Patents by Inventor Jerry A. Nick

Jerry A. Nick has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10689703
    Abstract: The present invention is related to novel methods for categorizing and treating subjects having Acute Respiratory Distress Syndrome (ARDS).
    Type: Grant
    Filed: April 26, 2016
    Date of Patent: June 23, 2020
    Assignee: National Jewish Health
    Inventors: Jerry A. Nick, Kenneth C. Malcolm
  • Patent number: 9624543
    Abstract: The present invention is related to the novel discovery of a number of genes that were identified as systemic markers of pulmonary inflammation. This discovery allows for development of a novel tool for reliable, rapid and efficient assessment of therapeutic responses and enables design of novel therapies targeted against diseases associated with pulmonary inflammation. In one embodiment, the present invention allows quantification of therapeutic response in patients who have a disease associated with pulmonary inflammation. In preferred embodiments, the genes are CD64, ADAM9, CD36, IL32, HPSE, PLXND1, HCA112, CSPG2, TLR2, and CD163.
    Type: Grant
    Filed: July 15, 2015
    Date of Patent: April 18, 2017
    Assignee: National Jewish Health
    Inventors: Milene Saavedra, Jerry Nick
  • Publication number: 20160312285
    Abstract: The present invention is related to novel methods for categorizing and treating subjects having Acute Respiratory Distress Syndrome (ARDS).
    Type: Application
    Filed: April 26, 2016
    Publication date: October 27, 2016
    Inventors: Jerry A. Nick, Kenneth C. Malcolm
  • Patent number: 9314479
    Abstract: The invention relates to methods of inhibiting biofilm formation or reducing biofilms in a subject or on a device or surface by administering a charged compound such as a polyamino acid to a subject, device or surface. The invention also relates to compositions for inhibiting biofilm formation or reducing biofilms.
    Type: Grant
    Filed: May 5, 2015
    Date of Patent: April 19, 2016
    Assignee: National Jewish Health
    Inventors: Jerry A. Nick, Quinn M. Parks
  • Publication number: 20160068909
    Abstract: The present invention is related to the novel discovery of a number of genes that were identified as systemic markers of pulmonary inflammation. This discovery allows for development of a novel tool for reliable, rapid and efficient assessment of therapeutic responses and enables design of novel therapies targeted against diseases associated with pulmonary inflammation. In one embodiment, the present invention allows quantification of therapeutic response in patients who have a disease associated with pulmonary inflammation.
    Type: Application
    Filed: July 15, 2015
    Publication date: March 10, 2016
    Inventors: Milene Saavedra, Jerry Nick
  • Publication number: 20150366899
    Abstract: The invention relates to methods of inhibiting biofilm formation or reducing biofilms in a subject or on a device or surface by administering a charged compound such as a polyamino acid to a subject, device or surface. The invention also relates to compositions for inhibiting biofilm formation or reducing biofilms.
    Type: Application
    Filed: May 5, 2015
    Publication date: December 24, 2015
    Inventors: Jerry A. Nick, Quinn M. Parks
  • Publication number: 20150010492
    Abstract: The invention relates to methods of inhibiting biofilm formation or reducing biofilms in a subject or on a device or surface by administering a charged compound such as a polyamino acid to a subject, device or surface. The invention also relates to compositions for inhibiting biofilm formation or reducing biofilms.
    Type: Application
    Filed: May 1, 2014
    Publication date: January 8, 2015
    Applicant: National Jewish Health
    Inventors: Jerry A. Nick, Quinn M. Parks
  • Patent number: 8901167
    Abstract: Disclosed are compositions and methods for the inhibition of biofilm formation or reduction of existing or developing biofilms in a patient. These methods also inhibit the aggregation of bacteria that form biofilms in the airways. The methods include administering to a subject that has or is at risk of developing biofilms a compound or formulation that inhibits the formation or polymerization of actin microfilaments or depolymerizes actin microfilaments at or proximal to the site of biofilm formation. Such a compound can be administered in combination with a compound or formulation that inhibits the accumulation or activity of cells that are likely to undergo necrosis at or proximal to the site of biofilm formation (i.e., neutrophils). The methods and compositions can further include the use of anti-DNA and/or anti-mucin compounds, as well as other therapeutic compounds and compositions.
    Type: Grant
    Filed: October 12, 2012
    Date of Patent: December 2, 2014
    Assignee: National Jewish Health
    Inventors: Jerry A. Nick, Travis S. Walker, G. Scott Worthen
  • Patent number: 8753662
    Abstract: The invention relates to methods of inhibiting biofilm formation or reducing biofilms in a subject or on a device or surface by administering a charged compound such as a polyamino acid to a subject, device or surface. The invention also relates to compositions for inhibiting biofilm formation or reducing biofilms.
    Type: Grant
    Filed: February 14, 2008
    Date of Patent: June 17, 2014
    Assignee: National Jewish Health
    Inventors: Jerry A. Nick, Quinn M. Parks
  • Publication number: 20140005099
    Abstract: The present invention is related to the novel discovery of a number of genes that were identified as systemic markers of pulmonary inflammation. This discovery allows for development of a novel tool for reliable, rapid and efficient assessment of therapeutic responses and enables design of novel therapies targeted against diseases associated with pulmonary inflammation. In one embodiment, the present invention allows quantification of therapeutic response in patients who have a disease associated with pulmonary inflammation. In preferred embodiments, the genes are CD64, ADAM9, CD36, IL32, HPSE, PLXND1, HCA112, CSPG2, TLR2, and CD163.
