Abstract: The present invention relates to methods and pharmaceutical compositions for prevention or treatment of a metabolic disease in a human patient in need thereof, comprising administration of a therapeutically effective amount, or a prophylactically effective amount, of a combination of sacubitril and valsartan in a 1:1 molar ratio to said patient.

Abstract: A lighting strip for an aircraft interior is provided. The lighting strip has a connection for a network voltage, a rectifier for rectifying the network voltage into a power supply voltage, and a circuit board extending along a longitudinal extension of the lighting strip. Multiple LEDs are arranged on the circuit board and powered by the power supply voltage. A controllable current sink arrangement, having multiple individual sink devices connected electrically in parallel with one another, is provided for converting electrical energy transported via the connection into heat. The individual sink devices are distributed on the circuit board along the longitudinal extension of the circuit board. The sink devices are controlled by a control apparatus independently from the operative conditions of the LEDs to provide a homogenously distributed thermal profile of the lighting strip.

Abstract: An electrical supply apparatus is provided. The apparatus has an input for connecting the electrical supply apparatus to a power supply system, an output for connecting the electrical supply apparatus to a load, a rectifier for rectifying the input voltage into a rectified input voltage, and a PFC module for smoothing the rectified input voltage. The PFC module also has an active power factor correction device for shaping a time-dependent supply current, such that a time-dependent input current into the PFC module is matched to a time-dependent current waveform signal. A control module is provided for generating the current waveform signal. The control module generates the current waveform signal during the operation of the electrical supply apparatus independently of the input voltage and temporally synchronizes the current waveform signal with the input voltage or a derivative of the input voltage.

Abstract: An LED lighting apparatus is provided. The apparatus has an LED luminous unit having multiple plurality LEDs and a switching arrangement. The LED luminous unit has different forward voltages in different switching states. The apparatus also has a control device for driving the LED luminous unit and a current sink device in a normal operating mode, in which the forward voltage and the LED current of the LED luminous unit are adapted to an instantaneous value of a supply voltage. An energy storage module of the apparatus provides a storage voltage and supplies the storage voltage to the LED luminous unit. The control device drives the LED luminous unit and the current sink device in a storage operating mode, such that the forward voltage and the LED current of the LED luminous unit are adapted to an instantaneous value of the storage voltage.

Abstract: In comparison with thermal light sources, LED lighting has the advantage that it is very small and at the same time commercially available in different colors, so that colored lighting can be produced inexpensively and at the same time in a manner that saves installation space. It is an object of the present invention to equip an LED lighting apparatus with a color mixing functionality that is distinguished by high efficiency and at the same time a small number of components.

Abstract: An LED lighting device for supplying a main voltage by an AC power supply is provided. The device has a rectifier for producing a rectified AC voltage from the main voltage, an LED light unit having multiple of LEDs and a circuit arrangement, and a control device for controlling the circuit arrangement. The circuit arrangement switches the LEDs to different circuit states, in which the LED light unit has different forward voltages. The control device controls the circuit arrangement, in such a way that the forward voltage of the LED light unit is adjusted to the voltage profile of the rectified AC voltage. The device also has a modelling device for modelling a modelled voltage profile. The control device controls the circuit states based on the modelled voltage profile. The modelled voltage profile is modelled based on measured variables for describing the real voltage profile of the main voltage.

Abstract: An LED lighting device for AC voltage supply is provided. The device has LEDs that form a whole chain. The LEDs are divided into LED part groups. The device also has multiple serial switching means, multiple shorting links and a control means. The control means is configured to control the shorting links and the serial switching means, to place the whole chain in at least two switch states. The switch states differ in the through voltage of the whole chain.

Abstract: An LED lighting apparatus 1 for an AC voltage supply 2 comprising a rectifier device 5, comprising at least one LED luminous unit 7, having a plurality of LEDs 10a, b, c, d and a switching arrangement 9, wherein the switching arrangement 9 is designed for interconnecting the LEDs 10a, b, c, d into different switching states I, II, III, wherein the LED luminous unit 7 has different forward voltages in the different switching states I, II, III, comprising a current sink device 6 and comprising a control device 8 for driving the LED luminous unit 7 and the current sink device 6 in a normal operating mode, wherein the forward voltage of the LED luminous unit 7 and the LED current through the LED luminous unit 7 are adapted to an instantaneous value of the supply voltage 11 and/or of the AC voltage, and comprising an energy storage module 13, wherein the energy storage module 13 provides a storage voltage 18 and is designed for supplying the at least one LED luminous unit 7, and wherein the control device 8 is des

Abstract: The present invention is directed to an LED lighting device for an AC power supply which emits a particularly uniform light.

Abstract: In comparison with thermal light sources, LED lighting has the advantage that it is very small and at the same time commercially available in different colours, so that coloured lighting can be produced inexpensively and at the same time in a manner that saves installation space. It is an object of the present invention to equip an LED lighting apparatus with a colour mixing functionality that is distinguished by high efficiency and at the same time a small number of components.

Abstract: The present invention relates to a lighting strip for an aircraft interior that is particularly easy to integrate and/or is characterized by particularly good operating properties.

Abstract: The object of the present invention is to provide an electrical supply apparatus which keeps the loading of the supply system low. What is proposed for this purpose is an electrical supply apparatus, in particular a power supply unit comprising a power factor correction device 7, wherein the power factor correction device generates a current waveform signal from a predefined current waveform pattern half-cycle.

Abstract: It is the task of the present invention to provide an LED lighting device that is adapted for an AC voltage supply. Suggested for that is an LED lighting device 1 for an AC voltage supply 2, with several LEDs that form a whole chain 9, whereby the LEDs are divided into LED part groups 11 a, b, c, d, x, y, whereby a supply voltage with changing amplitude is present in the LED lighting device 1, and with several serial switching means 12a, b, c, d, x, y, and with several shorting links 16a, b, and with a control means 10, whereby the control means 10 is designed for controlling the shorting links 16a, b, and the serial switching means 12a, b, c, d, x, y in order to place the whole chain 9 in at least two switch states 1,11, whereby the at least two switch states 1,11 differ in the through voltage of the whole chain 9.

Abstract: A method for monitoring and controlling a plurality of series-connected capacitance, wherein at least during the discharge of the capacitances, there is determined a voltage of every capacitance, and in the instance of a drop-off of a voltage of one of the capacitances below a first threshold voltage of this capacitance, the capacitance is bridged over to at least the end of the discharge. Also provided are devices for determining every voltage of every capacitance, devices for symmetrizing voltages among the capacitances, and devices for the deactivation of at least one of the capacitances.

Abstract: A method for monitoring and controlling a plurality of series-connected capacitance, wherein at least during the discharge of the capacitances, there is determined a voltage of every capacitance, and in the instance of a drop-off of a voltage of one of the capacitances below a first threshold voltage of this capacitance, the capacitance is bridged over to at least the end of the discharge. Also provided are devices for determining every voltage of every capacitance, devices for symmetrizing voltages among the capacitances, and devices for the deactivation of at least one of the capacitances.