Patents by Inventor Jerzy Olejnik

Jerzy Olejnik has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND COMPOSITIONS FOR INCORPORATING NUCLEOTIDES
    Publication number: 20170211141
    Abstract: The invention provides methods and compositions, including, without limitation, algorithms, computer readable media, computer programs, apparatus, and systems for determining the identity of nucleic acids in nucleotide sequences using, for example, data obtained from sequencing by synthesis methods. The methods of the invention include correcting one or more phenomena that are encountered during nucleotide sequencing, such as using sequencing by synthesis methods. These phenomena include, without limitation, sequence lead, sequence lag, spectral crosstalk, and noise resulting from variations in illumination and/or filter responses.
    Type: Application
    Filed: April 5, 2017
    Publication date: July 27, 2017
    Inventors: Steven Gordon, Jerzy Olejnik
  • METHODS OF USING NUCLEOTIDE ANALOGUES
    Publication number: 20170137878
    Abstract: The present invention provides methods, compositions, mixtures and kits utilizing deoxynucleoside triphosphates comprising a 3?-O position capped by a group comprising methylenedisulfide as a cleavable protecting group and a detectable label reversibly connected to the nucleobase of said deoxynucleoside. Such compounds provide new possibilities for future sequencing technologies, including but not limited to Sequencing by Synthesis.
    Type: Application
    Filed: November 4, 2016
    Publication date: May 18, 2017
    Inventors: Mong Sano Marma, Jerzy Olejnik, IIia Korboukh
  • METHODS FOR SYNTHESIZING NUCLEOTIDE ANALOGUES WITH DISULFIDE LINKERS
    Publication number: 20170137869
    Abstract: The present invention provides methods, compositions, mixtures and kits utilizing deoxynucleoside triphosphates comprising a 3?-O position capped by a group comprising methylenedisulfide as a cleavable protecting group and a detectable label reversibly connected to the nucleobase of said deoxynucleoside. Such compounds provide new possibilities for future sequencing technologies, including but not limited to Sequencing by Synthesis.
    Type: Application
    Filed: November 4, 2016
    Publication date: May 18, 2017
    Inventors: Mong Sano Marma, Jerzy Olejnik, llia Korboukh
  • NUCLEOTIDE ANALOGUES
    Publication number: 20170130051
    Abstract: The present invention provides methods, compositions, mixtures and kits utilizing deoxynucleoside triphosphates comprising a 3?-O position capped by a group comprising methylenedisulfide as a cleavable protecting group and a detectable label reversibly connected to the nucleobase of said deoxynucleoside. Such compounds provide new possibilities for future sequencing technologies, including but not limited to Sequencing by Synthesis.
    Type: Application
    Filed: November 4, 2016
    Publication date: May 11, 2017
    Inventors: Mong Sano Marma, Jerzy Olejnik, Ilia Korboukh
  • Methods and compositions for incorporating nucleotides
    Patent number: 9644237
    Abstract: The invention provides methods and compositions, including, without limitation, algorithms, computer readable media, computer programs, apparatus, and systems for determining the identity of nucleic acids in nucleotide sequences using, for example, data obtained from sequencing by synthesis methods. The methods of the invention include correcting one or more phenomena that are encountered during nucleotide sequencing, such as using sequencing by synthesis methods. These phenomena include, without limitation, sequence lead, sequence lag, spectral crosstalk, and noise resulting from variations in illumination and/or filter responses.
    Type: Grant
    Filed: May 2, 2016
    Date of Patent: May 9, 2017
    Assignee: INTELLIGENT BIO-SYSTEMS, Inc.
    Inventors: Steven Gordon, Jerzy Olejnik
  • Methods and solutions for inhibiting undesired cleaving of labels
    Patent number: 9605301
    Abstract: The invention provides methods and compositions, including, without limitation, algorithms, computer readable media, computer programs, apparatus, and systems for determining the identity of nucleic acids in nucleotide sequences using, for example, data obtained from sequencing by synthesis methods. The methods of the invention include correcting one or more phenomena that are encountered during nucleotide sequencing, such as using sequencing by synthesis methods. These phenomena include, without limitation, sequence lead, sequence lag, spectral crosstalk, and noise resulting from variations in illumination and/or filter responses.
    Type: Grant
    Filed: August 11, 2014
    Date of Patent: March 28, 2017
    Assignee: Intelligent Bio-Systems, Inc.
    Inventors: Jerzy Olejnik, Evan Guggenheim, Visalakshi Meyyappan
  • Methods And Compositions For Incorporating Nucleotides
    Publication number: 20170029884
    Abstract: The invention provides methods and compositions, including, without limitation, algorithms, computer readable media, computer programs, apparatus, and systems for determining the identity of nucleic acids in nucleotide sequences using, for example, data obtained from sequencing by synthesis methods. The methods of the invention include correcting one or more phenomena that are encountered during nucleotide sequencing, such as using sequencing by synthesis methods. These phenomena include, without limitation, sequence lead, sequence lag, spectral crosstalk, and noise resulting from variations in illumination and/or filter responses.
