Abstract: The invention relates to a mutant polypeptide having creatine amidinohydrolase activity, where the polypeptide both retains thermostable activity in the presence of reagents that modify thiol groups. The invention further relates to methods for producing the mutant polypeptide; and to a sensor comprising the mutant polypeptide for use in the measurement of creatinine in samples of physiological fluids. Additionally, the invention teaches how to use the mutant polypeptide to enhance the life-time of a creatinine sensor, and a method for producing the sensor.

Abstract: The invention relates to a mutant polypeptide having creatine amidinohydrolase activity, where the polypeptide both retains thermostable activity in the presence of reagents that modify thiol groups. The invention further relates to methods for producing the mutant polypeptide; and to a sensor comprising the mutant polypeptide for use in the measurement of creatinine in samples of physiological fluids. Additionally, the invention teaches how to use the mutant polypeptide to enhance the life-time of a creatinine sensor, and a method for producing the sensor.

Abstract: A radiation emitting element comprising a radiation transmissive element having a first refractive index, a first surface, a second, opposite surface, a radiation emitter adapted to emit radiation of a predetermined wavelength into the radiation transmissive element, and a plurality of radiation controlling elements, wherein each radiation controlling element comprises: a first liquid having a second refractive index, a second fluid having a third refractive index being lower than the second refractive index, the second refractive index being closer to the first refractive index than the third refractive index, means for altering a shape of the first liquid between two modes wherein: in a first mode, the first liquid being in contact with the first surface at a first surface part, and an interface between the first liquid and the second fluid, at the first surface part, is not parallel to the first surface part and in a second mode, a surface of the second fluid, at the first surface part, is at least su

Abstract: The invention concerns a semiconductor based light source comprising a back part, a front side and at least one semiconductor chip having an emitting surface, at least one reflective optical element being arranged below said at least one semiconductor chip, a material with low refractive index being disposed on a side of said reflective optical element facing said front side, wherein said semiconductor based light source comprises on said front side a compound material with high refractive index having at least one diffractive optical element embedded therein, such as to direct light incident on said diffractive optical element towards preferred directions.

Abstract: A method is provided for stabilizing a creatinine sensor comprising creatininase as a bioactive molecule. The creatininase is stabilised by exposing it to a sufficient amount of a divalent manganese ion. This result may be obtained by exposing the sensor to a solution comprising the divalent manganese ion or by introducing a composition within the sensor providing sustained release of the divalent manganese ion.

Abstract: A method and a system for determining the position of a radiation emitter, which radiation emitter may be an actively radiation emitting stylus, pen, pointer, or the like or may be a passive, radiation scattering/reflecting/diffusing element, such as a pen, pointer, or a finger of an operator. The radiation from the emitter is reflected from that position toward the detector by a reflecting element providing multiple intensity spots on the detector providing sufficient information for determining the position. From the output of the detector, the position of the radiation emitter is determined.

Abstract: A system and a method for using a single 2-D-radiation detector for simultaneously detecting radiation from a plurality of independent applications and for outputting a signal from which information relating to each application may be derived. The radiation from each application is provided to individuals parts of the sensor.

Abstract: A method is provided for stabilising a creatinine sensor comprising creatininase as a bioactive molecule. The creatininase is stabilised by exposing it to a sufficient amount of a divalent manganese ion. This result may be obtained by exposing the sensor to a solution comprising the divalent manganese ion or by introducing a composition within the sensor providing sustained release of the divalent manganese ion.

Abstract: The present invention relates to the art of dispensing medicine to a user of medicine, and relates in particular to a medicine dispenser for dispensing doses of medicaments, a loader for loading doses of medicine into the medicine dispenser, a medicine distribution box, a packing device for packing medicaments in predefined doses, a Central Medication Database and a system comprising all these objects. Furthermore, the invention relates to a method of dispensing doses of medicaments, a method of loading medicine into a medicine dispenser, a method of distributing medicine, a method of packing medicaments in predefined doses, a method of carrying out various aspects related to dispensing medicine as well as a method integrating all the above mentioned methods.

Abstract: The invention relates to a method of reducing emission of ammonia from animal manure and a plant for the method and a used of such a plant. The method comprises adding to the manure of both an acid compound such as sulphuric acid, H2S04, and of oxygen, O2. The acid compound results in the pH value dropping to below 7.0 whereby the emission of ammonia is substantially limited. The oxygen results in a very high activity of bacteria transforming organic nitrogen compounds to in-organic compounds that are possible for plants to assimilate when manure is spread in fields. Surprisingly, it has also should to be the case that the oxygen added, and thus the enhancing of the activity of the bacteria. results in a reduction of the amount of acid compound needed to he added and results in reducing, almost eliminating, the risk of hydrogen sulphide, H2S, being formed.

Abstract: The present invention relates to a polynucleotide in isolated form, which polynucleotide codes for a protein with the activity of the enzyme L-galactono-&ggr;-lactone dehydrogenase, which polynucleotide comprises at least the L-galactono-&ggr;-lactone dehydrogenase activity-determining parts of the coding part of the sequence or a sequence derived therefrom on the basis of the degeneration of the genetic code. The invention further relates to the use of the polynucleotide in the production of transgenic plants, plant cells, or other eukaryotic cells.

Abstract: The present invention relates to a polynucleotide in isolated form, which polynucleotide codes for a protein with the activity of the enzyme L-galactono-&ggr;-lactone dehydrogenase, which polynucleotide comprises at least the L-galactono-&ggr;-lactone dehydrogenase activity-determining parts of the coding part of the nucleotide sequence or a sequence derived therefrom on the basis of the degeneration of the genetic code. The invention further relates to the use of the polynucleotide in the production of transgenic plants, plant cells, or other eukaryotic cells.