Abstract: The present invention relates to: recombinant microorganisms expressing lipoxygenase; and recombinant microorganisms co-expressing lipoxygenase and Chlorella-derived decarboxylase. It was confirmed that when using lipoxygenase-based recombinant microorganisms according to the present invention as whole-cell biocatalysts, hydroxy fatty acids can be produced from unsaturated fatty acids. In addition, it was confirmed that when using the recombinant microorganisms co-expressing lipoxygenase and Chlorella-derived decarboxylase as whole-cell biocatalysts, secondary fatty alcohols can be produced from unsaturated fatty acids. Thus, the recombinant microorganisms constructed in the present invention can be used in various ways in the field of hydroxy fatty acid and secondary fatty alcohol production.

Abstract: Disclosed are novel compounds of Chemical Formula 1, optical isomers of the compounds, and pharmaceutically acceptable salts of the compounds or the optical isomers. The compounds, isomers, and salts exhibit excellent activity as GLP-1 receptor agonists. In particular, they, as GLP-1 receptor agonists, exhibit excellent glucose tolerance, thus having a great potential to be used as therapeutic agents for metabolic diseases. Moreover, they exhibit excellent pharmacological safety for cardiovascular systems.

Abstract: The present invention relates to an eye movement measurement method including the steps of: (a) presenting standardized nystagmus test items and receiving am image of an eye in accordance with the standardized nystagmus test items; (b) recognizing a pupil and an iris from the image of the eye; (c) calculating amounts of horizontal and vertical changes of the pupil and an amount of torsional movement of the iris; (d) determining change values and orientations for three axis directions of the eye on the basis of the amounts of the horizontal and vertical changes of the pupil and the amount of the torsional movement of the iris; and (e) generating a diagnosis result for vertigo through deep learning modeling on the basis of the change values and orientations of the three axis directions of the eye.

Abstract: The present invention relates to an eye movement measurement method including the steps of: (a) presenting standardized nystagmus test items and receiving am image of an eye in accordance with the standardized nystagmus test items; (b) recognizing a pupil and an iris from the image of the eye; (c) calculating amounts of horizontal and vertical changes of the pupil and an amount of torsional movement of the iris; (d) determining change values and orientations for three axis directions of the eye on the basis of the amounts of the horizontal and vertical changes of the pupil and the amount of the torsional movement of the iris; and (e) generating a diagnosis result for vertigo through deep learning modeling on the basis of the change values and orientations of the three axis directions of the eye.