Abstract: The present invention relates to a method for producing marine algae-derived agarotriose, and a use thereof as a prebiotic. More specifically, the present invention investigates the characteristics of agarotriose as a prebiotic which is selectively metabolized by probiotic microorganisms, thereby enabling agarotriose to be used as an anti-cancer or anti-inflammatory agent in the fields of food and pharmaceuticals, and enabling agarotriose to be obtained at high yield through efficient purification with minimal loss after enzymatic hydrolysis of a red algae-derived polysaccharide without pre-treatment.

Abstract: An organic electroluminescence device of an embodiment may include a first electrode, a hole transport region disposed on the first electrode, an emission layer disposed on the hole transport region, an electron transport region disposed on the emission layer, and a second electrode disposed on the electron transport region. The electron transport region may include a first compound represented by Formula 1, thereby improving the moving speed of electrons. Accordingly, the organic electroluminescence device of an embodiment may show decreased driving voltage and improved efficiency.

Abstract: A plating steel sheet for hot press forming includes: a base steel sheet; an Al—Zn-based plating layer formed on at least one surface of the base steel sheet; and an Fe—Al-based surface alloy layer formed between the base steel sheet and the Al—Zn-based plating layer, wherein the Al—Zn-based plating layer can include 10-30 wt % of Zn, 1 wt % or less of Fe, and the balance of Al and impurities.

Abstract: The present invention relates to a mini-brain structure and a construction method therefor and, more specifically, to a mini-brain and a construction method therefor, wherein induced pluripotent stem cells can be used to prepare brain organoids for different brain regions accounting for the cerebrum, the mesencephalon, the cerebellum, the thalamus, and the like and the organoids are combined into single structures, thereby making it possible to further effectively implement actual brain functions and wherein brain organoids for different brain regions can be selectively combined into single structures according to purposes, thereby achieving the aim of using brain organoids and enhancing convenience and economical benefit.

Abstract: The present invention relates to a GRP78-derived peptide for screening highly efficient stem cells and the use thereof, and more particularly, to screening highly efficient stem cells using, as a marker, a GRP78-derived peptide capable of binding to the binding domain of GRP78 protein on the cell surface. According to the present invention, the GRP78-derived peptide comprising only a specific amino acid sequence capable of recognizing highly efficient stem cells, among the amino acid sequence of GRP78, makes it possible to screen only non-senescent young stem cells. In addition, when stem cells are treated with the GRP78-derived peptide or the GRP78-derived peptide is introduced into stem cells, the efficiency of the stem cells can be increased. Thus, the GRP78-derived peptide is useful for the production of stem cell therapy products having excellent efficacy.

Abstract: A semiconductor package is provided. The semiconductor package includes a first semiconductor substrate, a first semiconductor element layer on an upper surface of the first semiconductor substrate, a first wiring structure on the first semiconductor element layer, a first connecting pad connected to the first wiring structure, a first test pad connected to the first wiring structure, a first front side bonding pad connected to the first connecting pad and including copper (Cu), and a second front side bonding pad connected to the first front side bonding pad and including copper (Cu) which has a nanotwin crystal structure different from a crystal structure of copper (Cu) included in the first front side bonding pad, wherein a width of the first front side bonding pad in the horizontal direction is different from a width of the second front side bonding pad in the horizontal direction.

Abstract: The present invention relates to: an antibody targeting a mutation of KRAS, which is an intracellular tumor-inducing protein, or a fusion protein in which a cancer-cell-penetrating peptide is connected, by means of a gene expression method or a chemical bonding method, to a single strand variable fragment of the antibody; and a tumor treatment use thereof. The fusion protein thus produced has the benefit of maximizing the anti-tumor or anti-cancer effect of the antibody targeting an intracellular tumor-inducing protein or a tumor-inducing mutant protein, or the single strand variable fragment of the antibody, by effectively invading a tumor cell.

Abstract: The present disclosure provides ex vivo armed T cell (EAT) compositions that comprise multi-specific (e.g., bispecific) antibodies that bind to CDS and at least one additional target antigen (e.g., antigen that is expressed by tumor cells and/or a DOTA label). The EAT compositions of the present technology are useful for adoptive immunotherapy in a subject in need thereof.

Abstract: The present invention relates to a BMP-9 variant and a derivative thereof. The variant stimulates endothelial cell-specific signaling, but does not stimulate ectopic ossification-related signaling, as compared to wild-type BMP-9, and thus has the effects of enhancing therapeutic effects on various diseases, including tumors, cardiovascular disease, fibrotic diseases, inflammatory diseases, metabolic diseases, and autoimmune diseases, and reducing side effects.