    Type: Application
    Filed: July 20, 2016
    Publication date: February 2, 2017
    Inventors: Steven Gordon, Jerzy Olejnik
  • MODULAR FLOW CELLS AND METHODS OF SEQUENCING
    Publication number: 20170022555
    Abstract: Modular flow cells, devices with modular flow cells, and methods of sequencing using modular flow cells, as well as systems and kits including modular flow cells, are described, permitting sequencing wherein less than the full capacity for sequencing is desired.
    Type: Application
    Filed: July 20, 2016
    Publication date: January 26, 2017
    Inventors: Jerzy Olejnik, Dirk Zimmerman
  • Methods And Compositions For Incorporating Nucleotides
    Publication number: 20160348165
    Abstract: The invention provides methods and compositions, including, without limitation, algorithms, computer readable media, computer programs, apparatus, and systems for determining the identity of nucleic acids in nucleotide sequences using, for example, data obtained from sequencing by synthesis methods. The methods of the invention include correcting one or more phenomena that are encountered during nucleotide sequencing, such as using sequencing by synthesis methods. These phenomena include, without limitation, sequence lead, sequence lag, spectral crosstalk, and noise resulting from variations in illumination and/or filter responses.
    Type: Application
    Filed: May 2, 2016
    Publication date: December 1, 2016
    Inventors: Steven Gordon, Jerzy Olejnik
  • Hydroxymethyl Linkers For Labeling Nucleotides
    Publication number: 20160326579
    Abstract: The invention provides methods and compositions, including, without limitation, algorithms, computer readable media, computer programs, apparatus, and systems for determining the identity of nucleic acids in nucleotide sequences using, for example, data obtained from sequencing by synthesis methods. The methods of the invention include correcting one or more phenomena that are encountered during nucleotide sequencing, such as using sequencing by synthesis methods. These phenomena include, without limitation, sequence lead, sequence lag, spectral crosstalk, and noise resulting from variations in illumination and/or filter responses.
    Type: Application
    Filed: April 20, 2016
    Publication date: November 10, 2016
    Inventor: Jerzy Olejnik
  • Methods and compositions for incorporating nucleotides
    Patent number: 9434989
    Abstract: The invention provides methods and compositions, including, without limitation, algorithms, computer readable media, computer programs, apparatus, and systems for determining the identity of nucleic acids in nucleotide sequences using, for example, data obtained from sequencing by synthesis methods. The methods of the invention include correcting one or more phenomena that are encountered during nucleotide sequencing, such as using sequencing by synthesis methods. These phenomena include, without limitation, sequence lead, sequence lag, spectral crosstalk, and noise resulting from variations in illumination and/or filter responses.
    Type: Grant
    Filed: April 20, 2015
    Date of Patent: September 6, 2016
    Assignee: INTELLIGENT BIO-SYSTEMS, INC.
    Inventors: Steven Gordon, Jerzy Olejnik
  • Methods and Compositions for Sequencing Nucleic Acids Using Charge
    Publication number: 20160222446
    Abstract: The invention provides methods and compositions, and systems for determining the identity of nucleic acids in nucleotide sequences, including sequences with one or more homopolymer regions. The methods of the invention include improvements so as to accurately identify sequences, including the difficult homopolymer sequences that are encountered during nucleotide sequencing, such as pyrosequencing.
    Type: Application
    Filed: April 11, 2016
    Publication date: August 4, 2016
    Inventors: Steven Gordon, Jerzy Olejnik
  • Methods and compositions for incorporating nucleotides
    Patent number: 9399799
    Abstract: The invention provides methods and compositions, including, without limitation, algorithms, computer readable media, computer programs, apparatus, and systems for determining the identity of nucleic acids in nucleotide sequences using, for example, data obtained from sequencing by synthesis methods. The methods of the invention include correcting one or more phenomena that are encountered during nucleotide sequencing, such as using sequencing by synthesis methods. These phenomena include, without limitation, sequence lead, sequence lag, spectral crosstalk, and noise resulting from variations in illumination and/or filter responses.
    Type: Grant
    Filed: October 20, 2014
    Date of Patent: July 26, 2016
    Assignee: INTELLIGENT BIOSYSTEMS, INC.
