Abstract: The present invention relates to the art of dispensing medicine to a user of medicine, and relates in particular to a medicine dispenser for dispensing doses of medicaments, a loader for loading doses of medicine into the medicine dispenser, a medicine distribution box, a packing device for packing medicaments in predefined doses, a Central Medication Database and a system comprising all these objects. Furthermore, the invention relates to a method of dispensing doses of medicaments, a method of loading medicine into a medicine dispenser, a method of distributing medicine, a method of packing medicaments in predefined doses, a method of carrying out various aspects related to dispensing medicine as well as a method integrating all the above mentioned methods.