Patents by Inventor Jeffrey H. Rothman

Jeffrey H. Rothman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and compositions for treating cancer using peptide nucleic acid-based agents
    Patent number: 11518996
    Abstract: The present invention provides compositions and methods for treating cancer with peptide nucleic acid agents. In some embodiments, the present invention provides methods and compositions relating to peptide nucleic acid agents that target oncogenes. For example, the present invention provides compositions, including pharmaceutical compositions, comprising agents specific for BRAF V600E inhibition, or fragments or characteristic portions thereof. The present invention further provides various therapeutic and/or diagnostic methods of using BRAF V600E specific peptide nucleic acid agents and/or compositions.
    Type: Grant
    Filed: August 7, 2020
    Date of Patent: December 6, 2022
    Assignee: MEMORIAL SLOAN-KETTERING CANCER CENTER
    Inventors: Jeffrey H. Rothman, Gary K. Schwartz
  • Methods and compositions for treating cancer using peptide nucleic acid-based agents
    Patent number: 10858655
    Abstract: The present invention provides compositions and methods for treating cancer with peptide nucleic acid agents. In some embodiments, the present invention provides methods and compositions relating to peptide nucleic acid agents that target oncogenes. For example, the present invention provides compositions, including pharmaceutical compositions, comprising agents specific for BRAF V600E inhibition, or fragments or characteristic portions thereof. The present invention further provides various therapeutic and/or diagnostic methods of using BRAF V600E specific peptide nucleic acid agents and/or compositions.
    Type: Grant
    Filed: October 29, 2018
    Date of Patent: December 8, 2020
    Assignee: MEMORIAL SLOAN-KETTERING CANCER CENTER
    Inventors: Jeffrey H. Rothman, Gary K. Schwartz
  • METHODS AND COMPOSITIONS FOR TREATING CANCER USING PEPTIDE NUCLEIC ACID-BASED AGENTS
    Publication number: 20190284561
    Abstract: The present invention provides compositions and methods for treating cancer with peptide nucleic acid agents. In some embodiments, the present invention provides methods and compositions relating to peptide nucleic acid agents that target oncogenes. For example, the present invention provides compositions, including pharmaceutical compositions, comprising agents specific for BRAF V600E inhibition, or fragments or characteristic portions thereof. The present invention further provides various therapeutic and/or diagnostic methods of using BRAF V600E specific peptide nucleic acid agents and/or compositions.
    Type: Application
    Filed: October 29, 2018
    Publication date: September 19, 2019
    Inventors: Jeffrey H. Rothman, Gary K. Schwartz
  • Methods and compositions for treating cancer using peptide nucleic acid-based agents
    Patent number: 10113169
    Abstract: The present invention provides compositions and methods for treating cancer with peptide nucleic acid agents. In some embodiments, the present invention provides methods and compositions relating to peptide nucleic acid agents that target oncogenes. For example, the present invention provides compositions, including pharmaceutical compositions, comprising agents specific for BRAF V600E inhibition, or fragments or characteristic portions thereof. The present invention further provides various therapeutic and/or diagnostic methods of using BRAF V600E specific peptide nucleic acid agents and/or compositions.
    Type: Grant
    Filed: December 17, 2014
    Date of Patent: October 30, 2018
    Assignee: Memorial Sloan-Kettering Cancer Center
    Inventors: Jeffrey H. Rothman, Gary K. Schwartz
  • Cosmetic Contact Lenses Having a Sparkle Effect
    Publication number: 20090190091
    Abstract: The invention provides sparkle additives useful in producing cosmetic lenses, and lenses produced using the sparkle additives that produce a sparkle-effect when the lens is viewed on-eye. The sparkle effect is produced while, at the same time, maintaining the natural appearance of the eye.
    Type: Application
    Filed: December 18, 2008
    Publication date: July 30, 2009
    Inventors: Dawn D. Wright, Diana Zanini, Kanda Kumar Balasubramanian, Terry L. Spaulding, Douglas G. Evans, Jeffrey H. Rothman, Karin D. McCarthy