Patents by Inventor Jeffrey P. Whitten

Jeffrey P. Whitten has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compounds that modulate intracellular calcium
    Patent number: 11905248
    Abstract: Described herein are compounds and pharmaceutical compositions containing such compounds, which modulate the activity of store-operated calcium (SOC) channels. Also described herein are methods of using such SOC channel modulators, alone and in combination with other compounds, for treating diseases or conditions that would benefit from inhibition of SOC channel activity.
    Type: Grant
    Filed: October 15, 2019
    Date of Patent: February 20, 2024
    Assignee: CALCIMEDICA, INC.
    Inventors: Jeffrey P. Whitten, Yazhong Pei, Jianguo Cao, Zhijun Wang, Evan Rogers, Brian Dyck, Jonathan Grey
  • SYNTHESIS OF CRAC CHANNEL INHIBITORS
    Publication number: 20220056053
    Abstract: A convergent synthetic method for the production of CRAC channel inhibitors is described herein. The synthetic method provides a method for producing highly pure CRAC channel inhibitors for clinical testing.
    Type: Application
    Filed: November 4, 2021
    Publication date: February 24, 2022
    Inventors: Kenneth A. STAUDERMAN, Michael DUNN, Jeffrey P. WHITTEN, Evan ROGERS
  • COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM
    Publication number: 20200317617
    Abstract: Described herein are compounds and pharmaceutical compositions containing such compounds, which modulate the activity of store-operated calcium (SOC) channels. Also described herein are methods of using such SOC channel modulators, alone and in combination with other compounds, for treating diseases or conditions that would benefit from inhibition of SOC channel activity.
    Type: Application
    Filed: October 15, 2019
    Publication date: October 8, 2020
    Inventors: Jeffrey P. WHITTEN, Yazhong PEI, Jianguo CAO, Zhijun WANG, Evan ROGERS, Brian DYCK, Jonathan GREY
  • Compounds that modulate intracellular calcium
    Patent number: 10703722
    Abstract: Described herein are compounds and pharmaceutical compositions containing such compounds, which modulate the activity of store-operated calcium (SOC) channels. Also described herein are methods of using such SOC channel modulators, alone and in combination with other compounds, for treating diseases or conditions that would benefit from inhibition of SOC channel activity.
    Type: Grant
    Filed: July 21, 2015
    Date of Patent: July 7, 2020
    Assignee: CALCIMEDICA, INC.
    Inventors: Jeffrey P. Whitten, Yazhong Pei, Jianguo Cao, Zhijun Wang, Evan Rogers, Brian Dyck, Jonathan Grey
  • Compounds that modulate intracellular calcium
    Patent number: 10336738
    Abstract: Described herein are compounds and pharmaceutical compositions containing such compounds, which modulate the activity of store-operated calcium (SOC) channels. Also described herein are methods of using such SOC channel modulators, alone and in combination with other compounds, for treating diseases or conditions that would benefit from inhibition of SOC channel activity.
    Type: Grant
    Filed: June 3, 2015
    Date of Patent: July 2, 2019
    Assignee: CALCIMEDICA, INC.
    Inventors: Jeffrey P. Whitten, Yazhong Pei, Jianguo Cao, Zhijun Wang, Evan Rogers, Brian Dyck, Jonathan Grey
  • Compounds that modulate intracellular calcium
    Patent number: 10106529
    Abstract: Described herein are compounds and pharmaceutical compositions containing such compounds, which modulate the activity of store-operated calcium (SOC) channels. Also described herein are methods of using such SOC channel modulators, alone and in combination with other compounds, for treating diseases or conditions that would benefit from inhibition of SOC channel activity.
    Type: Grant
    Filed: May 20, 2016
    Date of Patent: October 23, 2018
    Assignee: CALCIMEDIA, INC.
    Inventors: Jeffrey P. Whitten, Jonathan Grey, Jianguo Cao, Zhijun Wang, Evan Rogers
  • Compounds that modulate intracellular calcium
    Patent number: 9856240
    Abstract: Described herein are compounds and pharmaceutical compositions containing such compounds, which modulate the activity of store-operated calcium (SOC) channels. Also described herein are methods of using such SOC channel modulators, alone and in combination with other compounds, for treating diseases or conditions that would benefit from inhibition of SOC channel activity.
