Patents by Inventor Jeffrey E. Pessin

Jeffrey E. Pessin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20140051661
    Abstract: The present invention provides resveratrol-based boron-containing analog! methods of use thereof in treatment of dyslipidemias and cancer.
    Type: Application
    Filed: February 15, 2012
    Publication date: February 20, 2014
    Applicants: The Texas A&M University System, Albert Einstein College of Medicine of Yeshiva University
    Inventors: Bhaskar C. Das, Fajun Yang, Xiaoping Zhao, Jeffrey E. Pessin, Haihong Zong, Jun-Yuan Ji
  • Publication number: 20130039857
    Abstract: The present invention provides methods for determining if an agent (i) treats or prevents cancer, (ii) treats or prevents obesity, and/or (iii) increases insulin sensitivity, comprising contacting Fyn and/or LKB1 with the agent and determining if the agent inhibits Fyn kinase activity or inhibits the interaction between Fyn and LKB1, wherein inhibition of Fyn kinase activity or inhibition of the interaction between Fyn and LKB1 by the agent indicates that the agent (i) treats or prevents cancer, (ii) treats or prevents obesity, and/or (iii) increases insulin sensitivity. The present invention also provides methods for treating cancer, treating obesity, or increasing insulin sensitivity in a subject, comprising administering to the subject a therapeutically effective amount of an agent that inhibits Fyn kinase or that inhibits the interaction between Fyn and LKB1.
    Type: Application
    Filed: March 9, 2011
    Publication date: February 14, 2013
    Inventors: Jeffrey E. Pessin, Claire C. Bastie, Eijiro Yamada