Abstract: A building including at least one pressure lock configured to facilitate an exchange of materials and persons between the building and a clean area in the building; a ventilation arrangement configured to feed supply air from the building into a top of the clean area; and an extraction arrangement configured to extract exhaust air from a bottom of the clean area into the building so that the clean area has a positive pressure relative to the building, wherein the clean area includes a floor and a shell that encloses the clean area above the floor pressure tight, wherein the building includes an outer enclosure that protects the clean area against weather conditions outside the building, wherein the shell is flexible at least in a major portion of a surface area of the shell and the positive pressure moves the shell into a shape of the clean area.

Abstract: The present invention relates to a pulsatile positive-displacement pump with a flexible positive-displacement diaphragm which is operated pneumatically and by whose movement the blood is aspirated and displaced. A mechanical switching device in the interior of a drive unit ensures an autonomous operation of the blood pump, wherein no electricity or electronics system is needed.

Abstract: A building including at least one pressure lock configured to facilitate an exchange of materials and persons between the building and a clean area in the building; a ventilation arrangement configured to feed supply air from the building into a top of the clean area; and an extraction arrangement configured to extract exhaust air from a bottom of the clean area into the building so that the clean area has a positive pressure relative to the building, wherein the clean area includes a floor and a shell that encloses the clean area above the floor pressure tight, wherein the building includes an outer enclosure that protects the clean area against weather conditions outside the building, wherein the shell is flexible at least in a major portion of a surface area of the shell and the positive pressure moves the shell into a shape of the clean area.

Abstract: Thermal pads for incorporation into systems and compression garments may be used for various medical or other purposes. The pads include thermal fluid channels and the ability to flex and elastically stretch in multiple directions for conformance to the individual user. Cooling systems include recirculation of the thermal fluid for temperature control purposes. Methods include hot and cold contrast type therapy for a variety of purposes.

Abstract: Thermal pads (50) for incorporation into systems (10) and compression garments (54) may be used for various medical or other purposes. The pads (50) include thermal fluid channels and the ability to flex and elastically stretch in multiple directions for conformance to the individual user. Cooling systems (10) include recirculation of the thermal fluid for temperature control purposes. Methods include hot and cold contrast type therapy for a variety of purposes.

Abstract: A ventricular-assist-device valve includes two flaps hinged to a peripheral wall by means of a couple of flexible struts. As each flap opens and closes during each cycle of operation, the struts flex and open passages for flow around them, around the flaps, and between the struts and the flaps, so as to prevent the formation of dead zones that contribute to the accumulation and deterioration of blood cells that produce clotting. The struts are tensioned so as to exert a pressure against the flow of the blood stream when the flaps are open. This tension creates a pressure differential between the underside and the peripheral regions of the flaps that forces blood flow around the hinges and washes out stagnant cells. As a result, clotting is materially reduced.

Abstract: A cannula for use as for example on the inflow end of an implantable intravascular heart pump. The stiffness of the cannula is differentiated along its length, wherein its proximal end is stiffer than its distal end, while a substantially constant wall thickness is maintained along its entire length. Attached to the flexible distal end, is a rigid tip component having inlet ports and an interior surface profile that minimizes the risk of hemolysis and thrombogenisis.