    Type: Grant
    Filed: October 19, 2012
    Date of Patent: January 2, 2018
    Assignee: CALCIMEDICA, INC.
    Inventors: Jianguo Cao, Jeffrey P. Whitten, Zhijun Wang, Evan Rogers, Jonathan Grey
  • Compounds that modulate intracellular calcium
    Patent number: 9611263
    Abstract: Described herein are compounds and pharmaceutical compositions containing such compounds, which modulate the activity of store-operated calcium (SOC) channels. Also described herein are methods of using such SOC channel modulators, alone and in combination with other compounds, for treating diseases or conditions that would benefit from inhibition of SOC channel activity.
    Type: Grant
    Filed: October 7, 2014
    Date of Patent: April 4, 2017
    Assignee: CALCIMEDICA, INC.
    Inventors: Jianguo Cao, Zhijun Wang, Jonathan Grey, Evan Rogers, Jeffrey P. Whitten
  • COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM
    Publication number: 20170044152
    Abstract: Described herein are compounds and pharmaceutical compositions containing such compounds, which modulate the activity of store-operated calcium (SOC) channels. Also described herein are methods of using such SOC channel modulators, alone and in combination with other compounds, for treating diseases or conditions that would benefit from inhibition of SOC channel activity.
    Type: Application
    Filed: October 27, 2016
    Publication date: February 16, 2017
    Inventors: Evan ROGERS, Jianguo CAO, Zhijun WANG, Jonathan GREY, Jeffrey P. WHITTEN
  • Compounds that modulate intracellular calcium
    Patent number: 9512116
    Abstract: Described herein are compounds and pharmaceutical compositions containing such compounds, which modulate the activity of store-operated calcium (SOC) channels. Also described herein are methods of using such SOC channel modulators, alone and in combination with other compounds, for treating diseases or conditions that would benefit from inhibition of SOC channel activity.
    Type: Grant
    Filed: October 11, 2013
    Date of Patent: December 6, 2016
    Assignee: CALCIMEDICA, INC.
    Inventors: Evan Rogers, Jianguo Cao, Zhijun Wang, Jonathan Grey, Jeffrey P. Whitten
  • COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM
    Publication number: 20160304502
    Abstract: Described herein are compounds and pharmaceutical compositions containing such compounds, which modulate the activity of store-operated calcium (SOC) channels. Also described herein are methods of using such SOC channel modulators, alone and in combination with other compounds, for treating diseases or conditions that would benefit from inhibition of SOC channel activity.
    Type: Application
    Filed: May 20, 2016
    Publication date: October 20, 2016
    Inventors: Jeffrey P. WHITTEN, Jonathan GREY, Jianguo CAO, Zhijun WANG, Evan ROGERS
  • COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM
    Publication number: 20160229845
    Abstract: Described herein are compounds and pharmaceutical compositions containing such compounds, which modulate the activity of store-operated calcium (SOC) channels. Also described herein are methods of using such SOC channel modulators, alone and in combination with other compounds, for treating diseases or conditions that would benefit from inhibition of SOC channel activity.
    Type: Application
    Filed: October 7, 2014
    Publication date: August 11, 2016
    Inventors: Jianguo CAO, Zhijun WANG, Jonathan GREY, Evan ROGERS, Jeffrey P. WHITTEN
  • Compounds that modulate intracellular calcium
    Patent number: 9353099
    Abstract: Described herein are compounds and pharmaceutical compositions containing such compounds, which modulate the activity of store-operated calcium (SOC) channels. Also described herein are methods of using such SOC channel modulators, alone and in combination with other compounds, for treating diseases or conditions that would benefit from inhibition of SOC channel activity.
    Type: Grant
    Filed: June 17, 2015
    Date of Patent: May 31, 2016
    Assignee: CALCIMEDICA, INC.
    Inventors: Jeffrey P. Whitten, Yazhong Pei, Jianguo Cao, Zhijun Wang, Evan Rogers, Brian Dyck, Jonathan Grey
  • COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM
    Publication number: 20150361075
    Abstract: Described herein are compounds and pharmaceutical compositions containing such compounds, which modulate the activity of store-operated calcium (SOC) channels. Also described herein are methods of using such SOC channel modulators, alone and in combination with other compounds, for treating diseases or conditions that would benefit from inhibition of SOC channel activity.
