Abstract: Disclosed herein are compositions and methods for topical delivery of EGFR inhibitors. In one embodiment, a topical anhydrous composition includes one or more EGFR inhibitors, one or more solvents, one or more gelling agents, and, optionally, one or more antioxidants. Also disclosed herein are methods to treat skin disorders using such compositions.

Abstract: A method enables a combustor for a gas turbine engine to be assembled. The method includes coupling an inner liner to an outer liner such that a combustion chamber is defined therebetween, wherein the outer liner is fabricated from a plurality of panels coupled together, and coupling an outer support radially outward from the outer liner such that an outer passageway is defined between the outer liner and the outer support, wherein the outer support is configured to channel cooling air from the outer passageway towards at least a portion of the outer liner.

Abstract: A method facilitates fabricating a gas turbine engine combustor. The method comprises coupling a venturi to a primary swirler, and coupling the venturi to a secondary swirler such that a gap is defined between a portion of the venturi and a portion of one of the primary swirler and the secondary swirler.