Abstract: The invention relates to a novel group of compounds of Formula (I) or salts thereof: wherein Y, Z1, Z2, R1, R4, R5 and n are as described in the specification, which may be useful in the treatment or prevention of a disease or medical condition mediated through protein kinase B (PKB) such as cancer. The invention also relates to pharmaceutical compositions comprising said compounds, methods of treatment of diseases mediated by PKB using said compounds and methods for preparing compounds of Formula (I).

Abstract: A land preparation apparatus includes a rotatable tool including a body and a plurality of tool assemblies disposed on an outer surface of the body. The land preparation apparatus also includes a housing including a first end, a second end, and a framework extending between the first and second ends. Ends of the rotatable tool are rotatably connected to the first and second ends. The framework has an interior surface that extends along at least a portion of the width of the rotatable tool. The interior surface has two or more interior surface sections across its width, with each of the interior surface sections defining a corresponding chamber section. The interior surface combines with a periphery of the rotatable tool, the first end, and the second end to define a chamber.

Abstract: A land preparation apparatus includes a rotatable tool including a body and a plurality of tool assemblies disposed on an outer surface of the body. The land preparation apparatus also includes a housing including a first end, a second end, and a framework extending between the first and second ends. Ends of the rotatable tool are rotatably connected to the first and second ends. The framework has an interior surface that extends along at least a portion of the width of the rotatable tool. The interior surface combines with a periphery of the rotatable tool, the first end, and the second end to define a chamber. The land preparation apparatus also includes one or more chamber inserts releasably attached to the interior surface, wherein at least a portion of each of the one or more chamber inserts resides in the chamber.

Abstract: A land preparation tool includes a cutting surface having a blade and a mounting interface opposite the cutting surface. The mounting interface of the land preparation tool is configured to detachably connect to a tool holder having a top surface, an end surface, a mounting surface opposite the end surface, and opposing first and second side surfaces extending between the end surface and the mounting surface. The mounting surface has an apex extending downwardly from the top surface and first and second mounting faces. The first mounting face extends inwardly from the first side surface toward the apex and the second mounting face extends inwardly from the second side surface toward the apex.

Abstract: A land preparation tool includes a tool body having a longitudinal axis, a cutting surface having a distal end and a blade positioned at the distal end, and a mounting interface disposed on the tool body opposite the cutting surface. The mounting interface has an apex extending along the mounting interface parallel to the longitudinal axis, a mounting surface extending from the apex, another mounting surface extending from the apex, and an opening. A channel extends from the opening of the mounting interface into the tool body.

Abstract: A land preparation tool includes a tool body having a cutting surface, mounting surfaces disposed on the tool body opposite the cutting surface, and opposing side surfaces each extending between the cutting surface and a different one of the mounting surfaces. One mounting surface angles inwardly from a distal edge of a side surface toward the tool body. Another mounting surface angles inwardly from a distal edge of the other side surface toward the tool body. An opening is disposed on the tool body opposite the cutting surface and between the mounting surfaces.

Abstract: A land preparation machine includes a land preparation apparatus connected to a lift assembly of a vehicle. The land preparation apparatus has a rotatable drum and a plurality of tools assemblies disposed thereon. A tool assembly of the plurality of tool assemblies includes a tool holder and a tool attached thereto. The tool includes a tool body having a cutting surface disposed on a side of the tool body, an apex disposed on a different side of the tool body opposite the cutting surface, and tool mounting surfaces disposed on the side of the tool body opposite the cutting surface. One tool mounting surface extends outwardly from the apex at an angle toward the cutting surface. Another tool mounting surface extends outwardly from the apex, opposite the other tool mounting surface, at an angle toward the cutting surface. Other embodiments are described and claimed.

Abstract: A land preparation tool includes a tool body having a cutting surface, mounting surfaces disposed on the tool body opposite the cutting surface, and opposing side surfaces each extending between the cutting surface and a different one of the mounting surfaces. One mounting surface angles inwardly from a distal edge of a side surface toward the tool body. Another mounting surface angles inwardly from a distal edge of the other side surface toward the tool body. An opening is disposed on the tool body opposite the cutting surface and between the mounting surfaces. Other embodiments are described and claimed.

Abstract: A land preparation machine includes a land preparation apparatus connected to a lift assembly of a vehicle. The land preparation apparatus has a rotatable drum and a plurality of tools assemblies disposed thereon. A tool assembly of the plurality of tool assemblies includes a tool holder and a tool attached thereto. The tool includes a tool body having a cutting surface disposed on a side of the tool body, an apex disposed on a different side of the tool body opposite the cutting surface, and tool mounting surfaces disposed on the side of the tool body opposite the cutting surface. One tool mounting surface extends outwardly from the apex at an angle toward the cutting surface. Another tool mounting surface extends outwardly from the apex, opposite the other tool mounting surface, at an angle toward the cutting surface. Other embodiments are described and claimed.

Abstract: A land preparation tool includes a tool body having a cutting surface, a mounting surface, an opening, and a channel. The cutting surface has a blade positioned at a distal end thereof. The mounting surface has a non-planar profile and is disposed on the tool body opposite the cutting surface. The opening is disposed on the mounting surface and the channel extends from the opening at least partially into the tool body. Other embodiments are described and claimed.

Abstract: A land preparation tool includes a tool body having a cutting surface, a mounting surface, an opening, and a channel. The cutting surface has a blade positioned at a distal end thereof. The mounting surface has a non-planar profile and is disposed on the tool body opposite the cutting surface. The opening is disposed on the mounting surface and the channel extends from the opening at least partially into the tool body. Other embodiments are described and claimed.

Abstract: A land preparation tool includes a tool body having a longitudinal axis; a cutting surface having a distal end and a blade positioned at the distal end; a mounting surface disposed on the tool body opposite the cutting surface, the mounting surface having an apex extending along about half of the mounting surface parallel to the longitudinal axis, a first mounting surface extending from the apex, a second mounting surface extending from the apex, and an opening disposed on the mounting surface; and a channel extending from the opening only partially into the tool body

Abstract: A land preparation tool includes a tool body having a longitudinal axis; a cutting surface having a distal end and first and second blades positioned at the distal end; a mounting surface disposed on the tool body opposite the cutting surface, the mounting surface having an apex extending along about half of the mounting surface parallel to the longitudinal axis, a first mounting surface extending from the apex, a second mounting surface extending from the apex, and a recess disposed into the mounting surface; and a channel extending from the recess only partially into the tool body.

Abstract: A land preparation tool includes a tool body having a longitudinal axis, wherein the tool body includes a cutting surface and a mounting surface disposed on the tool body opposite the cutting surface, wherein the mounting surface includes an apex that extends along about half of the mounting surface parallel to the longitudinal axis and first and second side mounting surfaces that extend from the apex; a blade disposed on the same side of the tool body as the cutting surface; and a channel disposed into the mounting surface and extending into the tool body.