    Type: Application
    Filed: June 17, 2015
    Publication date: December 17, 2015
    Inventors: Jeffrey P. WHITTEN, Yazhong PEI, Jianguo CAO, Zhijun WANG, Evan ROGERS, Brian DYCK, Jonathan GREY
  • COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM
    Publication number: 20150344469
    Abstract: Described herein are compounds and pharmaceutical compositions containing such compounds, which modulate the activity of store-operated calcium (SOC) channels. Also described herein are methods of using such SOC channel modulators, alone and in combination with other compounds, for treating diseases or conditions that would benefit from inhibition of SOC channel activity.
    Type: Application
    Filed: June 3, 2015
    Publication date: December 3, 2015
    Inventors: Jeffrey P. WHITTEN, Yazhong PEI, Jianguo CAO, Zhijun WANG, Evan ROGERS, Brian DYCK, Jonathan GREY
  • COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM
    Publication number: 20150322012
    Abstract: Described herein are compounds and pharmaceutical compositions containing such compounds, which modulate the activity of store-operated calcium (SOC) channels. Also described herein are methods of using such SOC channel modulators, alone and in combination with other compounds, for treating diseases or conditions that would benefit from inhibition of SOC channel activity.
    Type: Application
    Filed: July 21, 2015
    Publication date: November 12, 2015
    Inventors: Jeffrey P. WHITTEN, Yazhong PEI, Jianguo CAO, Zhijun WANG, Evan ROGERS, Brian DYCK, Jonathan GREY
  • COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM
    Publication number: 20150246909
    Abstract: Described herein are compounds and pharmaceutical compositions containing such compounds, which modulate the activity of store-operated calcium (SOC) channels. Also described herein are methods of using such SOC channel modulators, alone and in combination with other compounds, for treating diseases or conditions that would benefit from inhibition of SOC channel activity.
    Type: Application
    Filed: October 11, 2013
    Publication date: September 3, 2015
    Inventors: Evan Rogers, Jianguo Cao, Zhijun Wang, Jonathan Grey, Jeffrey P. Whitten
  • Compounds that modulate intracellular calcium
    Patent number: 9120751
    Abstract: Described herein are compounds and pharmaceutical compositions containing such compounds, which modulate the activity of store-operated calcium (SOC) channels. Also described herein are methods of using such SOC channel modulators, alone and in combination with other compounds, for treating diseases or conditions that would benefit from inhibition of SOC channel activity.
    Type: Grant
    Filed: August 16, 2013
    Date of Patent: September 1, 2015
    Assignee: CALCIMEDICA, INC.
    Inventors: Jeffrey P. Whitten, Yazhong Pei, Jianguo Cao, Zhijun Wang, Evan Rogers, Brian Dyck, Jonathan Grey
  • Compounds that modulate intracellular calcium
    Patent number: 9090612
    Abstract: Described herein are compounds and pharmaceutical compositions containing such compounds, which modulate the activity of store-operated calcium (SOC) channels. Also described herein are methods of using such SOC channel modulators, alone and in combination with other compounds, for treating diseases or conditions that would benefit from inhibition of SOC channel activity.
    Type: Grant
    Filed: May 1, 2014
    Date of Patent: July 28, 2015
    Assignee: CALCIMEDICA, INC.
    Inventors: Jeffrey P. Whitten, Yazhong Pei, Jianguo Cao, Zhijun Wang, Evan Rogers, Brian Dyck, Jonathan Grey
  • Compounds that modulate intracellular calcium
    Patent number: 9079891
    Abstract: Described herein are compounds and pharmaceutical compositions containing such compounds, which modulate the activity of store-operated calcium (SOC) channels. Also described herein are methods of using such SOC channel modulators, alone and in combination with other compounds, for treating diseases or conditions that would benefit from inhibition of SOC channel activity.
    Type: Grant
    Filed: August 26, 2011
    Date of Patent: July 14, 2015
    Assignee: CALCIMEDICA, INC.
    Inventors: Jeffrey P. Whitten, Yazhong Pei, Jianguo Cao, Zhijun Wang, Evan Rogers, Brian Dyck, Jonathan Grey