Patents by Inventor Jennipher Grudzien
Jennipher Grudzien has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9981264Abstract: Methods and systems are provided for a lateral flow test device. In one example a lateral flow test device may include a housing comprising an upper first portion and a lower second portion, the lower second portion further including a planar surface, a nitrocellulose matrix strip, the strip disposed on the planar surface, and one or more ligand regions included in the strip, the ligand regions comprising one or more ligands. The strip may be formed from a liquid polymer mixture dispensed onto the planar surface via a dispensing device positioned vertically above the planar surface.Type: GrantFiled: November 3, 2015Date of Patent: May 29, 2018Assignee: Grace Bio-Labs, Inc.Inventors: Charles Greef, Joshua Snider, Steven Weaver, Jennipher Grudzien
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Publication number: 20160121323Abstract: Methods and systems are provided for a lateral flow test device. In one example a lateral flow test device may include a housing comprising an upper first portion and a lower second portion, the lower second portion further including a planar surface, a nitrocellulose matrix strip, the strip disposed on the planar surface, and one or more ligand regions included in the strip, the ligand regions comprising one or more ligands. The strip may be formed from a liquid polymer mixture dispensed onto the planar surface via a dispensing device positioned vertically above the planar surface.Type: ApplicationFiled: November 3, 2015Publication date: May 5, 2016Inventors: Charles Greef, Joshua Snider, Steven Weaver, Jennipher Grudzien
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Patent number: 8287822Abstract: A reaction surface array diagnostic apparatus and method of making the same includes a substrate carrying a plurality of reaction surfaces, a plate and a gasket, each having a plurality of through bores, alignable with one of the reaction surfaces and forming a fluid tight well about each reaction surface when the gasket and the plate are sealingly affixed to the substrate to form a stack. Clamp members engage opposite side edges of a stack to compress the gasket. A plurality of side-by-side disposed clamped stacks of plates, gaskets and substrates are mounted in a tray in the standard footprint of a microtitre plate. Alternately, the plate and the gasket are combined into a single plate formed of a flexible material having an adhesive on one surface.Type: GrantFiled: May 14, 2010Date of Patent: October 16, 2012Assignee: Grace Bio-Labs, Inc.Inventors: Jennipher Grudzien, Charles M. McGrath
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Patent number: 8034306Abstract: A reaction surface array diagnostic apparatus includes a substrate carrying a plurality of reaction surfaces and, a plate having a plurality of wells, alignable with one of the reaction surfaces and forming a fluid tight well about each reaction surface when the plate and the substrate are sealingly affixed to each other in a frame. The plate is formed of a flexible material which may have an adhesive on one surface. Interlocking latch members are formed on the plate and the frame for releasably latching the plate and the frame in a position for sealing attachment to the substrate.Type: GrantFiled: September 28, 2005Date of Patent: October 11, 2011Assignee: Grace Bio-Labs, Inc.Inventors: Jennipher Grudzien, Charles McGrath
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Publication number: 20100267590Abstract: A reaction surface array diagnostic apparatus and method of making the same includes a substrate carrying a plurality of reaction surfaces, a plate and a gasket, each having a plurality of through bores, alignable with one of the reaction surfaces and forming a fluid tight well about each reaction surface when the gasket and the plate are sealingly affixed to the substrate to form a stack. Clamp members engage opposite side edges of a stack to compress the gasket. A plurality of side-by-side disposed clamped stacks of plates, gaskets and substrates are mounted in a tray in the standard footprint of a microtitre plate. Alternately, the plate and the gasket are combined into a single plate formed of a flexible material having an adhesive on one surface.Type: ApplicationFiled: May 14, 2010Publication date: October 21, 2010Applicant: GRACE BIO-LABS, INC.Inventors: Jennipher Grudzien, Charles M. McGrath
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Patent number: 7736594Abstract: A reaction surface array diagnostic apparatus and method of making the same includes a substrate carrying a plurality of reaction surfaces and a gasket having a plurality of through bores, each alignable with one of the reaction surfaces and forming a fluid tight well about each reaction surface when the gasket is sealingly affixed to the substrate. In one aspect, the gasket and the substrate are mounted in a support. In another aspect, a plate having a plurality of through bores is mountable on the gasket and substrate. Clamp members engage opposite side edges of the plate, the gasket and the substrate.Type: GrantFiled: January 22, 2003Date of Patent: June 15, 2010Assignee: Grace Bio-Labs, Inc.Inventors: Jennipher Grudzien, Charles M. NcGrath
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Patent number: 7731909Abstract: A reaction surface array diagnostic apparatus and method of making the same includes a substrate carrying a plurality of reaction surfaces, a plate and a gasket, each having a plurality of through bores, alignable with one of the reaction surfaces and forming a fluid tight well about each reaction surface when the gasket and the plate are sealingly affixed to the substrate to form a stack. Clamp members engage opposite side edges of a stack to compress the gasket. A plurality of side-by-side disposed clamped stacks of plates, gaskets and substrates are mounted in a tray in the standard footprint of a microtiter plate. Alternately, the plate and the gasket are combined into a single plate formed of a flexible material having an adhesive on one surface.Type: GrantFiled: February 20, 2004Date of Patent: June 8, 2010Assignee: Grace Bio-Labs, Inc.Inventors: Jennipher Grudzien, Charles M. McGrath
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Patent number: 7063979Abstract: The invention describes a process for preparing a microtiter-microarray device that includes a bottomless microtiter plate attached to the first side of one or more substrates with microarrays of materials attached thereto. The microtiter plate and the one or more substrates are attached through one or more gaskets. Preferably, the microtiter plate is attached to one face of the one or more gaskets by an irreversible water-tight seal, and the first side of the one or more substrates is attached to the opposite face of the one or more gaskets by a reversible, water-tight seal.Type: GrantFiled: June 13, 2002Date of Patent: June 20, 2006Assignees: Grace Bio Labs., Inc., President and Fellows of Harvard CollegeInventors: Gavin MacBeath, Jennipher Grudzien
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Publication number: 20030026739Abstract: The invention describes a process for preparing a microtiter-microarray device that includes a bottomless microtiter plate attached to the first side of one or more substrates with microarrays of materials attached thereto. The microtiter plate and the one or more substrates are attached through one or more gaskets. Preferably, the microtiter plate is attached to one face of the one or more gaskets by an irreversible water-tight seal, and the first side of the one or more substrates is attached to the opposite face of the one or more gaskets by a reversible, water-tight seal.Type: ApplicationFiled: June 13, 2002Publication date: February 6, 2003Inventors: Gavin MacBeath, Jennipher Grudzien
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Patent number: 5192503Abstract: A probe clip for in situ assay of tissue sections in the form of a plate having a first seal member mounted thereon and forming an interior cavity on the plate. In one embodiment, a second seal member is mounted interiorly of the first seal member and divides the interior cavity into first and second fluid communicatable surfaces, with a probe dryingly attached to the plate and disposed on the second mixing surface. The plate is joined to a slide carrying a tissue section and a reactant fluid such to form fluid communicatable reaction and mixing chambers. Successive rotations of the joined plate and slide causes the reactant fluid to initially flow to the mixing chamber and release the probe, before the probe flows to the reaction chamber for reaction with the tissue section. In another embodiment, a time-release material covers the probe mounted on a plate having a single chamber. The reactant fluid hydrolyzes the time-release material to release the probe for reaction with the tissue.Type: GrantFiled: May 23, 1990Date of Patent: March 9, 1993Inventors: Charles M. McGrath, Jennipher Grudzien