Abstract: This invention describes ways of obtaining nano-particulated adjuvants formed by different synthetic variants of GM3 ganglioside. Depending on the fine structure of the fatty acid in the ceramide of the synthetic GM3, said adjuvants are able to stimulate specifically and in a specialized way the humoral or cellular immune response against accompanying antigens. Particularly, this invention provides immunogenic vaccine compositions that comprise peptides, polypeptides or proteins and the aforementioned nanoparticles, which are formed through the dispersion of hydrophobic proteins of the outer membrane complex (OMC) of Neisseria meningitidis in solutions containing fully synthetic variants of the GM3 ganglioside.

Abstract: An apparatus for safely and efficiently purging refrigerant lines interconnected with residential and light commercial air conditioning systems. Enhanced safety is achieved by enabling the operator to conduct purge operations away from enclosed areas such as attics and crawlspaces. Efficient use of solvent is achieved by simultaneously connecting a refrigerant line connector to the evaporator end of both suction line and liquid line and discharging solvent and compressed gas through a solvent bridge connected to the compressor end of the liquid line. Thorough contaminant removal enables retrofitting air conditioning systems for use with newer, legally required refrigerants.