Patents by Inventor Jeremy E. Wilusz

Jeremy E. Wilusz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Production of stable non-polyadenylated RNAs
    Patent number: 10946035
    Abstract: The invention relates in aspects to hybrid RNAs lacking a poly-A tail and nucleic acid vectors for expressing the RNA. The hybrid RNAs in some instances have a stabilizing triple helical structure. Related methods for expressing RNA in vivo and in vitro are also disclosed.
    Type: Grant
    Filed: July 31, 2017
    Date of Patent: March 16, 2021
    Assignee: Massachusetts Institute of Technology
    Inventors: Jeremy E. Wilusz, Phillip A. Sharp
  • PRODUCTION OF STABLE NON-POLYADENYLATED RNAS
    Publication number: 20180140625
    Abstract: The invention relates in aspects to hybrid RNAs lacking a poly-A tail and nucleic acid vectors for expressing the RNA. The hybrid RNAs in some instances have a stabilizing triple helical structure. Related methods for expressing RNA in vivo and in vitro are also disclosed.
    Type: Application
    Filed: July 31, 2017
    Publication date: May 24, 2018
    Applicant: Massachusetts Institute of Technology
    Inventors: Jeremy E. Wilusz, Phillip A. Sharp
  • Production of stable non-polyadenylated RNAs
    Patent number: 9717749
    Abstract: The invention relates in aspects to hybrid RNAs lacking a poly-A tail and nucleic acid vectors for expressing the RNA. The hybrid RNAs in some instances have a 3? terminal stabilizing triple helical structure. Related methods for expressing said RNAs in vivo and in vitro are also disclosed.
    Type: Grant
    Filed: October 16, 2013
    Date of Patent: August 1, 2017
    Assignee: Massachusetts Institute of Technology
    Inventors: Jeremy E. Wilusz, Phillip A. Sharp
  • PRODUCTION OF STABLE NON-POLYADENYLATED RNAS
    Publication number: 20150315574
    Abstract: The invention relates in aspects to hybrid RNAs lacking a poly-A tail and nucleic acid vectors for expressing the RNA. The hybrid RNAs in some instances have a 3? terminal stabilizing triple helical structure. Related methods for expressing said RNAs in vivo and in vitro are also disclosed.
    Type: Application
    Filed: October 16, 2013
    Publication date: November 5, 2015
    Applicant: Massachusetts Institute of Technology
    Inventors: Jeremy E. Wilusz, Phillip A. Sharp