Abstract: The present invention relates to Map4K1 inhibitors of formula (I) (I), wherein A, E, G, Q, R1, R2 and R4 have the same meaning as defined in the description, to pharmaceutical compositions and combinations comprising the compounds according to the invention, and to the prophylactic and therapeutic use of the inventive compounds, respectively to the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular for neoplastic disorders, respectively cancer or conditions with dysregulated immune responses or other disorders associated with aberrant MAP4K1 signaling, as a sole agent or in combination with other active ingredients.

Abstract: An integrated active control system includes gaming devices, a server, and a network connecting the server and gaming devices. The gaming devices include gaming terminals and gaming tables. The integrated active control system aggregates gaming transaction information from the gaming devices and determines, for example, the effectiveness of the gaming establishment's floor configuration. Based on this effectiveness determination, at least one of the gaming devices are instructed to change their configuration. Staffing information may also be considered and reconfigured. The integrated active control system further monitors and configures gaming chips. The gaming chips are programmable, and may store monetary chip value and chip identification information. The programmable gaming chips are monitored for tracking the wagers made with the chips as well as for detecting their location.

Abstract: A computing system can generate data for rendering an interactive graphical user interface, allow a user to input transaction parameters, receive a vehicle identifier associated with an individual, determine that an existing vehicle is at a service location, and provide an indication that the first individual is a qualifying individual and that the existing vehicle is at the service location.

Abstract: Systems and methods for generating a video of a user-defined virtual reality scene are disclosed. Exemplary implementations may: obtain a scene definition; obtain camera information for multiple virtual cameras to be used in generating a two-dimensional presentation of the virtual reality scene; execute a simulation of the virtual reality scene from the scene definition for at least a portion of the scene duration; obtain camera timing instructions specifying which of the virtual cameras should be used to generate the two-dimensional presentation of the virtual reality scene as a function of progress through the scene duration; generate the two-dimensional presentation of the virtual reality scene in accordance with the camera timing instructions and the camera information.

Abstract: A visual discovery tool for automotive manufacturing with network encryption, data conditioning, and prediction can include an extraction device configured to receive data records from application-specific file source databases. The tool can further include a vehicle alert database that receives the vehicle records from the plurality of extraction databases. The visual discovery tool can include at least one hardware processor in communication with the extraction device and the vehicle alert database. The tool can be configured to selectively restrict access to an interactive display based on whether a client device receives authorization credentials.

Abstract: A razor blade including a substrate with a coating joined to the substrate defining a coated blade. The coated blade including a cutting edge being defined by a blade tip having a tip radius of from 50 to 350 angstroms. The coated blade having a pair of first facets extending from the blade tip and a pair of second facets extending from the respective first facets, a facet angle from 90° to 135°, a facet width from 0.38 micrometers to 0.65 micrometers a wedge angle from 5° to 30°, and a thickness of between 0.8 and 1.5 micrometers measured at a distance of 1 micrometer from the blade tip.

Abstract: This invention relates to a novel application of hard, low friction aluminum magnesium boride (AlMgB14, also known as BAM) based ceramic coatings to surfaces of razor components and in particular to blade edges of razor blades. On razor blade edges, these coatings may elevate blade performance, while also simplifying the manufacturing process.

Abstract: The present invention relates to protein-inhibitory substituted pyrrolopyridine derivatives of formula (I), in which A, X, R1, R2a, R2b, R3a, R3b, R4a and R4b are as defined herein, to pharmaceutical compositions and combinations comprising the compounds according to the invention, and to the prophylactic and therapeutic use of the inventive compounds, respectively to the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular for neoplastic disorders, respectively cancer or conditions with dysregulated immune responses or other disorders associated with aberrant MAP4K1 signaling, as a sole agent or in combination with other active ingredients.

Abstract: A computing system can generate data for rendering an interactive graphical user interface, allow a user to input transaction parameters, receive a vehicle identifier associated with an individual, determine that an existing vehicle is at a service location, and provide an indication that the first individual is a qualifying individual and that the existing vehicle is at the service location.

