Abstract: A vehicle includes a body defining a cabin interior, a seat assembly having a seat base, a seat back and a plurality of actuators configured to adjust ergonomic positions of the seat assembly. The vehicle has a first imaging system located in the cabin interior and configured to capture first images of an upper body of an occupant seated on the seat assembly, and a second imaging system configured to capture second images of a lower body of the occupant seated on the seat assembly. A controller processes the first and second images to determine dimension data and position data of the occupant and determines an adjusted ergonomic configuration of the seating assembly, and controls the actuators to adjust the seat assembly to the adjusted ergonomic configuration.

Abstract: An aspect of the disclosure provides for an optical-phased array (OPA) comprising a star coupler coupled to a plurality of grating couplers, wherein the star coupler comprises multiple inputs and multiple outputs. In some embodiments, each output of the star coupler is coupled to a grating coupler of the plurality of grating couplers. In some embodiments, the star coupler is coupled to the plurality of grating couplers by a plurality of optical delay lines. In some embodiments each output of the star coupler is coupled to a grating coupler of the plurality of grating couplers via an optical delay line of the plurality of optical delay lines. In some embodiments, the OPA further includes an optical switch coupled to the multiple inputs of the star coupler, and at least one tunable laser. Another aspect of the disclosure provides a method for steering light using the OPA.

Abstract: The present invention relates to bedding product having heat-dissipation and support properties provided by structural protrusions on the surface of the bedding product. The bedding product may comprise a first layer of foam, that includes a base support having an upper surface and a lower surface and a plurality of open and closed protrusions located on the upper surface of the base support. Each open protrusion comprises a cavity formed therein, wherein the cavity has a depth of at least 0.

Abstract: In example implementations, an apparatus is provided. The apparatus includes a shipment delay detection component, a root cause identification component, a data scrubber, and a notification generator. The shipment delay detection component is to detect a shipment delay of an order. The root cause identification component is to identify a root cause of the shipment delay. The data scrubber is to initiate a communication session with a server in a region associated with the root cause to obtain missing data. The notification generator is to generate a notification comprising the root cause and the missing data.

Abstract: The present disclosure relates to the use of the non-toxic proteolytic C fragment of tetanus toxin and plasmids encoding such protein fragment to increase muscle mass and/or muscle strength in a subject in need thereof. As such, methods of ameliorating the severity of a pathological condition characterized, at least in part, by a decreased amount, development, or metabolic activity of muscle are provided. The disclosed compositions and method are also useful for the treatment of condition in which increase in muscle mass and muscle strength are desirable, including cosmetic uses.

Abstract: The present invention relates to the use of the inhibitor of the activity of the steroid sulfatase enzyme STX64 for the treatment of ageing and, therefore, to increase the longevity of individuals or improve their quality of life. It also relates to a cosmetic composition that comprises said inhibitor for that purpose.

Abstract: A hand held flossing device with a handle that is asymmetrically curved, such that when the device is oriented to clean between the lower back teeth, the axis of the handle is curved sideways and downwards away from the mouth. The curvature of the handle may also continue into the neck of the device. The handle also has a bulbous portion having an enlarged surface area for gripping firmly with minimal force. This provides for improved comfort and easier use, allowing the user's wrist joint to be used for manipulating the device. Further features are a common channel for guiding the floss and a common fastening point, allowing both ends of the floss to be guided and attached simultaneously.

Abstract: The present invention relates to the therapeutic use of the encoding sequence of the carboxy-terminal domain of the heavy chain of the tetanus toxin and of the polypeptide encoded by said sequence, preferably for the treatment of amyotrophic lateral sclerosis (ALS).

Abstract: The present invention relates to the therapeutic use of the carboxy-terminal domain of the heavy chain of the tetanus toxin for the treatment of amyotrophic lateral sclerosis (ALS).

Abstract: The invention relates to methods based on the quantification of a set of biomarkers, preferably in biological samples isolated from skeletal muscle, for performing the diagnosis, prognosis and/or monitoring of muscular degeneration, preferably muscular degeneration caused by motor neuron diseases, more preferably amyotrophic lateral sclerosis (ALS); and to a kit for the diagnosis, prognosis and monitoring of said type of diseases. The method in the invention for the prognosis and/or monitoring of muscular degeneration makes it possible to determine the rate of progression of said degeneration (fast or slow rate of progression in relation to the normal rate of progression).

Abstract: The present invention relates to the therapeutic use of the encoding sequence of the carboxy-terminal domain of the heavy chain of the tetanus toxin and of the polypeptide encoded by said sequence, preferably for the treatment of amyotrophic lateral sclerosis (ALS).

