Patents by Inventor Jens Ackerstaff
Jens Ackerstaff has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230024752Abstract: The invention relates to substituted oxopyridine derivatives and to processes for their preparation, and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular cardiovascular disorders, preferably thrombotic or thromboembolic disorders, and oedemas, and also ophthalmic disorders.Type: ApplicationFiled: October 18, 2021Publication date: January 26, 2023Inventors: Eloisa JIMENEZ NUNEZ, Jens ACKERSTAFF, Susanne ROEHRIG, Alexander HILLISCH, Katharina MEIER, Stefan HEITMEIER, Adrian TERSTEEGEN, Jan STAMPFUSS, Pascal ELLERBROCK, Daniel MEIBOM, Dieter LANG
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Publication number: 20220409618Abstract: The present application relates to novel substituted 5-fluoro-1H-pyrazolopyridines, to processes for their preparation, to their use alone or in combinations for the treatment and/or prophylaxis of diseases, and to their use for producing medicaments for the treatment and/or prophylaxis of diseases, in particular for the treatment and/or prophylaxis of cardiovascular disorders.Type: ApplicationFiled: August 18, 2022Publication date: December 29, 2022Applicant: Adverio Pharma GmbHInventors: Markus Follmann, Johannes-Peter Stasch, Gorden Redlich, Jens Ackerstaff, Nils Griebenow, Walter Kroh, Andreas Knorr, Eva-Maria Becker, Frank Wunder, Volkhart Min-Jian Li, Elke Hartmann, Joachim Mittendorf, Karl-Heinz Schlemmer, Rolf Jautelat, Donald Bierer
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Patent number: 11439642Abstract: The present application relates to novel substituted 5-fluoro-1H-pyrazolopyridines, to processes for their preparation, to their use alone or in combinations for the treatment and/or prophylaxis of diseases, and to their use for producing medicaments for the treatment and/or prophylaxis of diseases, in particular for the treatment and/or prophylaxis of cardiovascular disorders.Type: GrantFiled: July 2, 2020Date of Patent: September 13, 2022Assignee: ADVERIO PHARMA GMBHInventors: Markus Follmann, Johannes-Peter Stasch, Gorden Redlich, Jens Ackerstaff, Nils Griebenow, Walter Kroh, Andreas Knorr, Eva-Maria Becker, Frank Wunder, Volkhart Min-Jian Li, Elke Hartmann, Joachim Mittendorf, Karl-Heinz Schlemmer, Rolf Jautelat, Donald Bierer
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Publication number: 20220144848Abstract: The invention relates to substituted oxopyridine derivatives and to processes for their preparation, and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular vascular disorders, preferably thrombotic or thromboembolic disorders and/or thrombotic or thromboembolic complications.Type: ApplicationFiled: December 18, 2019Publication date: May 12, 2022Inventors: Susanne ROEHRIG, Sebastian ESSIG, Pascal ELLERBROCK, Sonja ANLAUF, Thomas NEUBAUER, Alexander HILLISCH, Katharina MEIER, Stefan HEITMEIER, Adrian TERSTEEGEN, Martina SCHAFER, Jan STAMPFUSS, Dieter LANG, Eloisa JIMENEZ NUNEZ, Jens ACKERSTAFF, Henrik TELLER, Zengqiang ZOU, Ping LIU, Xianghai MENG, Frank LESSMANN
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Patent number: 11180471Abstract: The invention relates to substituted oxopyridine derivatives and to processes for their preparation, and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular cardiovascular disorders, preferably thrombotic or thromboembolic disorders, and oedemas, and also ophthalmic disorders.Type: GrantFiled: August 8, 2019Date of Patent: November 23, 2021Assignee: Bayer Pharma AktiengesellschaftInventors: Eloisa Jimenez Nunez, Jens Ackerstaff, Susanne Roehrig, Alexander Hillisch, Katharina Meier, Stefan Heitmeier, Adrian Tersteegen, Jan Stampfuss, Pascal Ellerbrock, Daniel Meibom, Dieter Lang
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Publication number: 20200397785Abstract: The present application relates to novel substituted 5-fluoro-1H-pyrazolopyridines, to processes for their preparation, to their use alone or in combinations for the treatment and/or prophylaxis of diseases, and to their use for producing medicaments for the treatment and/or prophylaxis of diseases, in particular for the treatment and/or prophylaxis of cardiovascular disorders.Type: ApplicationFiled: July 2, 2020Publication date: December 24, 2020Applicant: Adverio Pharma GmbHInventors: Markus Follmann, Johannes-Peter Stasch, Gorden Redlich, Jens Ackerstaff, Nils Griebenow, Walter Kroh, Andreas Knorr, Eva-Maria Becker, Frank Wunder, Volkhart Min-Jian Li, Elke Hartmann, Joachim Mittendorf, Karl-Heinz Schlemmer, Rolf Jautelat, Donald Bierer
