Abstract: A method for producing a two-component polyurethane composition comprising at least one additive soluble in polar solvents, in particular a biocide, comprising the following steps: a) providing at least one polyol; b) adding at least one solution of the polar solvent comprising at least one additive soluble in polar solvents, in particular a biocide, and at least one carrier material for the additive to the polyol from step a); and c) providing, in accordance with the requirements, at least one isocyanate for adding to the mixture from step b). The method has the advantage that additives can be incorporated into a two-component polyurethane composition without agglomerating or precipitating, without side reactions, and without an additional drying step.

Abstract: The present invention relates to resorbable membranes for medical uses. The membranes according to the present invention are produced or producible from a composition comprising at least one polyol component, at least one polyisocyanate component and an additive selected from polyvinylpyrrolidone, polyvinylpolypyrrolidone, a copolymer of polyvinylpyrrolidone with vinylacetate, vinylimidazole or vinylcaprolactam or mixtures thereof. The present invention further relates to a kit comprising a multitude of membranes with different absorption rates.

Abstract: The invention relates to a wound closure material with a core of biodegradable material, wherein at least one side, preferably two sides of the core of biodegradable material are provided with at least one, preferably a multitude of discrete spots of an adhesive. As with more common wound closure techniques like sutures, clips and tapes applied over the wound, new tissue has to close a gap between the wound edges. Use of a wound closing material of the present invention does not only have the advantage of a secure physical connection between the edges, but the material serves as scaffolding for the new tissue. It may also serve the cells as artificial extracellular matrix they can adhere to.

Abstract: The present invention relates to a biocompatible, resorbable polyurethane foam wound cover with open pores and an adjustable resorption rate having improved properties when used on skin or connective tissue wounds as well as a method of production of such a polyurethane foam wound cover.