Abstract: Systems and techniques are described for processing image data using a residual model that can be configured with an adjustable number of sampling steps. For example, a process can include obtaining a latent representation of an image and processing, using a decoder of a machine learning model, the latent representation of the image to generate an initial reconstructed image. The process can further include processing, using the residual model, the initial reconstructed image and noise data to predict a plurality of predictions of a residual over a number of sampling steps. The residual represents a difference between the image and the initial reconstructed image. The process can include obtaining, from the plurality of predictions of the residual, a final residual representing the difference between the image and the initial reconstructed image. The process can further include combining the initial reconstructed image and the residual to generate a final reconstructed image.

Abstract: The present invention describes 2-methyl-quinazoline compounds of general formula (I), methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds, and the use of said compounds for manufacturing pharmaceutical compositions. The 2-methyl substituted quinazoline compounds of general formula (I) effectively and selectively inhibit the Ras-Sos interaction without significantly targeting the EGFR receptor. They are therefore useful for the treatment or prophylaxis of diseases, in particular of hyperproliferative disorders, such as cancer as a sole agent or in combination with other active ingredients.

Abstract: An optical system can include an optical arrangement supported by an optical chassis. A flexure arrangement can support the optical chassis relative to a separate structure to maintain a calibrated distance between optical components of the optical arrangement.

Abstract: The present disclosure provides a computer implemented method for facilitating a teaching surgeon to teach or assist a learning surgeon in minimally invasive interventions using a surgical instrument including displaying endoscopic images of an intervention site in real time on a display device, said endoscopic images being captured using a camera associated with an endoscopic instrument, and tracking a movement of one or both hands of said teaching surgeon and/or a device held by said teaching surgeon, using a real-time tracking apparatus, wherein said real-time tracking apparatus comprises a tracking system and a computing device, wherein said tracking of said movement comprises recording a sequence of tracking information of one or both hands of said teaching surgeon and/or the device held by said teaching surgeon.

Abstract: The disclosure relates to an electric power steering system having a rack for steering wheels of a vehicle and having a pinion shaft. The pinion shaft meshes with a row of teeth of the rack in an assembled state. The rack has an assembly portion for an initial assembly of the pinion shaft, with one end of the row of teeth transitioning into the assembly portion. On the one hand, to facilitate initial assembly for establishing a connection between the pinion shaft and the row of teeth of the rack and, on the other hand, to prevent the connection between the pinion shaft and the row of teeth of the rack from breaking during repair measures carried out after the initial assembly, the electric power steering system is arranged such that first teeth of the row of teeth each have a first tooth height and the assembly portion has second teeth for interacting with the pinion shaft, the second teeth each having a second tooth height that is less than the first tooth height.

Abstract: There are disclosed certain novel compounds (including pharmaceutically acceptable salts thereof), that inhibit phosphatidylinositol 3-kinase gamma (PI3K?) and phosphatidylinositol 3-kinase gamma (PI3K?) activity, to their utility in treating and/or preventing clinical conditions including respiratory diseases, such as asthma and chronic obstructive pulmonary disease (COPD), to their use in therapy, to pharmaceutical compositions containing them and to processes for preparing such compounds.

Abstract: Disclosed herein is the compound (S)-2-(1-cyclopropylethyl)-5-(4-methyl-2-((6-(2-oxopyrrolidin-1-yl)pyridin-2-yl)amino)thiazol-5-yl)-7-(methylsulfonyl)isoindolin-1-one of the following structure: and/or pharmaceutically acceptable salts and/or pharmaceutical compositions thereof, which inhibit phosphatidylinositol 3-kinase (PI3K) activity.

Abstract: There are disclosed certain novel compounds (including pharmaceutically acceptable salts thereof), that inhibit phosphatidylinositol 3-kinase gamma (PI3K?) activity, to their utility in treating and/or preventing clinical conditions including respiratory diseases, such as asthma and chronic obstructive pulmonary disease (COPD), to their use in therapy, to pharmaceutical compositions containing them and to processes for preparing such compounds.

Abstract: There are disclosed certain novel compounds (including pharmaceutically acceptable salts thereof), that inhibit phosphatidylinositol 3-kinase gamma (PI3K?) activity, to their utility in treating and/or preventing clinical conditions including respiratory diseases, such as asthma and chronic obstructive pulmonary disease (COPD), to their use in therapy, to pharmaceutical compositions containing them and to processes for preparing such compounds.

Abstract: There are disclosed certain novel compounds (including pharmaceutically acceptable salts thereof), that inhibit phosphatidylinositol 3-kinase gamma (PI3K?) and phosphatidylinositol 3-kinase gamma (PI3K?) activity, to their utility in treating and/or preventing clinical conditions including respiratory diseases, such as asthma and chronic obstructive pulmonary disease (COPD), to their use in therapy, to pharmaceutical compositions containing them and to processes for preparing such compounds.