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Patent number: 10736896Abstract: The present application relates to novel substituted 5-fluoro-1H-pyrazolopyridines, to processes for their preparation, to their use alone or in combinations for the treatment and/or prophylaxis of diseases, and to their use for producing medicaments for the treatment and/or prophylaxis of diseases, in particular for the treatment and/or prophylaxis of cardiovascular disorders.Type: GrantFiled: May 16, 2018Date of Patent: August 11, 2020Assignee: ADVERIO PHARMA GMBHInventors: Markus Follmann, Johannes-Peter Stasch, Gorden Redlich, Jens Ackerstaff, Nils Griebenow, Walter Kroh, Andreas Knorr, Eva-Maria Becker, Frank Wunder, Volkhart Min-Jian Li, Elke Hartmann, Joachim Mittendorf, Karl-Heinz Schlemmer, Rolf Jautelat, Donald Bierer
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Publication number: 20200061063Abstract: The present application relates to novel bicyclically substituted uracil derivatives, to processes for preparation thereof, to the use thereof alone or in combinations for treatment and/or prophylaxis of diseases, and to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases.Type: ApplicationFiled: April 2, 2019Publication date: February 27, 2020Applicant: Bayer Pharma AktiengesellschaftInventors: Chantal FÜRSTNER, Jens ACKERSTAFF, Alexander STRAUB, Heinrich MEIER, Hanna TINEL, Katja ZIMMERMANN, Adrian TERSTEEGEN, Dmitry ZUBOV, Raimund KAST, Jens SCHAMBERGER, Martina SCHÄFER, Kirsten BÖRNGEN
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Publication number: 20190367478Abstract: The invention relates to substituted oxopyridine derivatives and to processes for their preparation, and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular cardiovascular disorders, preferably thrombotic or thromboembolic disorders, and oedemas, and also ophthalmic disorders.Type: ApplicationFiled: August 8, 2019Publication date: December 5, 2019Inventors: Eloisa JIMENEZ NUNEZ, Jens ACKERSTAFF, Susanne RÖEHRIG, Alexander HILLISCH, Katharina MEIER, Stefan HEITMEIER, Adrian TERSTEEGEN, Jan STAMPFUSS, Pascal ELLERBROCK, Daniel MEIBOM, Dieter LANG
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Patent number: 10421742Abstract: The invention relates to substituted oxopyridine derivatives and to processes for their preparation, and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular cardiovascular disorders, preferably thrombotic or thromboembolic disorders, and oedemas, and also ophthalmic disorders.Type: GrantFiled: July 5, 2016Date of Patent: September 24, 2019Assignee: BAYER PHARMA AKTIENGESELLSCHAFTInventors: Eloisa Jimenez Nunez, Jens Ackerstaff, Susanne Röhrig, Alexander Hillisch, Katharina Meier, Stefan Heitmeier, Adrian Tersteegen, Jan Stampfuß, Pascal Ellerbrock, Daniel Meibom, Dieter Lang
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Patent number: 10300062Abstract: The present application relates to novel bicyclically substituted uracil derivatives, to processes for preparation thereof, to the use thereof alone or in combinations for treatment and/or prophylaxis of diseases, and to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases.Type: GrantFiled: March 5, 2018Date of Patent: May 28, 2019Assignee: Bayer Pharma AktiengesellschaftInventors: Chantal Fürstner, Jens Ackerstaff, Alexander Straub, Heinrich Meier, Hanna Tinel, Katja Zimmermann, Adrian Tersteegen, Dmitry Zubov, Raimund Kast, Jens Schamberger, Martina Schäfer, Kirsten Börngen
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Patent number: 10167280Abstract: The invention relates to substituted oxopyridine derivatives and to processes for preparation thereof, and also to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases, especially of cardiovascular disorders, preferably thrombotic or thromboembolic disorders, and oedemas, and also ophthalmic disorders.Type: GrantFiled: September 22, 2015Date of Patent: January 1, 2019Assignee: BAYER PHARMA AKTIENGESELLSCHAFTInventors: Susanne Röhrig, Eloisa Jimenez Nunez, Karl-Heinz Schlemmer, Adrian Tersteegen, Henrik Teller, Alexander Hillisch, Stefan Heitmeier, Martina Victoria Schmidt, Jens Ackerstaff, Jan Stampfuß
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Publication number: 20180263981Abstract: The present application relates to novel substituted 5-fluoro-1H-pyrazolopyridines, to processes for their preparation, to their use alone or in combinations for the treatment and/or prophylaxis of diseases, and to their use for producing medicaments for the treatment and/or prophylaxis of diseases, in particular for the treatment and/or prophylaxis of cardiovascular disorders.Type: ApplicationFiled: May 16, 2018Publication date: September 20, 2018Applicant: ADVERIO PHARMA GMBHInventors: Markus FOLLMANN, Johannes-Peter STASCH, Gorden REDLICH, Jens ACKERSTAFF, Nils GRIEBENOW, Walter KROH, Andreas KNORR, Eva-Maria BECKER, Frank WUNDER, Volkhart Min-Jian LI, Elke HARTMANN, Joachim MITTENDORF, Karl-Heinz SCHLEMMER, Rolf JAUTELAT, Donald BIERER
