Abstract: A cell genetically modified to comprise at least one mechanism for providing a local immunosuppression at a transplant site when transplanted in an allogeneic host is, and methods for making and using the same is provided. The cell comprises a set of transgenes, each transgene encoding a gene product that is cytoplasmic, membrane bound, or local acting, and whose function is one or more of: to mitigate antigen presenting cell activation and function; to mitigate graft attacking leukocyte activity or cytolytic function; to mitigate macrophage cytolytic function and phagocytosis of allograft cells; to induce apoptosis in graft attacking leukocytes; to mitigate local inflammatory proteins; and to protect against leukocyte-mediated apoptosis.

Abstract: A device may transmit questionnaires to a set of client devices, wherein the questionnaires include a set of questions that relate to an internal entity experience attribute and/or an external entity experience attribute. The device may receive a set of questionnaire responses and correlate the set of questionnaire responses with contextual data relating to an entity. The device may process, using a machine learning model trained based on data relating to one or more other entities, the set of questionnaire responses and the contextual data to identify a set of features and a set of feature ranks. The device may select a subset of features based on the set of feature ranks and a set of influence thresholds. The device may generate a set of recommendations associated with the subset of features and communicate with one or more other devices to implement the set of recommendations.

Abstract: Featured are cells and methods of use thereof for modulating an antigen-specific immune response in a subject. The cells comprise a set of transgenes comprising two or more of PD-L1, HLA-G or H2-M3, Cd47, Cd200, FASG or FasL, Ccl21 or Ccl21b, MfgeS and Serpin B9 or Spi6, that shield the cells from immune surveillance (ie. “cloaking genes”). The cells can be used to induce immune tolerance to an antigen (e.g., a donor alloantigen or a self-antigen), or to induce an immune response to (e.g., induce the production of antibodies directed against) a non-self antigen.

Abstract: Technologies for decentralized fleet analytics are disclosed. In at least one embodiment, a local cloud service at a plant site builds a first machine learning model of one or more first streams of data associated with the plant site. The local cloud service sends the first machine learning model to a cloud service connected to the plant site and other plant sites. The local cloud service receives a second machine learning model from the cloud service. The second machine learning model is trained as a function of the first machine learning model and one or more machine learning models built by the other plant sites. The local cloud service updates the first machine learning model based on the second machine learning model.

Abstract: A cell genetically modified to comprise at least one mechanism for providing a local immunosuppression at a transplant site when transplanted in an allogeneic host, and methods for making and using the same are provided. The cell comprises a set of transgenes, each transgene encoding a gene product that is cytoplasmic, membrane bound, or local acting, and whose function is one or more of: to mitigate antigen presenting cell activation and function; to mitigate graft attacking leukocyte activity or cytolytic function; to mitigate macrophage cytolytic function and phagocytosis of allograft cells; to induce apoptosis in graft attacking leukocytes; to mitigate local inflammatory proteins; and to protect against leukocyte-mediated apoptosis. The transgenes comprise two or more of the following genes: PD-L 1, HLAG or H2-M3, Cd47, Cd200, FASLG or Fasl, Ccl21 or Ccl21b, Mfge8, and Serpin B9 or Spi6.

Abstract: A device may transmit questionnaires to a set of client devices, wherein the questionnaires include a set of questions that relate to an internal entity experience attribute and/or an external entity experience attribute. The device may receive a set of questionnaire responses and correlate the set of questionnaire responses with contextual data relating to an entity. The device may process, using a machine learning model trained based on data relating to one or more other entities, the set of questionnaire responses and the contextual data to identify a set of features and a set of feature ranks. The device may select a subset of features based on the set of feature ranks and a set of influence thresholds. The device may generate a set of recommendations associated with the subset of features and communicate with one or more other devices to implement the set of recommendations.

Abstract: A platform for actuation of at least one industrial field device in an industrial installation having control software includes: an execution environment, in which the control software is runnable; and an external interface for communicating between the control software and the at least one industrial field device. The execution environment has virtual hardware which, from a point of view of the control software, behaves in a manner of the at least one industrial field device. A switching unit is connected between the virtual hardware and the external interface. The switching unit bidirectionally translates data, interchanged between the control software and the virtual hardware, for communication with the at least one industrial field device via the external interface.

Abstract: A system and method for energy harvesting in a data center has one or more collection devices, a thermoelectric device, and a controller for directing the operation of the thermoelectric device and other equipment in the data center. The waste heat generated by the servers in the data center is harnessed and directed into the thermoelectric device where the waste heat is converted to usable electrical energy under the direction of the controller. The recycled electrical energy is then combined with utility-input power and provided to the servers and other equipment in the data center for consumption.

Abstract: Unique systems, methods, techniques and apparatuses of remote monitoring for industrial systems are disclosed. One exemplary embodiment is a system for remote monitoring of an industrial plant, the system comprising a cloud-based computing component structured to store and to access a cloud portion of a federated information model; a plurality of industrial plant-based gateway components each structured to store and to access respective gateway portions of the federated information model, the respective gateway portions of the federated information model being isolated from access by the cloud-based computing component; and a plurality of industrial plant asset controllers, each of the asset controllers structured to store and to access respective asset portions of the federated information model.

