Patents by Inventor Jesse Boehm

Jesse Boehm has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMBINATORIAL CULTURE CONDITION ARRAYS AND USES THEREOF
    Publication number: 20220034870
    Abstract: Described in certain embodiments herein are combinatorial addressable arrays configured for high-throughput analysis of a sample and methods of using said combinatorial addressable arrays. Also described herein in certain embodiments are computer-implemented methods of training a statistical or machine learning model for determining and/or predicting culture conditions effective for growth of a biologic sample and computer-implemented method to determine and/or predict culture conditions effective growth for growth of a biologic sample.
    Type: Application
    Filed: July 28, 2021
    Publication date: February 3, 2022
    Inventors: Jesse Boehm, Yuen-Yi Tseng
  • LIVING BIOSENSORS
    Publication number: 20210190762
    Abstract: Ex vivo cell-based living biosensors, methods of imaging and identifying cell types and/or cell phenotypes, and uses of the systems and methods are provided.
    Type: Application
    Filed: December 7, 2020
    Publication date: June 24, 2021
    Inventors: Jesse Boehm, Niklas Rindtorff, JT Neal, Aviad Tsherniak, Mushriq Muhib Al-Jazrawe
  • METHODS AND COMPOSITIONS FOR MASSIVELY PARALLEL VARIANT AND SMALL MOLECULE PHENOTYPING
    Publication number: 20200283843
    Abstract: The present invention provides methods and tools for analyzing genetic interactions. The subject matter is generally directed to single-cell genomics and proteomics, including methods of performing genome-wide CRISPR perturbation screens and determining gene expression phenotypes.
    Type: Application
    Filed: March 4, 2020
    Publication date: September 10, 2020
    Inventors: Aviv Regev, Pratiksha Thakore, John Doench, JT Neal, Jesse Boehm, Oana Ursu
  • Compositions and methods for identifying transforming and tumor suppressor genes
    Patent number: 8178317
    Abstract: Provided herein are nucleic acids, proteins, vectors, cells, kits, devices and methods useful for identifying regulatable proteins that are able to complement components of cellular signaling pathways. Also provided are compositions and methods using these complementing genes directly as markers for cancer diagnosis or prognosis and as targets for anti-neoplastic therapeutics. Further provided are methods for using changes caused by expression of the complementing genes to indirectly identify associated genes to be used as markers for cancer diagnosis or prognosis and as targets for anti-neoplastic therapeutics.
    Type: Grant
    Filed: May 1, 2008
    Date of Patent: May 15, 2012
    Assignee: Dana-Farber Cancer Institute, Inc.
    Inventors: Thomas M. Roberts, Jean Zhao, David E. Hill, William C. Hahn, Jesse Boehm
  • Compositions and methods for indentifying transforming and tumor suppressor genes
    Publication number: 20090047675
    Abstract: Provided herein are nucleic acids, proteins, vectors, cells, kits, devices and methods useful for identifying regulatable proteins that are able to complement components of cellular signaling pathways. Also provided are compositions and methods using these complementing genes directly as markers for cancer diagnosis or prognosis and as targets for anti-neoplastic therapeutics. Further provided are methods for using changes caused by expression of the complementing genes to indirectly identify associated genes to be used as markers for cancer diagnosis or prognosis and as targets for anti-neoplastic therapeutics.
    Type: Application
    Filed: May 1, 2008
    Publication date: February 19, 2009
    Applicant: Dana-Farber Cancer Institute, Inc.
    Inventors: Thomas M. Roberts, Jean Zhao, David E. Hill, William C. Hahn, Jesse Boehm