Abstract: There are disclosed certain novel compounds (including pharmaceutically acceptable salts thereof), that inhibit phosphatidylinositol 3-kinase gamma (P13K?) activity, to their utility in treating and/or preventing clinical conditions including respiratory diseases, such as asthma and chronic obstructive pulmonary disease (COPD), to their use in therapy, to pharmaceutical compositions containing them and to processes for preparing such compounds.

Abstract: A device for projecting a time variable optical pattern onto an object that is to be measured in three dimensions, the device comprising a frame for an optical pattern; a light source with optional illumination optics; and imaging optics, wherein the optical pattern is on slide that is attached to a movement mechanism that moves the optical pattern relative to the optional illumination optics and/or relative to the imaging optics, wherein the movement mechanism causes a movement of the optical pattern in a slide plane that is oriented orthogonal to an optical axis of the imaging optics.

Abstract: A coaxial cable connector for attachment to an end of a coaxial cable is disclosed. The coaxial cable connector includes a rotatable body segment having a body wall with an outer surface and an inner surface defining a width of the body wall. The body wall has a radial dimension which varies along a perimeter of the rotatable body segment. The inner surface defines a longitudinal opening extending between a forward end of the rotatable body segment and a rearward end of the rotatable body segment. A post positions proximal the forward end of the rotatable body segment. The post has a first end and a second end with a bore extending therebetween. The post is rotationally stationary with respect to the rotatable body segment. A coupling member positions proximal to the first end of the post. The rotatable body segment is rotated to close the coaxial cable connector.

Abstract: A coaxial cable connector for attachment to an end of a coaxial cable is disclosed. The coaxial cable connector has a body having a forward end and a rearward end. An internal surface extends between the forward end and the rearward end defining a longitudinal opening and with a cable receiving area proximal the rearward end and a jacket stop proximal the forward end. A post is positioned in the body proximal the forward end and has a first end and a second end with a bore extending therebetween. An insulator is movably disposed in the bore of the post and has a through-passage and a movement limiter. A gripping member is disposed within the longitudinal opening of the body proximal the rearward end and provides a gripping action as the gripping member axially moves toward the forward end of the body.

Abstract: A coaxial cable connector for attachment to an end of a coaxial cable is disclosed. The coaxial cable connector has a body having a forward end and a rearward end. An internal surface extends between the forward end and the rearward end defining a longitudinal opening and with a cable receiving area proximal the rearward end and a jacket stop proximal the forward end. A post is positioned in the body proximal the forward end and has a first end and a second end with a bore extending therebetween. An insulator is movably disposed in the bore of the post and has a through-passage, and a movement limiter. A gripping member is disposed within the longitudinal opening of the body proximal the rearward end and provides a gripping action as the gripping member axially moves toward the forward end of the body.

Abstract: A device for projecting a time variable optical pattern onto an object that is to be measured in three dimensions, the device comprising a frame for an optical pattern; a light source with optional illumination optics; and imaging optics, wherein the optical pattern is on slide that is attached to a movement mechanism that moves the optical pattern relative to the optional illumination optics and/or relative to the imaging optics, wherein the movement mechanism causes a movement of the optical pattern in a slide plane that is oriented orthogonal to an optical axis of the imaging optics.

Abstract: A post-less, self-gripping coaxial cable connector for tool-less attachment to an end of a coaxial cable is disclosed. The coaxial cable connector has a body having a forward end and a rearward end and a longitudinal opening. A retainer positioned in the body has a forward section, a rearward section, and a bore. A ring is movably disposed in the retainer. A gripping member having at least one spring finger is friction fit to the body and is radially inwardly biased in a predisposed orientation. The ring has a pusher feature configured to axially move the ring upon force being applied to the pusher feature by a coaxial cable received by the body causing the gripping member to engage the jacket of the coaxial cable when the coaxial cable is installed in the coaxial cable connector.

Abstract: A coaxial cable connector for attachment to an end of a coaxial cable is disclosed. The coaxial cable connector has a body having a forward end and a rearward end. An internal surface extends between the forward end and the rearward end defining a longitudinal opening and with a cable receiving area proximal the rearward end and a jacket stop proximal the forward end. A post is positioned in the body proximal the forward end and has a first end and a second end with a bore extending therebetween. An insulator is movably disposed in the bore of the post and has a through-passage and a movement limiter. A gripping member is disposed within the longitudinal opening of the body proximal the rearward end and provides a gripping action as the gripping member axially moves toward the forward end of the body.

Abstract: A coaxial cable connector for attachment to an end of a coaxial cable is disclosed. The coaxial cable connector includes a rotatable body segment having a body wall with an outer surface and an inner surface defining a width of the body wall. The body wall has a radial dimension which varies along a perimeter of the rotatable body segment. The inner surface defines a longitudinal opening extending between a forward end of the rotatable body segment and a rearward end of the rotatable body segment. A post positions proximal the forward end of the rotatable body segment. The post has a first end and a second end with a bore extending therebetween. The post is rotationally stationary with respect to the rotatable body segment. A coupling member positions proximal to the first end of the post. The rotatable body segment is rotated to close the coaxial cable connector.