Patents by Inventor Jens Cardinale

Jens Cardinale has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 18F - TAGGED INHIBITORS OF PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA) AND THEIR USE AS IMAGING AGENTS FOR PROSTATE CANCER
    Publication number: 20230295092
    Abstract: The present invention generally relates to the field of radiopharmaceuticals and their use in nuclear medicine as tracers and imaging agents for various disease states of prostate cancer.
    Type: Application
    Filed: March 17, 2023
    Publication date: September 21, 2023
    Inventors: Jens Cardinale, Martin Schaefer, Klaus Kopka, Matthias Eder, Ulrike Bauder-Wuest, Michael Eisenhut, Martina Benesova, Uwe Haberkorn, Frederik L. Giesel
  • Double-labeled probe for molecular imaging and use thereof
    Patent number: 11638765
    Abstract: The present invention relates to a compound of a pharmaceutically acceptable salt thereof of formula (I) wherein (A) is at least one motif specifically binding to cell membranes of neoplastic cells; (B) at least one chelator moiety of radiometals; (C) a dye moiety; x1 is a spacer or a chemical single bond covalently connecting (A) to the rest of the molecule; x2 is a spacer or a chemical single bond covalently connecting (C) to the rest of the molecule. The invention further relates to compositions comprising said compounds as well as a method for detecting neoplastic cells in a sample in vitro with the aid of the compounds or composition.
    Type: Grant
    Filed: November 20, 2018
    Date of Patent: May 2, 2023
    Assignees: Deutsches Krebsforschungszentrum, Ruprecht-Karls -Uni versitaet Heidelberg
    Inventors: Matthias Eder, Klaus Kopka, Martin Schaefer, Ulrike Bauder-Wuest, Uwe Haberkorn, Ann-Christin Eder, Jens Cardinale, Martina Benesova
  • 18F - TAGGED INHIBITORS OF PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA) AND THEIR USE AS IMAGING AGENTS FOR PROSTATE CANCER
    Publication number: 20210053922
    Abstract: The present invention generally relates to the field of radiopharmaceuticals and their use in nuclear medicine as tracers and imaging agents for various disease states of prostate cancer.
    Type: Application
    Filed: October 23, 2020
    Publication date: February 25, 2021
    Inventors: Jens CARDINALE, Martin SCHAEFER, Klaus KOPKA, Matthias EDER, Ulrike BAUDER-WUEST, Michael EISENHUT, Martina BENESOVA, Uwe HABERKORN, Frederik L. GIESEL
  • A DOUBLE-LABELED PROBE FOR MOLECULAR IMAGING AND USE THEREOF
    Publication number: 20200353109
    Abstract: The present invention relates to a compound of a pharmaceutically acceptable salt thereof of formula (I) wherein (A) is at least one motif specifically binding to cell membranes of neoplastic cells; (B) at least one chelator moiety of radiometals; (C) a dye moiety; x1 is a spacer or a chemical single bond covalently connecting (A) to the rest of the molecule; x2 is a spacer or a chemical single bond covalently connecting (C) to the rest of the molecule. The invention further relates to compositions comprising said compounds as well as a method for detecting neoplastic cells in a sample in vitro with the aid of the compounds or composition.
    Type: Application
    Filed: November 20, 2018
    Publication date: November 12, 2020
    Inventors: Matthias EDER, Klaus KOPKA, Martin SCHAEFER, Ulrike BAUDER-WUEST, Uwe HABERKORN, Ann-Christin EDER, Jens CARDINALE, Martina BENESOVA
  • 18F—tagged inhibitors of prostate specific membrane antigen (PSMA) and their use as imaging agents for prostate cancer
    Patent number: 10815200
    Abstract: The present invention generally relates to the field of radiopharmaceuticals and their use in nuclear medicine as tracers and imaging agents for various disease states of prostate cancer.
    Type: Grant
    Filed: March 8, 2018
    Date of Patent: October 27, 2020
    Assignees: DEUTSCHES KREBSFORSCHUNGSZENTRUM, RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG
    Inventors: Jens Cardinale, Martin Schaefer, Klaus Kopka, Matthias Eder, Ulrike Bauder-Wuest, Michael Eisenhut, Martina Benesova, Uwe Haberkorn, Frederik L. Giesel
  • 18F - TAGGED INHIBITORS OF PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA) AND THEIR USE AS IMAGING AGENTS FOR PROSTATE CANCER
    Publication number: 20180194729
    Abstract: The present invention generally relates to the field of radiopharmaceuticals and their use in nuclear medicine as tracers and imaging agents for various disease states of prostate cancer.
    Type: Application
    Filed: March 8, 2018
    Publication date: July 12, 2018
    Inventors: Jens CARDINALE, Martin SCHAEFER, Klaus KOPKA, Matthias EDER, Ulrike BAUDER-WUEST, Michael EISENHUT, Martina BENESOVA, Uwe HABERKORN, Frederik L. GIESEL
  • 18F-tagged inhibitors of prostate specific membrane antigen (PSMA), their use as imaging agents and pharmaceutical agents for the treatment of prostate cancer
    Patent number: 10016519
    Abstract: The present invention generally relates to the field of radiopharmaceuticals and their use in nuclear medicine as tracers, imaging agents and for the treatment of various disease states of prostate cancer.
    Type: Grant
    Filed: March 20, 2017
    Date of Patent: July 10, 2018
    Assignees: DEUTSCHES KREBSFORSCHUNGSZENTRIUM, RUPRECHT-KARLS-UNIVERSITÄT HEIDELBERG
    Inventors: Klaus Kopka, Martina Benesova, Jens Cardinale, Matthias Eder, Martin Schäfer, Ulrike Bauder-Wüst, Uwe Haberkorn, Michael Eisenhut
  • 18F-TAGGED INHIBITORS OF PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA), THEIR USE AS IMAGING AGENTS AND PHARMACEUTICAL AGENTS FOR THE TREATMENT OF PROSTATE CANCER
    Publication number: 20170246327
    Abstract: The present invention generally relates to the field of radiopharmaceuticals and their use in nuclear medicine as tracers, imaging agents and for the treatment of various disease states of prostate cancer.
    Type: Application
    Filed: March 20, 2017
    Publication date: August 31, 2017
    Inventors: Klaus KOPKA, Martina Benesova, Jens Cardinale, Matthias Eder, Martin SCHÄFER, Ulrike BAUDER-WÜST, Uwe Haberkorn, Michael Eisenhut