    Inventors: Steven Gordon, Jerzy Olejnik
  • Hydroxymethyl linkers for labeling nucleotides
    Patent number: 9322050
    Abstract: The invention provides methods and compositions, including, without limitation, algorithms, computer readable media, computer programs, apparatus, and systems for determining the identity of nucleic acids in nucleotide sequences using, for example, data obtained from sequencing by synthesis methods. The methods of the invention include correcting one or more phenomena that are encountered during nucleotide sequencing, such as using sequencing by synthesis methods. These phenomena include, without limitation, sequence lead, sequence lag, spectral crosstalk, and noise resulting from variations in illumination and/or filter responses.
    Type: Grant
    Filed: July 25, 2013
    Date of Patent: April 26, 2016
    Assignee: Intelligent Bio-Systems, Inc.
    Inventor: Jerzy Olejnik
  • Methods and compositions for sequencing nucleic acid using charge
    Patent number: 9309569
    Abstract: The invention provides methods and compositions, and systems for determining the identity of nucleic acids in nucleotide sequences, including sequences with one or more homopolymer regions. The methods of the invention include improvements so as to accurately identify sequences, including the difficult homopolymer sequences that are encountered during nucleotide sequencing, such as pyrosequencing.
    Type: Grant
    Filed: August 18, 2011
    Date of Patent: April 12, 2016
    Assignee: Intelligent Bio-Systems, Inc.
    Inventors: Steven Gordon, Jerzy Olejnik
  • Methods And Devices For Sequencing Nucleic Acids In Smaller Batches
    Publication number: 20150316505
    Abstract: The invention provides methods and compositions, including, without limitation, algorithms, computer readable media, computer programs, apparatus, and systems for determining the identity of nucleic acids in nucleotide sequences using, for example, data obtained from sequencing by synthesis methods. A plurality of smaller flow cells is employed, each with a relatively small area to be imaged, in order to provide greater flexibility and efficiency.
    Type: Application
    Filed: May 11, 2015
    Publication date: November 5, 2015
    Inventors: Steven Gordon, Thomas Hagerott, Edmund Golaski, Jerzy Olejnik
  • Methods and Compositions for Incorporating Nucleotides
    Publication number: 20150299783
    Abstract: The invention provides methods and compositions, including, without limitation, algorithms, computer readable media, computer programs, apparatus, and systems for determining the identity of nucleic acids in nucleotide sequences using, for example, data obtained from sequencing by synthesis methods. The methods of the invention include correcting one or more phenomena that are encountered during nucleotide sequencing, such as using sequencing by synthesis methods. These phenomena include, without limitation, sequence lead, sequence lag, spectral crosstalk, and noise resulting from variations in illumination and/or filter responses.
    Type: Application
    Filed: April 20, 2015
    Publication date: October 22, 2015
    Inventors: Steven Gordon, Jerzy Olejnik
  • Methods and devices for sequencing nucleic acids in smaller batches
    Patent number: 9145589
    Abstract: The invention provides methods and compositions, including, without limitation, algorithms, computer readable media, computer programs, apparatus, and systems for determining the identity of nucleic acids in nucleotide sequences using, for example, data obtained from sequencing by synthesis methods. A plurality of smaller flow cells is employed, each with a relatively small area to be imaged, in order to provide greater flexibility and efficiency.
    Type: Grant
    Filed: August 19, 2014
    Date of Patent: September 29, 2015
    Assignee: Intelligent Biosystems, Inc.
    Inventors: Steven Gordon, Thomas Hagerott, Edmund Golaski, Jerzy Olejnik
  • Methods And Compositions For Incorporating Nucleotides
    Publication number: 20150191783
    Abstract: The invention provides methods and compositions, including, without limitation, algorithms, computer readable media, computer programs, apparatus, and systems for determining the identity of nucleic acids in nucleotide sequences using, for example, data obtained from sequencing by synthesis methods. The methods of the invention include correcting one or more phenomena that are encountered during nucleotide sequencing, such as using sequencing by synthesis methods. These phenomena include, without limitation, sequence lead, sequence lag, spectral crosstalk, and noise resulting from variations in illumination and/or filter responses.
    Type: Application
    Filed: October 20, 2014
    Publication date: July 9, 2015
    Inventors: STEVEN GORDON, JERZY OLEJNIK
  • Methods and compositions for incorporating nucleotides
    Patent number: 9017973
    Abstract: The invention provides methods and compositions, including, without limitation, algorithms, computer readable media, computer programs, apparatus, and systems for determining the identity of nucleic acids in nucleotide sequences using, for example, data obtained from sequencing by synthesis methods. The methods of the invention include correcting one or more phenomena that are encountered during nucleotide sequencing, such as using sequencing by synthesis methods. These phenomena include, without limitation, sequence lead, sequence lag, spectral crosstalk, and noise resulting from variations in illumination and/or filter responses.
    Type: Grant
    Filed: November 28, 2011
    Date of Patent: April 28, 2015
    Assignee: Intelligent BioSystems, Inc.
    Inventors: Steven Gordon, Jerzy Olejnik