Patents by Inventor Jennifer Lapira

Jennifer Lapira has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Thermostable type-A DNA polymerase mutants with increased polymerization rate and resistance to inhibitors
    Patent number: 9523085
    Abstract: The present invention provides mutants of DNA polymerases having an increased rate of incorporation of nucleotides into nucleic acids undergoing polymerization and having an enhanced resistance to inhibitors of DNA polymerase activity. The mutant polymerases are well suited for fast PCR applications, for PCR amplification of targets in samples that contain inhibitors of wild-type polymerases, and for fast PCR amplification of samples containing DNA polymerase inhibitors. In exemplary embodiments, the mutants are mutants of Taq DNA polymerase.
    Type: Grant
    Filed: August 2, 2010
    Date of Patent: December 20, 2016
    Assignee: Agilent Technologies Inc.
    Inventors: Holly Hogrefe, Michelle Cayouette, Jeffrey Fox, Connie J. Hansen, Jennifer Lapira, Bahram Arezi, Nancy McKinney
  • THERMOSTABLE TYPE-A DNA POLYMERASE MUTANTS WITH INCREASED POLYMERIZATION RATE AND RESISTANCE TO INHIBITORS
    Publication number: 20110027833
    Abstract: The present invention provides mutants of DNA polymerases having an increased rate of incorporation of nucleotides into nucleic acids undergoing polymerization and having an enhanced resistance to inhibitors of DNA polymerase activity. The mutant polymerases are well suited for fast PCR applications, for PCR amplification of targets in samples that contain inhibitors of wild-type polymerases, and for fast PCR amplification of samples containing DNA polymerase inhibitors. In exemplary embodiments, the mutants are mutants of Taq DNA polymerase.
    Type: Application
    Filed: August 2, 2010
    Publication date: February 3, 2011
    Inventors: Holly Hogrefe, Michelle Cayouette, Jeffrey Fox, Connie J. Hansen, Jennifer Lapira, Bahram Arezi, Nancy McKinney