Abstract: A system and method for monitoring operating conditions of an industrial installation system including a plurality of pieces of equipment. Each of the pieces of equipment includes a sensor and an electrically identifiable tag configured to identify the equipment. The sensors of each of the plurality of pieces of equipment provide an operating characteristic of the piece of equipment that is provided to an industrial equipment management system. The system is also configured to store the content of the electrically identifiable tag and to store a location identifier of each of plurality of pieces of equipment. Replacement of the identified defective equipment is made with replacement equipment having an identifier that uniquely identifies the replacement device and the location of the replacement device in the industrial installation system.

Abstract: A platform for actuation of at least one industrial field device in an industrial installation having control software includes: an execution environment, in which the control software is runnable; and an external interface for communicating between the control software and the at least one industrial field device. The execution environment has virtual hardware which, from a point of view of the control software, behaves in a manner of the at least one industrial field device. A switching unit is connected between the virtual hardware and the external interface. The switching unit bidirectionally translates data, interchanged between the control software and the virtual hardware, for communication with the at least one industrial field device via the external interface.

Abstract: Unique systems, methods, techniques and apparatuses of remote monitoring for industrial systems are disclosed. One exemplary embodiment is a system for remote monitoring of an industrial plant, the system comprising a cloud-based computing component structured to store and to access a cloud portion of a federated information model; a plurality of industrial plant-based gateway components each structured to store and to access respective gateway portions of the federated information model, the respective gateway portions of the federated information model being isolated from access by the cloud-based computing component; and a plurality of industrial plant asset controllers, each of the asset controllers structured to store and to access respective asset portions of the federated information model.

Abstract: A programmable logic controller for at least one field device in an industrial facility includes: a hardware platform on which an operating system runs, the operating system executing, in at least one process, at least one execution environment in which a control software containing the control logic of the programmable logic controller is runnable, the hardware platform including a main memory, a processor power, and communication resources; and a higher-level management system for running directly on the operating system and executing one or more execution environments in each case in its own sandbox, the management system including a resource manager for allocating to each sandbox access to the main memory, the processor power, and the communication resources of the hardware platform.

Abstract: A system and method for monitoring operating conditions of an industrial installation system including a plurality of pieces of equipment. Each of the pieces of equipment includes a sensor and an electrically identifiable tag configured to identify the equipment. The sensors of each of the plurality of pieces of equipment provide an operating characteristic of the piece of equipment that is provided to an industrial equipment management system. The system is also configured to store the content of the electrically identifiable tag and to store a location identifier of each of plurality of pieces of equipment. Replacement of the identified defective equipment is made with replacement equipment having an identifier that uniquely identifies the replacement device and the location of the replacement device in the industrial installation system.

Abstract: A system and method for energy harvesting in a data center has one or more collection devices, a thermoelectric device, and a controller for directing the operation of the thermoelectric device and other equipment in the data center. The waste heat generated by the servers in the data center is harnessed and directed into the thermoelectric device where the waste heat is converted to usable electrical energy under the direction of the controller. The recycled electrical energy is then combined with utility-input power and provided to the servers and other equipment in the data center for consumption.

Abstract: A system and method for energy harvesting in a data center has one or more collection devices, a thermoelectric device, and a controller for directing the operation of the thermoelectric device and other equipment in the data center. The waste heat generated by the servers in the data center is harnessed and directed into the thermoelectric device where the waste heat is converted to usable electrical energy under the direction of the controller. The recycled electrical energy is then combined with utility-input power and provided to the servers and other equipment in the data center for consumption.

Abstract: A power quality monitoring system and method standardizes power quality data obtained from heterogeneous devices such as power quality meters and other devices from various manufacturers. The power quality data is provided in a device independent and standardized format for use by web applications and other systems that manage and present the power quality data.

Abstract: A vented automatic dispending cap for use with a flexible container may generally include a body and a retainer cap attached to the body. A pressure chamber is formed between the body and retainer cap. A set of resilient spring members spaced around the body holds the retainer cap against the body, which seats a valve within a dispensing hole extending through the cap. When the container is squeezed, product in the container may be forced into the pressure chamber expanding the pressure chamber and unseating the valve, thereby allowing product to exit the dispensing opening. A lip seal around the upper circumferential edge of the body prevents fluid from leaking out of the sides of the chamber but allows air to enter the chamber for venting the flexible container.

Abstract: A vented automatic dispending cap for use with a flexible container may generally include a body and a retainer cap attached to the body. A pressure chamber is formed between the body and retainer cap. A set of resilient spring members spaced around the body holds the retainer cap against the body, which seats a valve within a dispensing hole extending through the cap. When the container is squeezed, product in the container may be forced into the pressure chamber expanding the pressure chamber and unseating the valve, thereby allowing product to exit the dispensing opening. A lip seal around the upper circumferential edge of the body prevents fluid from leaking out of the sides of the chamber but allows air to enter the chamber for venting the flexible container.

Abstract: A vented automatic dispending cap for use with a flexible container may generally include a body and a retainer cap attached to the body. A pressure chamber is formed between the body and retainer cap. A set of resilient spring members spaced around the body holds the retainer cap against the body, which seats a valve within a dispensing hole extending through the cap. When the container is squeezed, product in the container may be forced into the pressure chamber expanding the pressure chamber and unseating the valve, thereby allowing product to exit the dispensing opening. A lip seal around the upper circumferential edge of the body prevents fluid from leaking out of the sides of the chamber but allows air to enter the chamber for venting the flexible container.