Patents by Inventor Jeffrey E. Miripol

Jeffrey E. Miripol has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5888328
    Abstract: A kit for testing the integrity of sterile tubing welds made by a sterile tubing welding machine employing welding wafers includes a plurality of tubing samples, and a container having a series of receptacles for holding the tubing samples and the wafers used in the sterile tubing welding machine. A set of instructions is provided for making the sterile tubing welds with the tubing samples in the container, and a data sheet is included for recording particulars of the kit and reporting a weld analysis.
    Type: Grant
    Filed: June 26, 1997
    Date of Patent: March 30, 1999
    Assignee: Terumo Medical Corporation
    Inventors: Jeffrey E. Miripol, Joseph H. Meier, Jr., Randall L. Graybeal, Benjamin A. Hill
  • Patent number: 4952812
    Abstract: A thin film or layer of white blood cells, such as the contaminating white cells in a platelet concentrate, is irradiated with ultraviolet radiation predominately of a wavelength of 280 to 320 nanometers, and preferably at an intensity of 4 to 20 milliwatts per square cm. to provide a total energy exposure of typically 800 to 20,000 millijoules per square cm. of ultraviolet radiation. The white blood cells so produced substantially lose their capability to set off an immune reaction in an alloimmunized patient. The white blood cells may preferably be placed into such film in a flat, flexible bag made of poly(ethylene-vinyl acetate) plastic, with the flat, flexible bag being stretched in a direction normal to the path of ultraviolet radiation. Novel irradiating devices are also disclosed.
    Type: Grant
    Filed: May 2, 1989
    Date of Patent: August 28, 1990
    Assignee: Baxter International Inc.
    Inventors: Jeffrey E. Miripol, Arnold Bilstad, John Foley, Dean Glash, William R. Bratten
  • Patent number: 4866282
    Abstract: A thin film of white blood cells is irradiated with ultraviolet radiation predominately of a wavelength of 280 to 320 nanometers, and preferably at an intensity of 4 to 15 milliwatts per square cm. At such a radiation intensity it is not necessary to agitate the thin film of white blood cells to accomplish the purposes of this invention. The white blood cells so processed substantially lose their capability to set off an immune reaction in an alloimmunized patient. The white blood cells may preferably be placed into such film in a flat, flexible bag made of poly(ethylene-vinyl acetate) plastic, with the flat, flexible bag being stretched in a direction normal to the path of ultraviolet radiation.
    Type: Grant
    Filed: February 17, 1988
    Date of Patent: September 12, 1989
    Assignee: Baxter International Inc.
    Inventors: Jeffrey E. Miripol, Arnold Bilstad, John Foley, Dean Glash
  • Patent number: 4846005
    Abstract: A fluid delivery system has a container with an integrally attached sample cell. A selected fluid can be accumulated in the container. The sample cell can be filled with part of the fluid in the container and then isolated from the container by heat or dielectric sealing. The fluid in the sample cell can be brought into contact with selected test reagents. The test reagents can provide a visual indicia of the presence of selected characteristics in the fluid.
    Type: Grant
    Filed: August 5, 1987
    Date of Patent: July 11, 1989
    Assignee: Baxter International Inc.
    Inventors: David V. Bacehowski, Arnold C. Bilstad, Patrick N. Huehls, Stephen B. Kaufman, Jeffrey E. Miripol
  • Patent number: 4726949
    Abstract: A thin film of white blood cells is irradiated with ultraviolet radiation predominately of a wavelength of 280 to 320 nanometers, and preferably at an intensity of 4 to 15 milliwatts per square cm. At such a radiation intensity it is not necessary to agitate the thin film of white blood cells to accomplish the purposes of this invention. The white blood cells so processed substantially lose their capability to set off an immune reaction in an alloimmunized patient. The white blood cells may preferably be placed into such film in a flat, flexible bag made of poly(ethylene-vinyl acetate) plastic, with the flat, flexible bag being stretched in a direction normal to the path of ultraviolet radiation.
    Type: Grant
    Filed: August 26, 1986
    Date of Patent: February 23, 1988
    Assignee: Baxter Travenol Laboratories, Inc.
    Inventors: Jeffrey E. Miripol, Arnold Bilstad, John Foley, Dean Glash
  • Patent number: 4704352
    Abstract: A solution for blood cell storage having sugar-containing blood cell nutrients therein and additionally containing a magnesium or calcium L-ascorbate-2-phosphate salt is taught. The magnesium and calcium L-ascorbate-2-phosphate salts remain stable below pH 7 and thus permit sterilization of the solution at a pH at which degradation of both the L-ascorbate-2-phosphate salt and the nutrient sugar present in the solution is substantially avoided.
    Type: Grant
    Filed: June 25, 1985
    Date of Patent: November 3, 1987
    Assignee: Baxter Travenol Laboratories, Inc.
    Inventors: Jeffrey E. Miripol, Andrew Heaton, Richard L. Kandler
  • Patent number: 4286597
    Abstract: Blood-compatible, chlorine-free polymers such as a flexible, non-toxic, sterilizable polyester plastic formulation may contain from 5 to 70 percent by weight of a blood-extractable plasticizer such as di-2-ethylhexyladipate, to cause blood which is stored in contact with the polymer to exhibit a surprisingly low hemolysis rate when compared with corresponding polymers which are free of the plasticizer. Accordingly, blood bags, tubing and other medical blood-contacting devices may be advantageously made from these polymers.
    Type: Grant
    Filed: April 21, 1980
    Date of Patent: September 1, 1981
    Assignee: Baxter Travenol Laboratories, Inc.
    Inventors: Henry M. Gajewski, Gerald A. Grode, Paul E. Measells, Jeffrey E. Miripol
  • Patent number: 4267269
    Abstract: An aqueous red cell storage solution for packed cells which permits removal of essentially all plasma from a unit of blood, followed by reconstitution of the packed cells of the unit in preferably about 80 to 150 ml. of solution for improved cell viability on long term storage. The red cell storage solution contains adenine, glucose or fructose, sodium chloride, and mannitol.
    Type: Grant
    Filed: February 5, 1980
    Date of Patent: May 12, 1981
    Assignee: Baxter Travenol Laboratories, Inc.
    Inventors: Gerald A. Grode, Jeffrey E. Miripol