Abstract: Disclosed are optical trains for imaging systems. More particularly described are imaging systems configured to limit optical aberrations. Also disclosed are methods of limiting optical aberrations in imaging systems.

Abstract: This disclosure relates generally to detecting multiple biomarkers on or within a sample, though more specifically, to detecting individual detection moieties within a plurality of detection moieties.

Abstract: This disclosure relates generally to optical trains for imaging systems. More particularly, this disclosure relates to imaging systems configured to limit optical aberrations. Furthermore, this disclosure relates to methods of limiting optical aberrations in imaging systems configured for imaging a sample, though more specifically, for detecting individual detection moieties within a plurality of detection moieties.

Abstract: This disclosure is directed to a system and method for changing an angle of incidence of a filter or filter wheel.

Abstract: This disclosure relates generally to detecting multiple biomarkers on or within a sample, though more specifically, to detecting individual detection moieties within a plurality of detection moieties.

Abstract: This disclosure relates generally to detecting multiple biomarkers on or within a sample, though more specifically, to detecting individual detection moieties within a plurality of detection moieties. A system and a process are disclosed by which individual detection moieties can be distinguished from a plurality of detection moieties (i.e., during multiplexing), such as by distinguishing the detection moieties orthogonally—in that there is no ambiguity as to which detection moiety is being detected and/or imaged. A feature of a signal of interest, such as from a detection moiety of interest, can be distinguished in the presence of a featureless signal (i.e., the signal has an unknown value and/or structure), such as from background, autofluorescence, or a non-desired detection moiety.

Abstract: This disclosure relates generally to detecting multiple biomarkers on or within a sample, though more specifically, to detecting individual detection moieties within a plurality of detection moieties. A system and a process are disclosed by which individual detection moieties can be distinguished from a plurality of detection moieties (i.e., during multiplexing), such as by distinguishing the detection moieties orthogonally—in that there is no ambiguity as to which detection moiety is being detected and/or imaged. A feature of a signal of interest, such as from a detection moiety of interest, can be distinguished in the presence of a featureless signal (i.e., the signal has an unknown value and/or structure), such as from background, autofluorescence, or a non-desired detection moiety.

Abstract: This disclosure relates generally to detecting multiple biomarkers on or within a sample, though more specifically, to detecting individual detection moieties within a plurality of detection moieties.