Patents by Inventor Jesse A. May

Jesse A. May has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 5-Hydroxy indazole derivatives for treating glaucoma
    Publication number: 20060052431
    Abstract: 3-(2-aminoethyl)-1H-indazol-5-ols useful for treating elevated intraocular pressure and glaucoma are disclosed.
    Type: Application
    Filed: November 2, 2005
    Publication date: March 9, 2006
    Inventors: Jesse May, Zixia Feng
  • Aminoalkyl-benzofuran-5-ol compounds for the treatment of glaucoma
    Patent number: 7005448
    Abstract: The present invention provides novel compounds, compositions containing the compounds of the invention in a pharmaceutically acceptable excipient and methods for using the compositions for lowering intraocular pressure.
    Type: Grant
    Filed: December 5, 2002
    Date of Patent: February 28, 2006
    Assignee: Alcon, Inc.
    Inventor: Jesse A. May
  • 5-Hydroxy indazole derivatives for treating glaucoma
    Patent number: 7005443
    Abstract: 3-(2-aminoethyl)-1H-indazol-5-ols useful for treating elevated intraocular pressure and glaucoma are disclosed.
    Type: Grant
    Filed: November 14, 2000
    Date of Patent: February 28, 2006
    Assignee: Alcon, Inc.
    Inventors: Jesse A. May, Zixia Feng
  • Substituted [1,4]oxazino[2,3-g]indazoles for the treatment of glaucoma
    Publication number: 20050277636
    Abstract: Substituted [1,4]oxazino[2,3-g]indazols for lowering intraocular pressure and treating glaucoma are disclosed.
    Type: Application
    Filed: July 13, 2005
    Publication date: December 15, 2005
    Inventors: Anura Dantanarayana, Jesse May
  • Fused indazoles and indoles and their use for the treatment of glaucoma
    Patent number: 6960608
    Abstract: Novel fused indazoles and indoles are disclosed. Also disclosed are methods for the lowering and controlling of normal or elevated intraocular pressure as well as a method for the treatment of glaucoma using compositions containing one or more of the compounds of the present invention.
    Type: Grant
    Filed: November 25, 2003
    Date of Patent: November 1, 2005
    Assignee: Alcon, Inc.
    Inventors: Jesse A. May, Anura P. Dantanarayana
  • Serotonergic 5HTreceptor compounds for treating ocular and CNS disorders
    Patent number: 6960579
    Abstract: Compounds with 5HT7 receptor affinity (some of which are novel) useful for lowering IOP, improving blood flow to the optic nerve head and the retina, providing neuroprotection, and treating retinal diseases are disclosed. The Compounds are also useful for treating sleep disorders, depression, and other psychiatric disorders, such as, schizophrenia, anxiety, obsessive compulsive disorder, circadian rhythm disorders, and centrally and peripherally mediated hypertension. Compositions and methods for their use are also disclosed.
    Type: Grant
    Filed: May 10, 1999
    Date of Patent: November 1, 2005
    Assignee: Alcon Manufacturing, Ltd.
    Inventors: Jesse A. May, Thomas R. Dean, Najam A. Sharif, Hwang-Hsing Chen
  • Use of MDCK cell line to predict corneal penetration of drugs
    Publication number: 20050239050
    Abstract: A new method of evaluating the ability of drug molecules to penetrate the cornea is described. The permeation rate of the drug molecules in MDCK cells is utilized to predict the ability of the molecules to penetrate the cornea. The method is useful for in vitro screening of potential new ophthalmic drugs, as well as in the design of new drug molecules for topical ocular administration.
    Type: Application
    Filed: April 25, 2005
    Publication date: October 27, 2005
    Inventors: Andrew Rusinko, Mark Hellberg, Jesse May, Geoffrey Owen
  • 6-hydroxy-indazole derivatives for treating glaucoma
    Patent number: 6956036
    Abstract: Substituted 1-(?-alkyl-ethylamino)-1H-indazol-6-ols useful for lowering and controlling IOP and treating glaucoma are disclosed
    Type: Grant
    Filed: November 14, 2000
    Date of Patent: October 18, 2005
    Assignee: Alcon, Inc.
    Inventors: Jesse A. May, Zixia Feng, Anura P. Dantanarayana
  • Serotonergic 5HT7 receptor compounds for treating ocular and CNS disorders
    Publication number: 20050187214
    Abstract: Compounds with 5HT7 receptor affinity (some of which are novel) useful for lowering IOP, improving blood flow to the optic nerve head and the retina, providing neuroprotection, and treating retinal diseases are disclosed. The Compounds are also useful for treating sleep disorders, depression, and other psychiatric disorders, such as, schizophrenia, anxiety, obsessive compulsive disorder, circadian rhythm disorders, and centrally and peripherally mediated hypertension. Compositions and methods for their use are also disclosed.
    Type: Application
    Filed: April 7, 2005
    Publication date: August 25, 2005
    Inventors: Jesse May, Thomas Dean, Najam Sharif, Hwang-Hsing Chen
  • Hydroxy substituted fused naphthyl-azoles and fused indeno-azoles and their use for the treatment of glaucoma
    Patent number: 6933392
    Abstract: Hydroxy substituted fused naphthyl-azoles and fused indeno-azoles are disclosed. Also disclosed are methods for the lowering and controlling of normal or elevated intraocular pressure as well as a method for the treatment of glaucoma using compositions containing one or more of the compounds of the present invention.