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Publication number: 20180256576Abstract: The present application relates to novel bicyclically substituted uracil derivatives, to processes for preparation thereof, to the use thereof alone or in combinations for treatment and/or prophylaxis of diseases, and to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases.Type: ApplicationFiled: March 5, 2018Publication date: September 13, 2018Applicant: Bayer Pharma AktiengesellschaftInventors: Chantal FÜRSTNER, Jens ACKERSTAFF, Alexander STRAUB, Heinrich MEIER, Hanna TINEL, Katja ZIMMERMANN, Adrian TERSTEEGEN, Dmitry ZUBOV, Raimund KAST, Jens SCHAMBERGER, Martina SCHÄFER, Kirsten BÖRNGEN
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Publication number: 20180250280Abstract: The invention relates to substituted oxopyridine derivatives and to processes for preparation thereof, and also to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases, especially of cardiovascular disorders, preferably thrombotic or thromboembolic disorders, and oedemas, and also ophthalmic disorders.Type: ApplicationFiled: August 30, 2016Publication date: September 6, 2018Applicant: BAYER PHARMA AKTIENGESELLSCHAFTInventors: Eloisa JIMENEZ NUNEZ, Jens ACKERSTAFF, Pascal ELLERBROCK, Alexander HILLISCH, Katharina MEIER, Stefan HEITMEIER, Adrian TERSTEEGEN, Jan STAMPFUß
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Publication number: 20180194745Abstract: The invention relates to substituted oxopyridine derivatives and to processes for their preparation, and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular cardiovascular disorders, preferably thrombotic or thromboembolic disorders, and oedemas, and also ophthalmic disorders.Type: ApplicationFiled: July 5, 2016Publication date: July 12, 2018Inventors: Eloisa JIMENEZ NUNEZ, Jens ACKERSTAFF, Susanne RÖHRIG, Alexander HILLISCH, Katharina MEIER, Stefan HEITMEIER, Adrian TERSTEEGEN, Jan STAMPFUß, Pascal ELLERBROCK, Daniel MEIBOM, Dieter LANG
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Patent number: 9993476Abstract: The present application relates to novel substituted 5-fluoro-1H-pyrazolopyridines, to processes for their preparation, to their use alone or in combinations for the treatment and/or prophylaxis of diseases, and to their use for producing medicaments for the treatment and/or prophylaxis of diseases, in particular for the treatment and/or prophylaxis of cardiovascular disorders.Type: GrantFiled: November 10, 2016Date of Patent: June 12, 2018Assignee: ADVERIO PHARMA GMBHInventors: Markus Follmann, Johannes-Peter Stasch, Gorden Redlich, Jens Ackerstaff, Nils Griebenow, Walter Kroh, Andreas Knorr, Eva-Maria Becker, Frank Wunder, Volkhart Min-Jian Li, Elke Hartmann, Joachim Mittendorf, Karl-Heinz Schlemmer, Rolf Jautelat, Donald Bierer
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Publication number: 20180148418Abstract: The present invention relates to amido-substituted cyclohexane compounds of general formula (I), in which A, R4, R6, R7, R8, R9, R10 and R11 are as defined herein, to methods of preparing said compounds, to intermediate compounds useful for preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of neoplasms, as a sole agent or in combination with other active ingredient.Type: ApplicationFiled: May 2, 2016Publication date: May 31, 2018Applicant: Bayer Pharma AktiengesellschaftInventors: Knut EIS, Jens ACKERSTAFF, Sarah WAGNER, Philipp BUCHGRABER, Detlev SÜLZLE, Simon HOLTON, Eckhard BENDER, Volkhart LI, Ningshu LIU, Franziska SIEGEL, Philip LIENAU, Michaela BAIRLEIN, Franz VON NUSSBAUM, Simon Anthony HERBERT, Marcus KOPPITZ
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Patent number: 9949978Abstract: The present application relates to novel bicyclically substituted uracil derivatives, to processes for preparation thereof, to the use thereof alone or in combinations for treatment and/or prophylaxis of diseases, and to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases.Type: GrantFiled: October 7, 2016Date of Patent: April 24, 2018Assignee: Bayer Pharma AktiengesellschaftInventors: Chantal Fürstner, Jens Ackerstaff, Alexander Straub, Heinrich Meier, Hanna Tinel, Katja Zimmermann, Adrian Tersteegen, Dmitry Zubov, Raimund Kast, Jens Schamberger, Martina Schäfer, Kirsten Börngen
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Patent number: 9949977Abstract: The present application relates to novel bicyclically substituted uracil derivatives, to processes for preparation thereof, to the use thereof alone or in combinations for treatment and/or prophylaxis of diseases, and to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases.Type: GrantFiled: October 7, 2016Date of Patent: April 24, 2018Assignee: Bayer Pharma AktiengesellschaftInventors: Chantal Fürstner, Jens Ackerstaff, Alexander Straub, Heinrich Meier, Hanna Tinel, Katja Zimmermann, Adrian Tersteegen, Dmitry Zubov, Raimund Kast, Jens Schamberger, Martina Schäfer, Kirsten Börngen