being completely obstructed is remote.

Abstract: Expression of beta-TRP is enriched in islet cells. Introduction of expression cassettes encoding beta-TRP into diabetic islet cells improved glucose-stimulated insulin production.

Abstract: A mobile device for a vehicle is disclosed, which uses scripts provided from a server. The scripts can include indications that indicate the appropriateness of input data. Additionally, the scripts can include conditional actions that only occur when certain input data values are recorded.

Abstract: A water treatment device, method and system with the water treatment device having a container for holding a water treatment material therein with the water treatment device including a shroud extending in a direction generally normal to a flow of debris laden water with the shroud inhibiting direct flow of debris into a water inlet in the water treatment device by directing water and debris over the shroud and around the water treatment device while a portion of the water can be directed laterally into the water treatment material within the water treatment device to thereby purify the water that flows over the water treatment materials with the water treatment device including multiple spaced and positioned water inlets so that the likelihood of the water inlet being completely obstructed is remote.

Abstract: The present invention provides polynucleotides encoding potassium channels as well as methods of using the potassium channels to treat and diagnose diabetes and a predisposition for diabetes.

Abstract: A water treatment device, method and system with the water treatment device having a container for holding a water treatment material therein with the water treatment device including a shroud extending in a direction generally normal to a flow of debris laden water with the shroud inhibiting direct flow of debris into a water inlet in the water treatment device by directing water and debris over the shroud and around the water treatment device while a portion of the water can be directed laterally into the water treatment material within the water treatment device to thereby purify the water that flows over the water treatment materials with the water treatment device including multiple spaced and positioned water inlets so that the likelihood of the water inlet being completely obstructed is remote.

Abstract: The invention provides isolated nucleic acid and amino acid sequences of human and murine islet cell G-protein coupled receptors, antibodies to such receptors, methods of detecting such nucleic acids and receptors, methods of screening for modulators of islet cell G-protein coupled receptors and methods of treating mammals with modulators of islet cell G-protein coupled receptor activity.

Abstract: The invention relates to methods and reagents for diagnosing and treating diabetes.