    Type: Grant
    Filed: May 28, 2003
    Date of Patent: August 23, 2005
    Assignee: Alcon, Inc.
    Inventors: Jesse A. May, Paul W. Zinke
  • 5ht2 agonists for controlling IOP and treating glaucoma
    Patent number: 6927233
    Abstract: Compositions and methods for controlling intraocular pressure and treating glaucoma using 1-(2-aminopropyl)-indazol-6-ol are disclosed.
    Type: Grant
    Filed: November 14, 2000
    Date of Patent: August 9, 2005
    Assignees: Alcon, Inc., Yamanouchi Pharmaceutical Co., Ltd.
    Inventors: Jesse A. May, Anura P. Dantanarayana
  • Substituted 5-chroman-5-YL-ethylamine compounds and their use for the treatment of glaucoma
    Publication number: 20050171190
    Abstract: Substituted 5-chroman-5-yl-ethylamine compounds are disclosed. Also disclosed are methods for the lowering and controlling of normal or elevated intraocular pressure as well as a method for the treatment of glaucoma using compositions containing one or more of the compounds of the present invention.
    Type: Application
    Filed: February 23, 2005
    Publication date: August 4, 2005
    Inventors: Jesse May, Anura Dantanarayana
  • Substituted [1,4]oxazino[2,3-g]indazoles for the treatment of glaucoma
    Publication number: 20050130960
    Abstract: Substituted [1,4]oxazino[2,3-g]indazols for lowering intraocular pressure and treating glaucoma are disclosed.
    Type: Application
    Filed: December 14, 2004
    Publication date: June 16, 2005
    Inventors: Anura Dantanarayana, Jesse May
  • Hydroxy substituted fused naphthyl-azoles and fused indeno-azoles and their use for the treatment of glaucoma
    Patent number: 6884816
    Abstract: Hydroxy substituted fused naphthyl-azoles and fused indeno-azoles are disclosed. Also disclosed are methods for the lowering and controlling of normal or elevated intraocular pressure as well as a method for the treatment of glaucoma using compositions containing one or more of the compounds of the present invention.
    Type: Grant
    Filed: August 30, 2002
    Date of Patent: April 26, 2005
    Assignee: Alcon, Inc.
    Inventors: Jesse A. May, Paul W. Zinke
  • Pyranoindazoles and their use for the treatment of glaucoma
    Patent number: 6881749
    Abstract: Pyranoindazoles are disclosed. Also disclosed are methods for the lowering and controlling of normal or elevated intraocular pressure as well as a method for the treatment of glaucoma using compositions containing one or more of the compounds of the present invention.
    Type: Grant
    Filed: November 24, 2003
    Date of Patent: April 19, 2005
    Assignee: Alcon, Inc.
    Inventors: Hwang-Hsing Chen, Jesse A. May, Bryon S. Severns
  • 5-Hydroxyl indole derivatives for treating glaucoma
    Patent number: 6806285
    Abstract: Novel 3-(2-aminopropyl)-H-indol-5-ols useful for lowering and controlling IOP and treating glaucoma are disclosed.
    Type: Grant
    Filed: September 5, 2002
    Date of Patent: October 19, 2004
    Assignee: Alcon, Inc.
    Inventors: Jesse A. May, Paul W. Zinke
  • Use of cloprostenol and fluprostenol analogues to treat glaucoma and ocular hypertension
    Publication number: 20040198817
    Abstract: Disclosed is the use of cloprostenol and fluprostenol analogues in combination with carbonic anhydrase inhibitors for the treatment of glaucoma and ocular hypertension and ophthalmic compositions therefor.
    Type: Application
    Filed: April 20, 2004
    Publication date: October 7, 2004
    Inventors: Peter G. Klimko, John E. Bishop, Verney L. Sallee, Paul W. Zinke, George E. Barnes, Michael L. Chandler, Thomas R. Dean, Jesse A. May, Louis Desantis
  • Pyranoindazoles and their use for the treatment of glaucoma
    Publication number: 20040106609
    Abstract: Pyranoindazoles are disclosed. Also disclosed are methods for the lowering and controlling of normal or elevated intraocular pressure as well as a method for the treatment of glaucoma using compositions containing one or more of the compounds of the present invention.
    Type: Application
    Filed: November 24, 2003
    Publication date: June 3, 2004
    Inventors: Hwang-Hsing Chen, Jesse A. May, Bryon S. Severns
  • Novel fused indazoles and indoles and their use for the treatment of glaucoma
    Publication number: 20040106597
    Abstract: Novel fused indazoles and indoles are disclosed. Also disclosed are methods for the lowering and controlling of normal or elevated intraocular pressure as well as a method for the treatment of glaucoma using compositions containing one or more of the compounds of the present invention.
    Type: Application
    Filed: November 25, 2003
    Publication date: June 3, 2004
    Inventors: Jesse A. May, Anura P. Dantanarayana
  • Pyranoindazoles and their use for the treatment of glaucoma
    Patent number: 6696476
    Abstract: Pyranoindazoles are disclosed. Also disclosed are methods for the lowering and controlling of normal or elevated intraocular pressure as well as a method for the treatment of glaucoma using compositions containing one or more of the compounds of the present invention.
    Type: Grant
    Filed: December 11, 2002
    Date of Patent: February 24, 2004
    Assignee: Alcon, Inc.
    Inventors: Hwang-Hsing Chen, Jesse A. May, Bryon S. Severns