Abstract: Provided is a capsule endoscope. The capsule endoscope includes: an imaging device configured to perform imaging on a digestive tract in vivo to generate an image; an artificial neural network configured to determine whether there is a lesion area in the image; and a transmitter configured to transmit the image based on a determination result of the artificial neural network.

Abstract: The present disclosure relates to a display device comprising a substrate including a plurality of sub-pixels, a thin film transistor and a light emitting element on the substrate, an encapsulation layer on the substrate and covering the light emitting element, and a light control layer disposed on the light emitting element and including a liquid crystal monomer and a dichroic dye. The dichroic dye in a boundary region between the sub-pixels has a black color to absorb a light.

Abstract: A display device includes: a first substrate including a pixel area and a transmissive area; a thin-film transistor on the first substrate; a planarization layer on the thin-film transistor; a first light emitting electrode on the planarization layer; a bank covering a part of the first light emitting electrode; a light emitting layer on the first light emitting electrode; and a second light emitting electrode on the light emitting layer and the bank. The transmissive area includes a transmissive hole penetrating the bank and the planarization layer.

Abstract: The present disclosure provides a method of manufacturing a hot stamping component, the method includes inserting a blank into a heating furnace, heating the blank, and transferring the heated blank from the heating furnace to a mold, wherein an air cooling time of the blank in the transferring of the blank satisfies Equation 1.

Abstract: The human body sensing device includes a contact sensing unit that includes a sensing electrode and a signal electrode, an activation module that senses a contact with a body through the sensing electrode when the sensing electrode and the signal electrode contact the body and outputs a wake-up signal in response to the sensing of the contact, and a human body communication unit that provides a ground voltage to the signal electrode and outputs a data signal to the signal electrode when the wake-up signal from the activation module is received.

Abstract: The present disclosure relates to a touch driving device, a display device including the same, and a touch management device, and more particularly, to a touch driving device which includes a panel divided into one or more separate areas and differently sets the touch sensitivities for the respective areas in order to prevent an error caused by a user's mistake, and a display device including the same and a touch management method.

Abstract: Provided are a capsule endoscopic receiving device, a capsule endoscope system including the same, and an operating method of the capsule endoscopic receiving device, the capsule endoscopic receiving device including an analog front end configured to receive a preamble from one receiving electrode pair from among a plurality of receiving electrodes, a valid signal detection circuit configured to compare a reference voltage with input data generated on a basis of a voltage level of the preamble, and a preamble processor configured to select a final electrode pair configured to receive the image data on a basis of a correlation value of the preamble and a comparison result of the input data and the reference voltage. According to the inventive concept, stability of receiving image data may be secured by selecting an optimal receiving electrode pair.

Abstract: A semiconductor device is provided. The semiconductor device includes a first insulating interlayer disposed on a first surface of a substrate; a pad pattern disposed on a lower surface of the first insulating interlayer, the pad pattern including a first copper pattern; and a through silicon via passing through the substrate and the first insulating interlayer, and contacting the first copper pattern of the pad pattern. The through silicon via includes a first portion passing through the substrate and the first insulating interlayer, and a second portion under the first portion and extending to a portion of the first copper pattern in the pad pattern. A boundary of the through silicon via has a bent portion between the first portion and the second portion.

Abstract: An organic electroluminescence device of an embodiment includes a first electrode, a second electrode and a plurality of organic layers disposed between the first electrode and the second electrode, in which at least one of the organic layers includes a polycyclic compound including a plurality of electron donors and an electron acceptor connecting the electron donors, at least one of the electron donors is a condensed ring including a borepine core, and the electron acceptor includes a phenyl group including, as a substituent, at least one cyano group or a heterocycle including at least one nitrogen atom, or a heteroaryl group including an oxygen atom or a sulfur atom for forming a ring, thereby achieving improved emission efficiency.

Abstract: A display device includes: a first substrate including a pixel area and a transmissive area; a thin-film transistor on the first substrate; a planarization layer on the thin-film transistor; a first light emitting electrode on the planarization layer; a bank covering a part of the first light emitting electrode; a light emitting layer on the first light emitting electrode; and a second light emitting electrode on the light emitting layer and the bank. The transmissive area includes a transmissive hole penetrating the bank and the planarization layer.

Abstract: The present disclosure relates to a cathode active material for a secondary battery, comprising a poly(S-co-VPA) vulcanized polymer, a preparation method thereof, and a lithium-sulfur secondary battery comprising the same.