Abstract: The present invention relates to protein-inhibitory substituted pyrrolopyridine derivatives of formula (I) in which A, X, R1a, R1b, R2, R3a, R3b, R4a and R4b are as defined herein, to pharmaceutical compositions and combinations comprising the compounds according to the invention, and to the prophylactic and therapeutic use of the inventive compounds, respectively to the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular for neoplastic disorders, respectively cancer or conditions with dysregulated immune responses or other disorders associated with aberrant MAP4K1 signaling, as a sole agent or in combination with other active ingredients.

Abstract: The present disclosure involves systems, software, and computer implemented methods for providing credit card customers with an offer to finance large, unexpected, or general expenditures on a set installment plan associated with a fixed interest rate or fee. The rate or fee associated with the offer can be a flat one-time fee, a fixed interest rate, or a combination thereof. In some instances, a variable interest rate can be offered. In some instances, the fee can be an ongoing small or nominal fee added to each repayment over a period of time.

Abstract: A computing system can generate data for rendering an interactive graphical user interface, allow a user to input transaction parameters, receive a vehicle identifier associated with an individual, determine that an existing vehicle is at a service location, and provide an indication that the first individual is a qualifying individual and that the existing vehicle is at the service location.

Abstract: A computing system can generate data for rendering an interactive graphical user interface, allow a user to input transaction parameters, receive a vehicle identifier associated with an individual, determine that an existing vehicle is at a service location, and provide an indication that the first individual is a qualifying individual and that the existing vehicle is at the service location.

Abstract: In accordance with at least one embodiment, a method, apparatus, and communication system provide intra-symbol multi-dimensional modulation (ISMM). A modulator can be provided modulate data according to ISMM for transmission.

Abstract: A visual discovery tool for automotive manufacturing with network encryption, data conditioning, and prediction can include an extraction device configured to receive data records from application-specific file source databases. The tool can further include a vehicle alert database that receives the vehicle records from the plurality of extraction databases. The visual discovery tool can include at least one hardware processor in communication with the extraction device and the vehicle alert database. The tool can be configured to selectively restrict access to an interactive display based on whether a client device receives authorization credentials.

Abstract: A visual discovery tool for automotive manufacturing with network encryption, data conditioning, and prediction can include an extraction device configured to receive data records from application-specific file source databases. The tool can further include a vehicle alert database that receives the vehicle records from the plurality of extraction databases. The visual discovery tool can include at least one hardware processor in communication with the extraction device and the vehicle alert database. The tool can be configured to selectively restrict access to an interactive display based on whether a client device receives authorization credentials.

Abstract: The present disclosure describes computer hardware, software, systems and methods for evaluating the effect of planned, future or hypothetical incentive programs on a financial arrangement that could be offered to customers such as automobile customers. Computer hardware and modules are disclosed that can store, receive, display, or calculate customer data corresponding to financial terms of current agreements of one or more customers and hypothetical incentive data, store, receive, display, or generate potential customer pools that include customers for which a replacement product and a replacement financial agreement has financial terms substantially similar to financial terms of a current product and current financial agreement, and generate a summary report that includes the customers in the potential customer pool.

Abstract: A razor blade including a substrate with a coating joined to the substrate defining a coated blade. The coated blade including a cutting edge being defined by a blade tip having a tip radius of from 50 to 350 angstroms. The coated blade having a pair of first facets extending from the blade tip and a pair of second facets extending from the respective first facets, a facet angle from 90° to 135°, a facet width from 0.38 micrometers to 0.65 micrometers a wedge angle from 5° to 30°, and a thickness of between 0.8 and 1.5 micrometers measured at a distance of 1 micrometer from the blade tip.

Abstract: The invention provides seed and plants of the hybrid corn variety designated 36364973. The invention thus relates to the plants, seeds and tissue cultures of the variety 36364973, and to methods for producing a corn plant produced by crossing a corn plant of variety 36364973 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety 36364973.

Abstract: In accordance with at least one embodiment, a method, apparatus, and communication system provide intra-symbol multi-dimensional modulation (ISMM). A modulator can be provided modulate data according to ISMM for transmission.