Patents by Inventor Jeffrey Yen Pan

Jeffrey Yen Pan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • High throughput, optical method and system for determining the effect of a test substance on non-contiguous living cells
    Patent number: 9053352
    Abstract: A rapid and efficient method and apparatus for detecting electrophysiologic, proarrhythmic, contractile, and other effects of substances such as compounds and drugs in native cellular cardiac preparations, the preparations representing an integrated cell-based pharmacologic response is disclosed. More specifically, a method to (1) rapidly and efficiently detect and verify the effects of chemicals, compounds and drugs on cardiac repolarization, contractility, and excitability using optically based techniques and customized simulation protocols, and (2) rapidly and efficiently screen and select compounds for electrophysiologic and proarrhythmic effects on cardiac myocytes is disclosed.
    Type: Grant
    Filed: November 11, 2011
    Date of Patent: June 9, 2015
    Assignee: AbbVie Inc.
    Inventors: Jonathan D. Trumbull, Gary A. Gintant, Stanislaw Kantor, Jeffrey Yen Pan, Gilbert J. Diaz, Jonathon Green, Zhi Su, Jeffrey A. Olson
  • METHODS FOR INCREASING THE EFFICIENCY OF HYBRIDOMA GENERATION
    Publication number: 20140199319
    Abstract: Disclosed herein are methods for improving the efficiency of the production of hybridomas, e.g., through enrichment of IgG expressing B cells. Also disclosed are hybridoma compositions produced using these methods as well as methods for producing antibodies with the hybridomas.
    Type: Application
    Filed: December 13, 2013
    Publication date: July 17, 2014
    Applicant: AbbVie, Inc.
    Inventors: Jane SEAGAL, Eve H. BARLOW, Chung-Ming HSIEH, Jeffrey Yen PAN, Shawn M. JENNINGS, Mary R. LEDDY, Archana B. THAKUR
  • HIGH THROUGHPUT, OPTICAL METHOD AND SYSTEM FOR DETERMINING THE EFFECT OF A TEST SUBSTANCE ON NON-CONTIGUOUS LIVING CELLS
    Publication number: 20120134570
    Abstract: A rapid and efficient method and apparatus for detecting electrophysiologic, proarrhythmic, contractile, and other effects of substances such as compounds and drugs in native cellular cardiac preparations, the preparations representing an integrated cell-based pharmacologic response is disclosed. More specifically, a method to (1) rapidly and efficiently detect and verify the effects of chemicals, compounds and drugs on cardiac repolarization, contractility, and excitability using optically based techniques and customized simulation protocols, and (2) rapidly and efficiently screen and select compounds for electrophysiologic and proarrhythmic effects on cardiac myocytes is disclosed.
    Type: Application
    Filed: November 11, 2011
    Publication date: May 31, 2012
    Applicant: ABBOTT LABORATORIES
    Inventors: Jonathan D. Trumbull, Gary A. Gintant, Stanislaw Kantor, Jeffrey Yen Pan, Gilbert J. Diaz, Jonathon Green, Zhi Su, Jeffrey A. Olson