Abstract: Described herein are compositions and methods for treating Alzheimer's disease, a tauopathy disorder or dementia. The compositions include mammalian suppressor of taupathy 2 (MSUT2) inhibitors. The methods include steps for identifying candidate compositions capable of inhibiting RNA binding proteins to poly(A) RNA and detecting RNA polyadenylation of poly(A) RNA. The methods include reducing accumulation of phosphorylated and aggregated human tau.

Abstract: A method and system for contextualizing and presenting user data. The method includes collecting information comprising service activity data and sensor data from one or more electronic devices. The information is organized based on associated time for the collected information. One or more of content information and service information of potential interest are provided to the one or more electronic devices based on one or more of user context and user activity.