Abstract: A system may include a static dissipative device to secure a semiconductor component, and a printer to print indicia on the semiconductor component while the semiconductor component is secured with the static dissipative device.

Abstract: A method of forming an interconnection structure in a microelectronic package, and an interconnection structure of a microelectronic package formed according to the method. The method includes: providing a combination including a first conductive layer and a dielectric layer fixed to the conductive layer; providing a hole through the dielectric layer extending from a surface of the dielectric layer to the first conductive layer; providing a recess in the first conductive layer and in communication with the hole to provide an interlocking volume under the dielectric layer; providing a conductive material in the hole and in the recess to form a package via having an interlocking section in the interlocking volume of the recess; and providing a conductive material on the dielectric layer to form a second conductive layer adapted to be in electrical contact with the first conductive layer through the package via.

Abstract: A system may include a static dissipative device to secure a semiconductor component, and a printer to print indicia on the semiconductor component while the semiconductor component is secured with the static dissipative device.

Abstract: Based on a CPU main plate (1), where the base program controlling the entire operating system, statistical data base, accounting and processing, as well as game rules, implemented, and a series of secondary plates such as the push button box (2), winnings plan (3), displays (4), upper lights (5), coin meter (6), rollers (7), coin and bill selector (8), hopper (9), electromechanical meters (10) and printer (12) with access from the exterior, which receive commands from the CPU (1) and which send information thereto, the secondary plates (2) to (10) are independent from the main plate in their order and opportunity of actuation, and independent each one of them in the configuration and level of the commands which they send to the mechanisms they control, such that the main plate (1) is unique and non-detachable, inasmuch as the secondary plates (2) to (10) can undergo modifications in both codification and number, according to the mechanisms to which they have to provide service, all the plates, main plate (1)

Abstract: As from a determined number of displays (1), (1?), (1?), three for example, through each one of which three figures (2) can be seen that are susceptible to forming various horizontal and diagonal winning lines (5), said displays additionally incorporate numerical displays (3) coinciding in position and quantitatively with said visible figures (2), but stationary, which are operative or not depending on whether or not they are lit and depending on the number they indicate at all times, these numerical displays (3) can be used for obtaining eight other winning lines (6), three horizontal ones, three vertical ones and two diagonal ones, and simultaneously used as “advance” meters that are indicative of the changes that can be made in the figures and numbers shown through the displays.

Abstract: It consists of an opaque blind (4) susceptible to covering part of the display (1) carrying the images (2) that are visible through the screen of the machine at the end of each play, for the purpose of temporarily hiding said images (2) to substitute them with others existing on the outer face of the blind (4). This blind (4) is associated to an arm (5) finished off with a ring (6) assembled with rotational freedom on a support (10), said disc ring (6) having a gearing (7) through which it receives the movement from a micromotor (9) which makes the blind (4) rock between the operating and non-operating limit positions, duly defined by a pair of end stops (11-11?) or by the electronic control of a “stepper” type drive motor (9).

Abstract: The support for a drive motor of image-bearing rollers in amusement machines constitutes an assembly allowing for its removal with regard to a general support (8) fixed to the machine, constituted of a base (1) on which the motor (2) is fixed, which has lugs (7) projecting from the base which are coupled in necks (9) arranged for that purpose on the general support, in combination with a laminar portion (12) of said base which is housed in a groove (11) arranged in the general support, said base locking to the general support by means of a tilting side arm (13) hinged to the general support, which establishes an electric contact by means of a pin connecter (4) arranged on the respective side of the base of the motor for the feed thereof, the base having in the upper part a removable handle (5) coupled by locking on said base for its gripping and removal.

Abstract: The invention is structured on the basis of two flywheels (14) and (17) which are coaxial and having different diameters, upon which respective annular bands (15) and (18) are assembled, which are concentric and consequently parallel, bearing their respective alignments of images or figures that are collated with empty and transparent areas permitting the visualization of the inner band through the outer band, said bands having independent actuation by means of respective motors (13) and (19), in turn controlled by respective optic regulators (23) and (24), such that the movement of one of the annular and image-bearing bands (25) is totally independent from the other (28).

Abstract: A thermal and acoustic barrier for automotive floor pan carpeting is made by cutting synthetic foam sheet in a continuous process to create a foam surface complementary to the three dimensional shape of the floor pan surface. The cut foam sheet is bonded to the underside of the carpeting and installed with the complementary foam surface facing the floor pan.