    Type: Application
    Filed: May 16, 2013
    Publication date: January 2, 2014
    Applicant: National Jewish Health
    Inventors: Milene Saavedra, Jerry Nick
  • Patent number: 8465923
    Abstract: The present invention is related to the novel discovery of a number of genes that were identified as systemic markers of pulmonary inflammation. This discovery allows for development of a novel tool for reliable, rapid and efficient assessment of therapeutic responses and enables design of novel therapies targeted against diseases associated with pulmonary inflammation. In one embodiment, the present invention allows quantification of therapeutic response in patients who have a disease associated with pulmonary inflammation. In preferred embodiments, the genes are CD64, ADAM9, CD36, IL32, HPSE, PLXND1, HCA 112, CSPG2, TLR2, and CD163.
    Type: Grant
    Filed: December 16, 2011
    Date of Patent: June 18, 2013
    Assignee: National Jewish Health
    Inventors: Milene Saavedra, Jerry Nick
  • Publication number: 20120149595
    Abstract: The present invention is related to the novel discovery of a number of genes that were identified as systemic markers of pulmonary inflammation. This discovery allows for development of a novel tool for reliable, rapid and efficient assessment of therapeutic responses and enables design of novel therapies targeted against diseases associated with pulmonary inflammation. In one embodiment, the present invention allows quantification of therapeutic response in patients who have a disease associated with pulmonary inflammation. In preferred embodiments, the genes are CD64, ADAM9, CD36, IL32, HPSE, PLXND1, HCA 112, CSPG2, TLR2, and CD163.
    Type: Application
    Filed: December 16, 2011
    Publication date: June 14, 2012
    Applicant: National Jewish Health
    Inventors: Milene Saavedra, Jerry Nick
  • Patent number: 8101361
    Abstract: The present invention is related to the novel discovery of a number of genes that were identified as systemic markers of pulmonary inflammation. This discovery allows for development of a novel tool for reliable, rapid and efficient assessment of therapeutic responses and enables design of novel therapies targeted against diseases associated with pulmonary inflammation. In one embodiment, the present invention allows quantification of therapeutic response in patients who have a disease associated with pulmonary inflammation. In preferred embodiments, the genes are CD64, ADAM9, CD36, IL32, HPSE, PLXND1, HCA112, CSPG2, TLR2, and CD163.
    Type: Grant
    Filed: March 10, 2009
    Date of Patent: January 24, 2012
    Assignee: National Jewish Health
    Inventors: Milene Saavedra, Jerry Nick
  • Publication number: 20090233300
    Abstract: The present invention is related to the novel discovery of a number of genes that were identified as systemic markers of pulmonary inflammation. This discovery allows for development of a novel tool for reliable, rapid and efficient assessment of therapeutic responses and enables design of novel therapies targeted against diseases associated with pulmonary inflammation. In one embodiment, the present invention allows quantification of therapeutic response in patients who have a disease associated with pulmonary inflammation. In preferred embodiments, the genes are CD64, ADAM9, CD36, IL32, HPSE, PLXND1, HCA112, CSPG2, TLR2, and CD163.
    Type: Application
    Filed: March 10, 2009
    Publication date: September 17, 2009
    Inventors: Milene Saavedra, Jerry Nick
  • Publication number: 20080207556
    Abstract: Disclosed are compositions and methods for the inhibition of biofilm formation or reduction of existing or developing biofilms in a patient. These methods also inhibit the aggregation of bacteria that form biofilms in the airways. The methods include administering to a subject that has or is at risk of developing biofilms a compound or formulation that inhibits the formation or polymerization of actin microfilaments or depolymerizes actin microfilaments at or proximal to the site of biofilm formation. Such a compound can be administered in combination with a compound or formulation that inhibits the accumulation or activity of cells that are likely to undergo necrosis at or proximal to the site of biofilm formation (i.e., neutrophils). The methods and compositions can further include the use of anti-DNA and/or anti-mucin compounds, as well as other therapeutic compounds and compositions.
    Type: Application
    Filed: May 6, 2008
    Publication date: August 28, 2008
    Applicant: NATIONAL JEWISH MEDICAL AND RESEARCH CENTER
    Inventors: Jerry A. Nick, Travis S. Walker, G. Scott Worthen
  • Publication number: 20080199509
    Abstract: The invention relates to methods of inhibiting biofilm formation or reducing biofilms in a subject or on a device or surface by administering a charged compound such as a polyamino acid to a subject, device or surface. The invention also relates to compositions for inhibiting biofilm formation or reducing biofilms.
    Type: Application
    Filed: February 14, 2008
    Publication date: August 21, 2008
    Applicant: NATIONAL JEWISH MEDICAL AND RESEARCH CENTER
    Inventors: Jerry A. Nick, Quinn M. Parks
  • Publication number: 20060030539
    Abstract: Disclosed are compositions and methods for the inhibition of biofilm formation or reduction of existing or developing biofilms in a patient. These methods also inhibit the aggregation of bacteria that form biofilms in the airways. The methods include administering to a subject that has or is at risk of developing biofilms a compound or formulation that inhibits the formation or polymerization of actin microfilaments or depolymerizes actin microfilaments at or proximal to the site of biofilm formation. Such a compound can be administered in combination with a compound or formulation that inhibits the accumulation or activity of cells that are likely to undergo necrosis at or proximal to the site of biofilm formation (i.e., neutrophils). The methods and compositions can further include the use of anti-DNA and/or anti-mucin compounds, as well as other therapeutic compounds and compositions.
    Type: Application
    Filed: August 4, 2005
    Publication date: February 9, 2006
    Applicant: National Jewish Medical and Research Center
    Inventors: Jerry Nick, Travis Walker, G. Worthen