Abstract: The invention pertains to the use of lonafarnib or any analog or derivative thereof for the treatment of a viral disease characterized by a viral entry into a host cell via a viral fusion glycoprotein (F-protein). In particular, the invention provides treatments of human respiratory syncytial virus (HRSV) caused diseases comprising the administration (use) of lonafarnib or its analogs or derivatives, as well as pharmaceutical compositions comprising lonafarnib or its analogs and derivates.

Abstract: An annular cutter catching device includes a housing having an inner bore therethrough, a cutter configured to cut a coupon, and a coupon catching device configured to grip an outer surface of the coupon. In an embodiment, an annular cutter catching device includes one or more split rings disposed within the inner bore of the housing. In the embodiment, at least one split ring is configured to grip an outer surface of the coupon within the inner bore of the housing. In an embodiment, an annular cutter catching device includes a coupon catcher disposed within the inner bore of the housing. In an embodiment, the coupon catcher includes a set of fingers movable between an open position and a closed position. In an embodiment, the set of fingers are configured to retain the coupon within the inner bore of the housing in the closed position.

Abstract: The invention relates to a method for compensating patient movements in MRI scans in real time and to a device suitable for carrying out said method. The method involves the following steps: optically sensing a marking element (5) connected to a patient (3) by means of an image sensor module (7) of an MRI-compatible camera (2) which is positioned inside an MRI device; transferring the image data detected by the image sensor module (7) to a micro-controller module (11) which is integrated in the MRI-compatible camera (2); calculating position data of the marking element (5) in the micro-controller module (11); and transmitting the position data to an external analyzing unit or to the MRI device in real time.

Abstract: The invention relates to a method for compensating patient movements in MRI scans in real time and to a device suitable for carrying out said method. The method involves the following steps: optically sensing a marking element (5) connected to a patient (3) by means of an image sensor module (7) of an MRI-compatible camera (2) which is positioned inside an MRI device; transferring the image data detected by the image sensor module (7) to a micro-controller module (11) which is integrated in the MRI-compatible camera (2); calculating position data of the marking element (5) in the micro-controller module (11); and transmitting the position data to an external analyzing unit or to the MRI device in real time.